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- Which of the following groups of antimicrobial drugs selectively targets bacterial cell wall synthesis? beta-lactams quinolones sulfonamides polymyxins phenolsChanges in the bacterial genome can lead to resistance to antimicrobialdrugs. what the different ways that these changes in the DNA occur?What bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.
- Name three types of antimicrobial proteins.Technically speaking, which antimicrobial drugs are produced naturally? Biofilms Antibiotics Semisynthetics SyntheticsCould an organism that is susceptible to an antimicrobial agent in laboratory testing fail to respond to it when that drug is used to treat the patient? Explain.
- Why are antimicrobials inhibited in the presence of organic matter?Give a short comparison between alcohols and aldehydes as chemical antimicrobial agents.Which of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic index
- How can some bacteria become resistant to antimicrobial drugs?Identify two factors( in detail)that make biofilms more tolerant to antimicrobials including their mode of action.Broad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.