Essay about Addiction and the Brain

Addiction, it is all around us, affecting people from all walks of life, it is not limited to certain social classes or lifestyles. It is found in every ethnic group, regardless of gender or age. It affects our neighbors, our friends, and our family either directly or indirectly. Although substances such as alcohol and illegal drugs are two of the most common addictions we hear about, there is a wide range of substances and even activities such as gambling and shopping. There is some debate whether addiction is a brain disease or a choice.

Brain chemistry is a detailed system that helps the brain to interact with the chemicals that moves important around the brain. Brain chemistry changes depending on what substance or how much of the substance is used. These changes can indicate signs of the beginning of an addiction over time if the drug use begins to get worst it can lead to dramatic changes in the brains over all chemistry. This example supports the theory of brain change ”‘when we elevated levels of ΔFosB in the NAc, the mice exhibited behaviors that are considered reliable indicators that exposing people to the same conditions would cause addiction: They showed more sensitivity to the drug (responded to doses one-third those required to produce a response in normal animals), self-administered more drug, and displayed greater drive (or craving) for cocaine (they worked two to three times as hard to get the drug) ().” The opposing side stated this as their disagreement “human psychology is simply the reflection of human neurophysiology. Thus, for instance, although the authors claim that their account of addiction is relatively 'skeptical,' and has less explanatory power than that of their opponents, they nevertheless seem to accept at least the possibility of a complete account, which will only come about as a result of 'further advances in biological and psychological science (Foxcroft, L. J.

Dopamine is defined as a neurochemical that supports fine motor activity, blood pressure, focus inspiration, intuition, and joy, among other functions (“Dopamine”). The brain interprets all items of pleasure in the same manner. Whether someone has sexual intercourse, eats a delicious meal, or smokes marijuana, the brain releases dopamine in the same fashion. Drugs ranging from nicotine to heroin all produce the same signals in the nucleus accumbens, which is a group of nerve cells that sits below the cerebral cortex (“Understanding Addiction: How Addiction Hijacks the Brain”). In “Violence in Movies, Music, and Media,” by Jeanne Nagle, dopamine is compared to a shot of a heavy-duty amphetamine (38). The entertainment an individual finds in shooting another person on a TV screen is the same as one who watches a violent movie that interests them as well. As dopamine is released, the brain naturally wants more as it is very addictive by nature (“Understanding Addiction: How Addiction Hijacks the Brain”). Rosner for example, the man addicted to videogames, could sit down and be vegetative for 18 hours at a time playing his favorite game. The dopamine released while playing was enough to almost shut down his prefrontal regions in his brain that affect judgement and concern – leading him to play more and more violent games (Linden). People who begin as mildly curious or interested in the world of violence, zombies, and vampires can quickly become an addicted expert on the subject

Many people believe the misconception that an addiction is a moral problem and not a disease. To better understand the reasons why an additicition is in fact a disease; I will identify several types of addictions, and the problems associated with them. I will examine reasons why certain people are more susceptible for developing an addiction. Also, I will determine why many addicts deny their problems and many recovery methods addicts use to fight their illness. Researching these issues, will help aid my claim that addiction is a disease.

It is believed that certain individuals are predisposed or vulnerable to addiction based on biological, psychological and social influences. The euphoric high produced by many addictive substances is the result of overstimulation of the “pleasure center” of the brain. This is the same area that controls emotions, fear, self-control and overall feelings of wellness. The presence of these foreign chemicals creates a response that the brain will crave as soon as it fades. The brain’s chemistry works against its own health, as it rewires its decision making faculties around the primary goal of finding and taking more of the drug” (1). Many people mistakenly believe that psychological addiction is somehow less serious or real than physical addiction. The psychological aspects of addiction are much more challenging to repair and recover from than the physical addiction. Psychological addiction can last for years or even a lifetime.

Addiction: is it a disease or a choice? A disease can be described as “a disorder of structure or function that produces specific signs or symptoms, or that affects a specific location and is not simply a direct result of a physical injury.” Knowing this, one can believe addiction is a disease. It is something that is done frequently, that usually does not end, just as a disease; it cannot cease on its own, because it requires some form of treatment. The big question regarding addiction is why people believe it to be a choice opposed to a disease.

The user may increase the amount of a drug taken due to the drug being metabolized too quickly or being removed from the body. A person may compensate their behavior when exposed to a drug overtime such as learning to drive while intoxicated. The impairment is reduced and this is known as behavioral tolerance. Pharmacodynamics tolerance is the main contributor to the need to increase the dosage of a drug in order to avoid withdrawal symptoms. The user does not feel the same effects of a dosage so the dosage must be increased in order to get the same feeling.

Wise and Koob state that addiction begins with positive reinforcement, habits, a person feels the “high” of the habit, however, then the tolerance sets in which conditions the brain for negative reinforcements and one increases the use to enjoy the habit (2014). According to the National Institute on Drug Abuse (2012), drug addiction is a chronic brain disease. This disease is complex disease that is treatable, however it is a lifetime of treatment, sending many into relapses over and over again. The Diagnostic and Statistical Manual of Mental Disorders (DSM-5)

Other drugs, such as amphetamine or cocaine, can cause the nerve cells to release abnormally large amounts of natural neurotransmitters or prevent the normal recycling of these brain chemicals. This disruption produces

Basic neurobiological research has improved our understanding of the biological and genetic causes of addiction. These findings have helped establish addiction as a biological brain disease that is chronic and relapsing in nature (Leshner, 1997). As the central nervous system is considered to be the communication pathway to the entire body with the brain being its control mechanism. The brain processes sensory information from throughout the body, guides muscle movement and locomotion, regulates a multitude of bodily functions, forms thoughts and feelings, modulates perception and moods, and essentially controls all behavior (Leshner, 1997). The body and brain then become defendant on this stimuli, as the body and brain adjust to the rewards of receiving this type of sensation. This is where the substance abuse and addiction problems

“Can Neuroscience Improve Addiction Treatment and Policies?” is a research that focus in the causes and effects of drugs in the brain. There is not explanation or analyses in the probable social and cultural causes and effects for using a drug.

And, in one way or another, almost all drugs over stimulate the pleasure center of

Addiction is like all behaviours “the business of the brain”. Addictions are compulsive physical and psychological needs from habit-forming sustenances like nicotine, alcohol, and drugs. Being occupied with or involved in such activities, leads a person who uses them again and again to become tolerant and dependent eventually experiencing withdrawal. (Molintas, 2006).

Among the numerous definitions for addiction, there lies yet another to define it from a biochemical perspective. Milkman (1983) defines it as “self-induced changes in neurotransmission that result in social problem behaviors." This definition encompasses the psychological, biochemical and social aspects of addictive processes. It is not limited to substance abuse and can be applied to any activity characterized by compulsion, loss of control and continuation of the substance despite harm. This has helped investigators gain a better understanding of the nature of addiction.

When a mother brings her young son along with her to a methadone clinic for her daily dose, each nurse and staff members looks upon the little boy with worry. Is this child in risk of falling into the same patterns simply because his mother will find it difficult to teach him differently? Or, is he predisposed to drug dependence due to his own DNA? While drug dependency has not yet been reduced to a few "undesirable" genes in the human genome, most, if not all, scientists will agree that the risk of drug dependence is largely heritable. Why does drug dependency depend on genetics, and are there environmental factors as well?