The Effect Of Stress On The Immune System

Immune System: When people are under intense stress for a while, their immune systems may become dysregulated, leading to lower functioning of important white blood cells called lymphocytes and to increased production of C-reactive protein (CRP), a protein that spreads throughout the body and causes inflammation and various illnesses. Some studies suggest that immune system dysregulation of this kind may help produce depression.

They have also found that there are strong links between prolonged stress and disorders, mentally and physically. Kiecolt-Glaser et al 1995 also carried out research into the relationship between Stress and the Immune System. Kiecolt-Glaser et al 1995 = == ==

When put under stress, both humans and baboons have cortisol and adrenaline found in their blood. These hormones are critical for survival, and other physical changes in the body such as a racing heart, increased blood pressure, and quickly responding muscles are all present when the body is put under stress. However, in regard to humans, these same physical responses can occur when the body is not in a life in death situation. Instead, it is common for psychological stresses such as public speaking, taking a test, paying taxes, or driving a vehicle to invoke the same physiological responses as someone in a critical situation. This can be unhealthy for the human body, as many people can get worked up over multiple stressors in one day,

The biological purpose of the stress response is to help the body to survive either some sort of attack or a serious illness like a stroke or heart attack. During the stress response glucocorticoids divert the bodies energy to the areas necessary for survival like the muscles and the brain and it shuts down the areas that are not necessary for survival like the digestive and immune systems (Sopolsky, 2009). Chronic Stress in this context, is to experience this physical effect on regular or long term basis. This has become a public health issue for humans because we experience this chronic biological response on a too frequent a basis for psychological reasons (Stress, 2008).

The video “Stress Portrait of a Killer” was enlightening. The correlation between each individual’s placement in the hierarchy and their level of stress was not surprising. In fact, it made a great deal of sense. When one is on the lower end of the spectrum, it is a reasonable to anticipate higher levels of stress than when one is at the higher end. The latter, has more control over what is happening in their lives which in turn eliminates that stress. What I found most interesting, is that stress lowers the body’s immunity. I had no idea that the brain cuts non-essential systems like the immune system when stress is present. I found this fact fascinating and rather concerning. For as long as I can remember, I have been very susceptible to

Most studies of the relationship between stress and the immune system have focussed on acute(i.e. short lived) stressors and have found a decrease in immune cell function.

Initial response to stress activates immune systems; prolonged stress weakens the immune system making you more susceptible to getting sick.

The agents can be bacteria, viruses, fungi and parasites. Therefore, the body has two types of cells that help us fight infectious agents which are Lymphocytes and monocytes. These are known as white blood cells and the two types are T cell and B cells. So basically, these two cells fight to help the body fight off any infectious agent invaders. Therefore, these cells are extremely important for our bodies protect us. But how does this relate to stress well the chapter shows a logical explanation where it basically states that stress may be inhibiting the immune functions. But that is not the case the immune system is actually enhanced. The problem is with stress we create glucocorticoids, which in fact kills lymphocytes. This is what helps destroy the infectious bacteria, therefore with it being destroyed it will destroy the immune system. In relations to what we have learned in class was how high levels of Glucocorticoids impact the body in a negative way. Therefore, having high levels of Glucocorticoids for an extended of time signifies that one is highly stressed impacting many things such as the immune system in this

Viewed from an evolutionary standpoint, in early times stress caused the stimulation of the sympathetic nervous system resulting in an outpouring of the hormones epinephrine, norepinephrine, and glucocorticoids that were essential to the life-preserving fight or flight reactions of primitive man (Anthony 1988). However, the nature of stress for the individual today is different. It is only occasionally and unexpectedly that one is confronted with overwhelming, life-threatening stresses. Present stresses arise from everyday stresses of work, finances and school. The problem is that the body still continues to respond in the same fashion as primitive times. This makes the large release of hormones very harmful. They can cause an increase in blood pressure, damage muscle tissue, lead to infertility, inhibit growth, damage the hippocampus and suppress the immune system (Carlson 1994). It is therefore, important that individuals learn to control the stresses in their lives. The more detrimental coping behaviors will cause a larger change

Stress can get bad enough to where it starts to affect your body system. Things like depression, heart attacks, diseases, rashes and a low immune system can all occur to people dealing with stress bad enough. The number of common signs and symptoms is outrageous and is depressing to see that there are so many people dealing with this and how it’s such a common thing in this world. On stress.org, they talk about the different body systems and how they’re affected. The nervous, musculoskeletal, respiratory, cardiovascular, endocrine, gastro and reproductive systems are all affected in some way and in many ways to say the least. If your stress ever gets so bad, I consider seeing a doctor or specialist seeing how dangerous this can get.

Getting sick is another negative factor of being overly stressed. Chronic stress compromises your immune system and stress hormones affect the body’s ability to fight off illness due to the fact that thymus’s ability to stimulate and coordinate the white blood cell activity.

When we experience stress, how is the endocrine system activated? How does it become deactivated?

Chronic stress can also interfere with the body’s immune system directly through hormonal changes. Glucocorticoids-a hormone

Humans experience similar dramatic physiological stress responses as other species. That is to say, the physique response to a stressor prepares the body for rapid physical action (fight or flight). More rarely, as Rudinger (1988) argue, sitting paralysed by fear may constitute another response to stress. The fight or flee stress response involve extremely rapid, virtually immediate, changes within the muscular systems and organs (Pinel, 2006).

      Stress can cause many things that affect a healthy body.  Stress causes quick yet shallow breathing in which case, the body's cells are being deprived of oxygen.  Stress will increase cholesterol levels and can also cause indigestion, heartburn, a decreased sex drive, and also arteriosclerosis (the hardening of the arteries).  While these symptoms may seem minimal, stress can decrease the activity of white blood cells.  Since the white blood cells fight off sicknesses and diseases, the immune system is affected by stress and can make the body more susceptible to colds, viruses, flues, and diseases (Morrison 2).