What is the underlying genetic defect that causes xeroderma pigmentosum?How can the symptoms of this disease be explained by the genetic defect?

Q: What are the major factors in the various mutants of the spike protein

A: Novel coronavirus (2019-nCoV, later named SARS-CoV-2 or severe acute respiratory syndrome…

Q: What do transposable genes mean? How many different transposable genes do bacteria contain?

A: Transposable genes Transposable genes also known as jumping genes are defined as the repetitive…

Q: What is DNA methylation? When we say that DNA methylation is heritable, what do we mean? How is it…

A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…

Q: What is a heterochronic mutation? How does it affect the phenotypic outcome of an organism? What…

A: Mutation means sudden changes occur in DNA sequences. The mutation occurs randomly. It also occurs…

Q: What are holandric genes?

A: Holandric genes are genes that are found on the Y chromosome that are not homologous to any other…

Q: Why is the p53 R273W mutation preventing p53 from binding to DNA?

A: All living things are made up of cells, which are the most basic and important unit. All of life's…

Q: How do translocations such as the Philadelphia chromosome contribute to cancer?

A: Translocations generate novel chromosomes, a segment from one chromosome is transferred to a…

Q: What is the genetic basis that causes the symptoms of Downsyndrome?

A: Genetic diseases can be defined as the diseases which is cause due to the change in the genetic…

Q: How many genetic variants are there?

A: The specific portion in the genome that differs between the genome of two individuals is called…

Q: What is terminal deletion in genetics?

A: A single break may cause terminal deletion; but, due to the need for specific chromosome tips…

Q: What is the effect of inversion mutation?

A: Mutation is a change in the sequence of genetic material either due to the mistake in replication or…

Q: Regarding albinism, with adavances in fields such as gene therapy and stem cell research, is there a…

A: Introduction :- Albinism is an inherited condition in which the rate of melanin production is…

Q: What is A hypermorphic mutation?

A: The mutations are classified based on their behavior in terms of genetic interactions. The Nobel…

Q: What are the possible genotypes of the PTC locus?

A: * genotype means collection of genes that  refers to two alleles of a particular gene and genotype…

Q: What is the genetic basis of the symptoms of Down syndrome?

A: Ans: In humans various diseases or disorders are caused by chromosomal aberrations or mutation in…

Q: Can someone give me a few inherited disorders that are NOT caused by mutations? and if possible,…

A: Tay Sachs disease- Children's with the tay Sachs disease appears healthy at birth but becomes…

Q: How will this mutation affect the golden retriever puppy?

A: Transcription is the process which makes mRNA from DNA in complementary manner. The A, U, G and C of…

Q: What is the chromosome abnormality in cri du chat syndrome?

A: Cri-du-chat syndrome, commonly known as 5p- (5p minus) syndrome. Infants with this syndrome…

Q: What category of genetic disorders does albinism disord

A: Answer  Albinism is a single gene defect and it is a type genetical disorder.

Q: Is Down syndrome a mutation?

A: The genetics is the branch of biology that deals with the study of genes, genetic variation and…

Q: What is recessive mutation ?

A: The change in the sequence of nucleotides in the genome of an organism is called a mutation. This…

Q: What occurs during duplication chromosomal mutation?

A: Mutations are defined as sudden heritable change which alters the expression of a gene.

Q: Based on the pedigrees of the Finnish families, what type of inheritance does lactose-intolerance…

A: Answer: Introduction: Autosomal recessive inheritance is a type inheritance in which genetic…

Q: Why would a mutation in a somatic cell of a multicellular organism not necessarily result in a…

A: Eukaryotic organisms have two types of cells: germ cells which produces gametes and somatic cells…

Q: Why is knowing the genetic basis of a trait such as blond hair important? Why would scientists go to…

A: Genetics is the study of genes, their interactions, and the effect of environment on genes. Broadly…

Q: . What is DNA methylation? When we say that DNA methylation is heritable, what do we mean? How is it…

A: Gene regulation is the process through which the cells control the expression of genes. This is…

Q: What are genomic variants?

A: The term variant is often used to refer to a specific region of the genome which differs between two…

Q: determining coat color is the agouti gene?

A: The coloration, pattern, and length of the cat fur is governed by numerous genes and is determined…

Q: Why is the incidence of survivable genetic disorders involving deletions of parts of chromosomes so…

A: Deletion is a type of mutation in which a part of DNA molecule is not copied during DNA replication.…

Q: What causes short stature in Turner syndrome?

A: Answer: Introduction: Turner syndrome (TS) is commonly found chromosomal disorders. It appears…

Q: What is a microdeletion?

A: Chromosomes are structures present in the nucleus of the cell. The chromosomes are formed of DNA…

Q: What is the significance of the Philadelphia chromosome, and how is it related to leukemia?

A: Chromosomes are the structures present in the nucleus that appear thread like and contain genes.…

Q: What are anonymous DNA polymorphisms?

A: Deoxyribonucleic acid (DNA) polymorphism is the difference of DNA among the members of the same…

Q: What genotype would a long haired guinea pig have?

A: A genotype is set of heritable genes which can be passed from parents to offsprings.Genotype is the…

Q: what is another type of disease caused by a duplication mutation? How does it present itself?

A: Mutation can be defined as any random change that occurs in the DNA sequence. A rapid change in the…

Q: How do the egl-1 and pos-1 phenotypes interact? Do you think this is a meaningful genetic…

A: Caenorhabditis elegans, a nematode is a useful genetic model to study RNA interference technique…

Q: Why are mutations in the INK4 locus so dangerous?

A: INK4 is a cyclin-dependent kinase inhibitor family (CKIs). Inhibitors of CDK4 and CDK6 are…

Q: What is intergenic mutation ?

A: Mutation is a phenomenon in which some changes or alterations occurs in the original gene sequence.…

Q: What is the difference between DNA and protein methylation?

A: Methylation is a type of epigenetic modification which regulates gene expression.

Q: What are the  chromosome 5 mutations?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: What is retrograde?

A: Introduction  The proteins which are formed by the ribosomes attached over the ER are transported to…

Q: What are the similarities a chromosomal mutation and point mutation?

A: Chromosomal mutation is a numerical or structural change in a chromosome. It causes Klinefelter…

Q: Can a harmful mutation-causing genetic disease exist from generation to generation without…

A: Genes are DNA pieces or fragments borne on the chromosomes that decide particular human traits, such…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.