This was a cohort study with a survival analysis of an adult population of PLWH attending specialized care services for HIV/AIDS in the state of Pernambuco, in the northeast of Brazil. The study was located in two hospitals from the Brazilian integrated health system (Sistema Único de Saúde -SUS), Hospital Universitário Oswaldo Cruz (HUOC) and Hospital Correia Picanço (HCP), which encompassed 70% of PLWH in our state at the time of recruitment. The study was approved by the Ethics Committee of the Universidade Federal de Pernambuco (CEP/CCS/UFPE 254/05), and all participants underwent the informed consent process prior to being enrolled in the study. This report follows the STROBE (STrengthening the Reporting of OBservational studies in Epidemiology) checklist. The study population consisted of outpatients and inpatients at the HUOC and HCP, of whom less than 5% refused to participate, resulting in a consecutive sample of 2372 PLWH enrolled from July 2007 to June 2010 and followed until December 2012. The participants were aged 17 years or over; and no criteria were established for exclusion or withdrawal from the study. The outcome was the event of death, classified as immunodeficiency-related or immunodeficiency-unrelated. The monitoring and collection of data regarding mortality were conducted periodically with searches on the Pernambuco Mortality Information System (SIM) database, which thus prevented loss to follow up until the study terminated on 31st December 2012.
This large population has dealt with and suffered from several detrimental diseases. Even before the 2010 earthquake, nearly half the causes of deaths have been attributed to HIV/AIDS,
(2011) was a multi-continent, randomized, controlled trial to evaluate the effectiveness of antiretroviral therapy on the speed of the disease process among HIV-1 infected and HIV-1 uninfected partners. In the study, 1,763 HIV mixed status couples were grouped into either early antiretroviral and delayed therapy groups. Inclusion criteria consisted of the HIV-1 infected participant having a CD4 count between 350 and 550 with no previous antiretroviral therapy usage, except to prevent mother-baby transmission. Participants attended three monthly sessions and then quarterly sessions until ill or requiring an additional amount of antiretroviral drugs (Cohen et al, 2011). The uninfected partners were tested each quarter for seroconversion, the period in time in which antibodies become detectable. The research study concluded that early antiretroviral therapy initiation had a greater effect on CD4 count than delayed antiretroviral therapy. The average CD4 count in the early therapy group originated at 400 and increased to 603 after 12 months of ART. A decline of CD4 cells were noted in the delayed group (Cohen et al, 2011). The authors concluded that a higher incidence of HIV transmission was noted in African countries and adverse effects were more likely to occur in the early therapy group. Early therapy had a positive effect on the HIV-1 uninfected and HIV-1 infected
Human immunodeficiency virus (HIV)/AIDS is a pandemic problem affecting global health. At the end of 2015, 36.7 million people were living with HIV/AIDS globally. The rate of incidence is more prevalent in Sub-Saharan Africa with almost 1 in every 24 adults living with HIV/AIDS. In the united states, HIV/AIDS is a diversified health problem affecting all sexes, ages and races and involving the transmission of multiple risk behavior. However, with the introduction of various prevention programs and antiretroviral drugs, the incidence of HIV/AIDS has reduced.
Human Immunodeficiency Virus (HIV) is a serious condition in our society. If left untreated, HIV can progress to Acquired Immunodeficiency Syndrome (AIDS) (CDC, 2016a). Once a person is infected with HIV, it can never be completely removed from the body, meaning they are infected for the remainder of their life (CDC, 2016a). HIV was initially thought to be a problem only in younger generations (Ellman, Sexton, Warshafsky, Sobieszczyk, & Morrison, 2014). However, evidence has emerged suggesting that an epidemic may be brewing in the older adult population (Ellman et al., 2014; Karpiak & Brennan-Ing, 2016; Robnett & Chop, 2015). I decided to research this topic, because I personally had no idea that HIV was so prevalent in this age group.
Observational epidemiology is a study of disease where “the investigator ascertains exposure and outcome without assignment to an intervention” Observational studies have made important contributions to the knowledge and understanding of health-related conditions. These studies usually involve a large group of individuals as in a community. The purpose of this type of study is to determine the
Although these measures may not be as important as medical visits frequency and viral load suppression, these factors are a contributing aspect to the health and improvement of people living with HIV. Poor oral health can lead to malnutrition. If the person is unable to chew or swallow because of pain from their mouth or a laceration, the person may not receive enough food to stay healthy. Consequently, this may result in how their body responds to HIV medication or pathogens. In turn, any infection can stimulate the virus to grow, causing a loss of viral loads. Furthermore, hepatitis C is the most common infection associated with HIV, but is neglected by more than half of the grantees. If grantees could just conduct the screening and letting the patient decide if he or she wants treatment, it would be beneficial rather than not screening any at
Human Immunodeficiency Virus is HIV that develops into AIDS, which is Acquired immunodeficiency syndrome. This virus starts to break down white blood cells, as a result the immune system starts to deteriorate and our greatest shield cannot fight any longer (Mayo Clinic, 2016). The CDC (2015) states, that over 1.2 million people live with HIV in the United States and most who are infected are oblivious of their disease. Healthy people 2020 has declared HIV a public health crisis in the United States, and continues to sweep the nation with more than 500,000 new cases each year (HealthyPeople2020,2016).
In 2014, 1.2 million people died from HIV and its related causes. In the same year, about 36.9 million people were living with HIV. Among these, 2 million were newly infected in 2014. The rate of infection has reduced by 35% between the years of 2000 and 2015. Between the same years, mortality due to HIV fell by 24%. The area with the most HIV/AIDS victims is Sub-Saharan Africa. In this region, 25.8 million people were living with HIV in 2014. The region also has 70% of the newly infected victims in the world. It is very unfortunate that more than 50% of people with HIV know that they have it. HIV testing efforts have improved with 150 million in 129 low and middle income counties getting tested. It was reported in 2015 that 15.8 million people were receiving antiretroviral therapy (World Health Organization,
Diseases have been affecting the globe for decades. In recent years there have been many infectious diseases have been occurring and spreading across society. Out of the many infectious diseases, there are two that are going to be examined. The two diseases that are going to be analyzed and reviewed are Ebola and AIDS. The two diseases have a high rate of death among people who have been infected. The right rate of death has occurred for decades. Both of these diseases are highly effective at attacking the immune system of the victims. These diseases are both infectious, but are different in several ways. In order to understand how to treat or contain these two diseases, it is informative to be educated on each disease, how it is spread, and what symptoms are prevalent.
“Human immunodeficiency virus (HIV) is a blood-borne virus typically transmitted via sexual intercourse, shared intravenous drug paraphernalia, and mother-to-child transmission (MTCT), which can occur during the birth processor during breastfeeding.” There is no cure for HIV or AIDS but over time different types of medications have been developed that slows down the advancement of the disease. AIDS is a lethal disease that is caused by HIV. HIV destroys the immune system and causes the body to not be able to fight off any diseases.
Research is relevant to nursing with a specific end goal to interpret obstructions, increment estimation of patient care, propose new thoughts for future research, and shape the benchmarks at which we rehearse at. Studying research permits experts the capacity to decide qualities and shortcomings in every specific piece. Evaluating is imperative to bolster or expose conclusions found by the examination directed. Supporting or exposing research takes into consideration medical attendants to reinforce proper patient mediations and execute them with the most extreme endorsement. It is imperative for me to understand how to properly critique research for my career as a nurse so that I can stand by the medical
In the 1980s, a mysterious disease began to take the lives of Americans. With the cause unknown, a fear grew among Americans. An unusually high rate of people was becoming sick with strange and rare diseases. When experimental treatments failed to work, people died. This mysterious disease is what we now know as HIV–Human Immunodeficiency Virus. In the past thirty-five years, the HIV has taken many turns in history. Although we do not hear about HIV and AIDS now, it is still a prevalent issue in the United States and in the world.
“Epidemiology is the study of the distribution and determinants of health-related states or events (including disease), and the application of this study to the control of diseases and other health problems (WHO, 2015)”. “Various methods can be used to carry out epidemiological investigations: surveillance and descriptive studies can be used to study distribution; analytical studies are used to study determinants (WHO, 2015)”.This paper discusses about epidemiology of HIV infection, including factors that contribute the development of the disease, epidemiologic triangle, role of community health nurse and the national organization that address the communicable disease.
HIV, or the Human Immunodeficiency Virus, is a virus which damages and kills cells of the immune system. It attacks the T-cells, key cells of the immune system, and uses them to make copies of itself. After being infected with the virus it progressively interferes and eventually destroys the immune system's ability to fight the anti-genes. HIV may develop into the syndrome AIDS, the Acquired Immunodeficiency Syndrome. HIV is an STD - a sexually transmitted disease - and therefore most commonly it is spread through sexual contact, and the virus mainly enters the body through the penis, mouth, lining of the vagina or vulva during sexual activity. HIV can also be spread through sharing syringes or needles with someone who is infected with the
HIV is the human immunodeficiency virus that causes AIDS. A member of a group of viruses called retroviruses, HIV infects human cells and uses the energy and nutrients provided by those cells to grow and reproduce. AIDS (acquired immunodeficiency syndrome) is a disease in which the body's immune system breaks down and is unable to fight off certain infections, known as "opportunistic infections," and other illnesses that take advantage of a weakened immune system. When a person is infected with HIV, the virus enters the body and lives and multiplies primarily in the white blood cells. These are the immune cells that normally protect us from disease.