While Rituximab has increased survival in CLL patients, it has adverse effects including (1) reduced immunoglobulin levels and (2) increased risk of certain infections. Discuss the underlying mechanisms of these adverse effects in patients receiving rituximab-based therapies.
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- True or False. To increase adherence, vancomycin should be administered via the PO route to treat cellulitis of the left leg.Briefly present the most common drug interactions with warfarinThe Klein and Mancinelli (2021) textbook describes a Level IX and a Level X on the RLA. How would a clinician working in an outpatient facility find those extra levels useful when treating their clients with TBI?
- Antihypertensive treatment with calcium channel blockers (CCBs) is often offered to patients with stage 2 hypertension. Please describe the intracellular signaling events, mechanisms of action on blood vessels and important adverse effects of CCBs. In addition, describe considerations such as the age of a patient when prescribing a CCB at the first stage of antihypertensive therapy according to NICE guidelines.Explain the principles of the different methods used for the diagnosis of HDFN. Define Rh-immune globulin and describe its function. Identify the indications and contraindications for administration of Rh-immune globulin. List the tests used for detecting fetomaternal hemorrhage. Outline the protocol for testing maternal and cord blood in cases of suspected HDFN.Discuss the clinical indication and side effects of Rifamycin.
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