Which of the following factors accelerate cellular aging? O A. Developmental senescence in embryogenesis O B. Accumulation of misfolded proteins O C. Regenerative senescence in wound healing O D. Entry into G1 phase of Cell Cycle
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- QUESTION NO. 1 Cystic fibrosis is a frequent generic disease of Caucasians. The CF gene codes for a protein called the cystic fibrosis transmembrane conductance regulator (CFTR) which functions as a cAMP-regulated chloride channel. The protein has two membrane-spanning domains, two domains that interact with ATP, and one regulatory domain. The most common defect is in the gene for one of the ATP binding domains. The result is a protein that does not fold correctly in the endoplasmic reticulum, is not properly glycosylated, and is nor transported to the cell surface. Rather, it is degraded in the cytosol within proteasomes. Drugs that foster chaperone interaction with the mutant protein are a potential therapeutic approach. Chaperones A. are always required to direct the folding of proteins. B. when bound to protein increase the rate of protein degradation. C. usually bind to strongly hydrophilic regions of unfolded proteins. D. sometimes maintain proteins in an…QUESTION 16 Match the definitions and key words with the group name (programmed or stochastic). From the drop down boxes, choose the correct letter (A -- Programmed or B -- Stochastic). Celluar Aging: suggesting that the lifespan of a species is determined by an internal cellular "clock" that limits the number of cell divisions. Immune System: suggesting that aging is due to a break-down in the body's natural defense system against bacteria, viruses, and other substances. Error Theory: suggesting that errors at the cellular level produce "faulty" molecules. Evolutionary theory: suggesting that aging is a natural way to limit the reproductive potential and timespan of members of a species. Wear and Tear: suggesting that like a battery or a machine, the human…Question 3. Eukaryote cells are living cells that are specialized to deal with changes in the external environment. A. Describe how the processes of Phagocytosis exhibited by the Amoeba represent a cell responding to a change in the environment. B. How is the process you described in "A" similar to the way the White Blood Cell (WBC) might react to a bacterium or a virus that invades the tissues of a human being.
- Question 24 pts When we are vaccinated against SARS-CoV-2, what happens? (select all correct answers) Group of answer choices a) Our adaptive immune system becomes primed to recognize the SARS-CoV-2 virus. b) Our DNA becomes modified. c) We will permanently have viral proteins in our cells d) Our cells will make a partial or complete viral protein, which our immune system will recognize as foreign. e) Memory cells will be ready for a new infection.Question 14 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above. Use the left-hand menu to view the sequence for CACNA1S, and answer the following question. ANSWER ONLY IN UPPERCASE LETTERS, NO UNITS. What are the last six nucleic acid bases of exon 1? Answer: The last six nucleic acid bases of CACNA1S, exon 1 are Blank ...Question 16: One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above and use the information and link-outs from the page to answer the following question. GIVE YOUR ANSWER AS A NUMBER ONLY, NO UNITS: What is the size in amino acid residues of the CACNA1S transcript named CACNA1S-202?
- QUESTION 35 True or false? If a treatment were developed that could extend the lives of lung cancer patients by several years, the incidence of the disease would increase.Question 13 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above and use the information and link-outs from the page to answer the following question. GIVE YOUR ANSWER AS A NUMBER ONLY, NO UNITS: What is the size in amino acid residues of the CACNA1S transcript named CACNA1S-202? Answer: The size of the CACNA1S transcript named CACNA1S-202 is Blank ... amino acid residues.Question 12 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above and ensure that you click to reveal the transcript table. Then use the information in the table to answer the following question. PLEASE GIVE YOUR ANSWER AS A NUMBER ONLY, NO UNITS What is the size in base pairs of the CACNA1S transcript named CACNA1S-202? Answer: The size of the CACNA1S transcript named CACNA1S-202 is Blank ... base pairs.
- QUESTION 34 During fruit fly development, a transmembrane protein called Delta on the surfaces of presumptive neurons binds to a receptor, called Notch, on the surfaces of the immediately adjacent cells. This signals to the adjacent cells not to differentiate into neurons. This mode of signaling is: juxtacrine paracrine autocrine endocrineQUESTION 26 One of the cultural preferences driving couples to continue having children in India is ____. a. the preference for female children b. a child benefit paid by the government c. the desire to have both male and female children d. a prohibition against birth control methods e. the preference for male childrenQuestion 5 Mutations are random events. True or False