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Cats And Dogs And The Domestication Of Cats And Animals

Decent Essays

Primarily, biomedical research is conducted to discover ways to treat and prevent illness in humans and animals1. Both cats and dogs have a close semblance, anatomically and physiologically, to humans and they contract a number of similar pathologies that make them useful for this exact purpose. However, the domestication of cats and dogs in western society provides many with bias, and emotive, opinions regarding their use for research; few of which are based upon facts. As the public are major beneficiaries, it is important to consider both sides of the argument when using cats and dogs for biomedical research.

Through research on cats and dogs it is possible to understand certain diseases and their development in greater detail and therefore provide help worldwide for those who are in pain or suffering. Cats are subject to both genetic and neurological diseases that show a close correlation with those exhibited in humans – a critical example being feline immunodeficiency virus (FIV), which simulates HIV-1 infection in humans. Research into FIV has led to the development of the primary drug treatment2 for the 36.7 million HIV/AIDS sufferers worldwide3. Cats also have relatively long life spans4, leading to a similar form of Alzheimer’s disease to humans, providing useful treatments and cures5.

Dogs are also susceptible to several natural diseases that are homologous to humans. They have the advantage of “a unique population history of around 9000 generations with a unique breed structure of more than 400 genetic isolates” (Karlsson and Lindblad-Toh, 2008)6 which sets them apart from many other species used for research. The canine cardiovascular system is similar to that in a human, both in size and function7, enabling identification and treatment of mechanisms associated with cardiac diseases8. Other than humans, dogs are the only mammals with an extensive genetic diversity, long life span and large size which have enabled development of hematopoietic cell transplantation9, an important medical advance for those suffering with diseases such as leukaemia and lymphoma10.

There are, however, obvious barriers when comparing cat and dog models to diseases in humans. Species differences mean that not all

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