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Chronic Psychological Stress: A Case Study

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Chronic psychological stress is associated with the body losing its ability to regulate the inflammatory response. The inflammatory response is the body’s defense mechanism that protects it from infection and injury. Inflammation is partly regulated by the hormone cortisol and when cortisol is not allowed to serve its function the immune cells become insensitive to cortisol's regulatory effect. Prolonged stress alters the effectiveness of cortisol to regulate the inflammatory response by decreasing tissue sensitivity to the hormone. Unchecked inflammation is thought to encourage the development and progression of many diseases leading to a greater risk for depression, heart disease and infectious diseases.

Professor Cohen used the common

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