Which of the following statements is true about the control of muscle glycogen phosphorylase? a) It is activated by phosphorylation by an active phosphorylase kinase b) It is allosterically activated by ATP c) It is allosterically activated by CAMP d) Normally it exists in active form
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Q: the
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- What is the function of myosin light-chain kinase in smooth muscle?From the following choices, choose the THREE, that would result in prevention of muscle contraction (in other words, which three descriptive changes below would result in flaccid paralysis of a muscle). exocytosis of acetylcholine is constant, even without action potential injection of botulinum toxin calcium cannot be pumped back into the terminal cisternae acetylcholine receptor remains open to sodium active sites on actin a permanently exposed dramatically increase the activity of acetylcholinesterase calcium cannot bind troponinName the system that provides a ready supply of phosphocreatine to muscle cells and describe where the different components of this system take place.
- The single-fiber twitch experiments shown here were generated by stimulating the muscle cell membranes to threshold with an electrode and measuring the resulting action potential and force. How would the results differ if Ca21 were removed from the extracellular solution just before the electrical stimulus was applied?What are the Regulatory Molecules that mediate exercise-induced changes in muscle?In the process of muscle contraction, which of the following steps immediately precedes the sliding of tropomyosin causing exposure of actin? binding of acetylcholine to its receptor binding of calcium to troponin exocytosis of acetylcholine at NMJ binding of myosin head to actin's active site binding of ATP to the myosin head
- In light of the “all or none” law of muscle contraction, how can you explain twitch recruitment (also called the graded response) when stimulating the muscle versus stimulating the nerve? Explain the difference in stimulation voltage required to elicit a maximum response when stimulating the nerve versus the muscle directly?Describe the sequence of events by which an action potential in a motor neuron produces an action potential in the plasma membrane of a skeletal muscle fiber?Which of the following causes ( the state of ) rigor in skeletal muscle ?a) lack of atp b) decrease of intracellular ca2plus c) increase in intracellular ca2+ d) lack of action potential in motor neurons
- With regard to muscle contraction, which of the following is an INCORRECT statement with regard to the interactions of filaments that occur in the sarcomere? A. When muscles are relaxed tropomyosin blocks binding sites on actin subunits, which keeps cross-bridges from forming. B. The myosin heads conduct a power stroke motion to slide when bound to actin, to move the "thin" filaments towards the center of the sarcomere. C. During contraction, actin subunits are removed from the ends of the "thin" filaments to shorten actin polymers, thus reducing the length of the sarcomere. D. "Thick" filaments are anchored at the M-line, while "thin" filaments are anchored at the Z-line. E. Numerous myosin heads engage with the actin filaments simultaneously, such that there is no back-slipping during the contraction process.In the process of muscle contraction, which of the following steps immediately precedes the influx of sodium into a myofiber at the neuromuscular junction? release of calcium from the terminal cisternae sliding of tropomyosin causing exposure of actin propagation of an action potential down the t-tubules binding of myosin head to actin's active site binding of acetylcholine to its receptorOutline the molecular mechanism for skeletal muscle contraction. At what point is ATP used and why?