CRISPR Cas-9: The Dangers Of Genetic Engineering

We are living is a world where very soon it will be possible for people to create ‘designer babies’ that have all the features they wish for. In the article Building Baby from the Genes Up, Ronald M. Green talks about all the positive impacts that genetic modification of human beings can have on our future generations. Green acknowledges some of the negatives such as parents creating perfect children and being able to give them any trait the parent wants. However in the end he comes to the conclusion that the positive impacts of getting rid of genes that cause obesity, cancer, learning disorders, and many other diseases and disorders, outweighs the negative aspects. Richard Hayes, author of Genetically Modified Humans? No Thanks, takes the stance that we should not be able to change anything about human beings through genetic modification. He believes that once we start modifying a few features, it will slowly turn into every parent altering as many of their babies’ genes that they want. While he does acknowledge the positive impacts of getting rid of negative genes such as Tay-Sachs, he believes that it is not worth the risk of having parents manipulate all their future children’s genes to their liking. Green and Hayes stand on opposite sides of the debate about genetic modification of human beings and this essay will explore the similarities and the differences of their articles.

magine, 20 years from now, sitting in a cold doctor's office deciding the genes of your unborn baby, what color hair, eyes, speed of metabolism, height would you even know what to pick? Impossible you might say but in this day and age technology is growing ever so rapidly that picking the genetic makeup of your baby is closer than you might think. The technology is called CRISPR. This technology doesn't only have the ability to change physical traits, but genetic traits specifically genetic abnormalities and diseases. 20 years ago, no one would have ever thought we would have the answer to, in theory, cure every genetic disease from sickle cell anemia to cystic fibrosis. However, with great scientific breakthroughs comes questioning and

Humans have been genetically engineering organisms for nearly 10,000 years using traditional methods of modification—among these methods include selective breeding and crossbreeding. Though effective, these methods were unreliable and were only able to change certain traits. A lack of control over our genetic material proved to be a clear hindrance to our species; when harnessed, advancements in other fields of knowledge would be immeasurable. Once seen as an impossible task, scientists have been able to exploit genes and take control of them. CRISPR-Cas9 is a system that allows scientists to cleave off sections of DNA and artificially modify them by inserting a mutation into the place of the old DNA. This is exceptionally precise, whilst

What if there was a future where having a child was as simple as selecting desirable genes out of a catalogue? A future where technology granted parents the ability to design and perfect their children. The notion of “Designer Babies” seems absurd; however the rapid development of technology and the potential of gene manipulation could make this a startling reality.

Charles Darwin started it all. His theory of evolution and natural selection in 1859 lead people to question the biological limits of human society (Rose). Then came Hitler’s ideas in the 1930’s. His desire to create a dominant human race sparked the eugenics movement, the idea that the humans could be genetically improved by selective breeding (Rose). Even if this can be done, is it right to genetically modify fetuses? Furthermore, is there a line between changing a baby's genome in order to avoid disease and designing a baby with desirable traits?

If it is possible to cure genetic disorders in unborn children, then why does this dilemma exist? Designer babies may offer a solution for many parents faced with an uncertain future. The term “Designer Babies” refer to children who develop from embryos that are selected, or genetically modified in vitro (outside of the human body, usually in a laboratory). While emerging technology is constantly improving the daily lives of mankind, the scientists involved in this branch of science have fallen under great scrutiny despite their best effort to contribute to society. As a developing science, the exploration of genetic editing has potential to direct humanity to a radiant future. Financially funding and

Day by day, an accretion of advancements and improvements are formed across the world. Prominent developments occur rapidly, like the use and creation of technology. Technology has and continues to create an immense effect on how we live our daily lives. Its use is ranged from how information is found, travel, communication, and more. However, the advancements of technology seems to interfere with the circle of natural life, life that is brought into our world. It has changed the lives of unborn children, whom are in the form of an embryo. Altered by a new technique and process of genetic modification, that is commonly referred to as “Designer Babies”. This genetic modification, genetically modifies the DNA of an embryo to achieve desirable traits amongst them. It changes an unborn babies development and future life. While it may seem that designer babies can be a positive life change, there are negative effects that outweigh, due to the fact that it goes against human nature; genetic probability, expectations, diversity, and religious prospects.

Although having a “designer baby” is not provided as a public possibility yet, the choice is in the near future. A designer baby is defined as a child whose genes were altered or selected to make sure a specific gene is attendant. Lee M. Silver, Princeton University microbiologist, predicts that the future will hold two human species, naturals and the gene-enriched (Preface to 'Genetic Enhancement of Human Abilities' n.p.). The gene-enriched refers to people with designer genes chosen by parents who have had the same done to them. This technology will first prevent birth defects and later diabetes and heart disease. As artificial genes develop to be common, the technology may be used to prevent drug and alcohol addictions, mental diseases, and eventually to create humans with synthetic characteristics (Preface to 'Genetic Enhancement of Human Abilities' n.p.). Parents will walk into a fertility clinic, choose the desired traits, and pay for the procedure. The fertility procedure to merge three people’s genetic material is currently being contemplated by The Food and Drug Administration (Smith 6).

Technology has made leaps and bounds over the past several years; it has come to have tremendous effects on how we live our lives; from transportation to how quickly we can access information. Recently, technology has begun changing the lives of children, especially infants. A new form of genetic engineering can genetically modify the DNA of an embryo to achieve specific or desirable traits; this is referred to as “Designer Babies”. This procedure will ultimately change lives, for better or for worse. While it may seem to most that designer babies are beneficial, they will actually cause more harm than good.

Imagine a future where parents never had to worry about their child being sick-- a future where technology allowed parents the ability to make a flawless child. That future is near, but is halted due to people’s fear of Genetically Modified Babies, which is “a biologically radical technique referred to by terms including ‘mitochondrial replacement,’ and ‘nuclear genome transfer,’ [these techniques] would produce modifications in every cell of any resulting children” (Cussin and Darnovsky 16). This procedure takes the fetus’s cells and allows the doctors to manipulate the cells in any matter they want; then, the cells are placed in the women’s egg. Unfortunately, Genetically Modified Babies are “codified as [prohibited] in more than 40 countries and several international treaties” (Cussin and Darnovsky 16). In the United States, the FDA had a full day meeting on the subject matter. On February 2014, they discussed human modification and prohibited it (Cussin, Darnovsky 17). The idea of a “designer baby” may seem preposterous, but technology is making the concept attainable. In the United States, there are laboratories that have the technology to reach such a goal, but are unused due to the FDA’s law; however, if “nuclear genome transfer were allowed, [the laboratories] could be used for any purpose” (Cussin and Darnovsky 17). America should allow gene manipulation in babies because it is inhumane to let innocent babies suffer from diseases and disorders that can be

Technology has had a huge affect on us humans in how we live our lives starting from anywhere between how we come up or find information to how we have the ability to travel the world. Technology seems to slowly be used for more and more lately, It’s important for us as humans not to overuse or abuse the technology we were given because it may have a negative effect on society and the lives of our loved ones. We have come across a new system of genetic engineering known as “Designer Babies” which genetically modifies DNA to set a goal of creating enhanced traits for the babies to grow up with. What people need to understand is that this expensive process can ultimately change their life. What may seem beneficial

For many years, the idea of being able to design and choose your children has long been a topic of science fiction. But rapid progress in genetics is making the idea of ‘designer children’ possible. A designer child is a baby whose genetic make-up has been selected in order to eradicate a particular defect, or to ensure that a particular gene is present. This can be used to improve the health of the baby, or enhancing particular genes to make the child achieve better in a particular area. These babies are also described as genetically modified, where the child contains genetic material that has been artificially altered so as to produce a desired characteristic. Despite the seemingly beneficial results, there are many negative as well as positive aspects to this new technique.

Designer babies are babies whose DNA has been modified to include and exclude certain traits. One such example is CRISPR-Cas9, a new technology, giving scientists the ability to control the genetic structure of human cells and use to create designer babies (Sas & Lawrenz, 2017). Additionally, what makes this gene editing attractive is the ability to locate, modify, or even remove deleterious gene diseases (Otieno, 2015). Gene editing might be beneficial to bring a child into this world without extra challenges such as deformities, genetic defects, and illnesses yet, there are serious concerns over this practice. Ultimately, not only is gene editing both difficult and expensive to achieve, but it is also an unreliable way to change natural order

How does it sound to walk into the doctor’s office, choose what attributes you want your baby to have, and then having that exact baby 9 months later? Although this may seem quite harmless to most, the negative effects of designer babies are tremendous: the lack of diversity in our population, violation of a specific set of laws designed to protect humans, going against Christian views, and even destroying the roots of human nature. With genetic engineering biotechnology, such as Clustered Regularly Interspaced Short Palindromic Repeats (or CRISPR), new and unique altercations are being done to revolutionize many aspects of our lives. Along with astounding benefits that can come from these biotechnologies, many people have come up with crazy ideas, such as these designer baby ideas, that could be potentially harmful to our society.

In this TED talk, biologist and geneticist, Jennifer Douda, presents a way to edit our DNA with the use of CRISPR technology. This technology allows scientists to change the DNA within our cells that could ultimately allow scientists to cure various genetic disease such as sickle cell anemia, Huntington’s disease and cystic fibrosis etc. The way this technology works is that the Cas9 protein seeks foreign DNA, and precisely cuts that DNA out and eventually degrades it. After the mutated DNA is removed from the double helix, the cells detect the broken DNA double helix, and repairs it by pasting its ends together via a tiny change within the sequence of the DNA, or cells may simply introduce a new sequence of DNA at the site of the break,