Electric potential

globus pallidus play an important regulatory role of GABAergic activity. Therefore, stimulation of dopaminergic receptors is also involved in the modulation of pallidal firing. The depletion of dopaminergic stimulation in the pallidus suggests a potential role in PD motor deficits and correlation with symptoms such as tremors and dyskenisia (1,2) .Interestingly, experiments conducted in non-human primates have demonstrated that a decrease in dopaminergic inputs to the globus pallidus, due to degeneration

By comparing our nervous system to that of a computer, there is lots to understand. Our bodies and the mechanic makeup of a computer are composed of a wiring or nervous system that transmit information through signals. Our nervous system can be broken into two parts; the peripheral nervous system (PNS) and the central nervous system(CNS). The peripheral nervous system is responsible for all other parts of the body outside the brain and spinal cord. The nerves in the in the PNS are connected to our

Structure: The spinal cord is a white, soft and cable-like material running through the backbone. The inner fabric of the spinal cord is much simpler and more uniform from its many parts the brain. Inside The spinal cord filled with neurons without having myelin sheath in their axons, Because it looks gray. The spinal cord connected to the thirty-one pairs of peripheral. Spinal nerves, The wire at the back or dorsal part is attached to the sensory spinal nerves. There are two (left and right) dorsal

Nitric Oxide is essential for penile erection. Erectile Dysfunction (ED) is associated with reduced NO synthesis or reduced release in the erectile tissue. The isoforms of NOS, eNOS and nNOS mediate penile erection. These isoforms are regulated by NOS cofactors, calcium, calcium binding protein calmodulin, oxygen and reduced NADPH. After the increase in intercellular calcium production, NO is generated in low amounts. Upon neural depolarization in nNOS containing nerve terminal in penis, neural NO

People have been smoking marijuana for years. In the early 1900s marijuana was legal in The United States. American government did their research and found out marijuana is bad for their people’s physical status and many other parts of the body. Marijuana is bad for your health because it affects your mental and physical conditions. Marijuana can hurt your well-being in a lot of different way, one of the ways that it affects marijuana smokers is through their brain. Marijuana changes the way you

Back Pain and Tendons The skeletal muscles supplies us movement, which is supported by the posture. Our muscles will shorten, tighten, contract, and promote mobility. The muscles join with bones that attach to the tendons. Once the muscles begin contracting, the muscles are stimulated and join the fibers through our motor neuron cells. The nerves makeup axon, body of cells, dendrites, etc, and these elements transmit impulses to the nerves, sending the impulses to the major components of our system

through the skin and skull noninvasively to targeted deep brain regions, it may offer alternative approaches to existing methods of neuromodulation. While the exact mechanisms of neuromodulation via FUS are not fully understood, a general overview of potential mechanisms underlying the actions of ultrasound on neuronal excitability can be provided. Localized

The purpose of the experiment was to observe the effect of the antimitotic drug cytochalasin D on the organization of actin in human fibroblasts. The human fibroblasts were treated with increasing concentrations of the antimitotic drug and viewed using fluorescence microscopy. With each increase in concentration of cytochalasin D, we successfully observed that the presence of stress fibers decreased. The treatment of 10µM of cytochalasin D indicated that higher concentrations consistently alter actin

An arriving action potential depolarizes the axon terminal of a presynaptic neuron. Calcium ions enter the cytosol of the axon terminal, which results in acetylcholine release from the synaptic vesicles by exocytosis. Ach diffuses across the synaptic cleft and binds to receptors on the postsynaptic membrane. Sodium channels open, which produce a graded depolarization. Ach is broken down into acetate and choline by AChE, which causes depolarization to end. The axon terminal reabsorbs choline form

Pathophysiology of epilepsy- Epileptic seizures arise from an excessively synchronous and sustained discharge of group of neurons [9].Abnormal cellular discharges may be associated with various causative factors such as trauma, oxygen deprivation, tumors, infections. Although different types of epileptic syndromes differ pathophysiologically, ictogenesis related mechanisms are often common. It is generally accepted that ictogenesis results from hyperexcitability of neuronal membrane. Both neurotransmitters