Chronic Traumatic Ptsd ( Cte )

1522 Words Apr 12th, 2016 7 Pages
Introduction Chronic traumatic encephalopathy (CTE) is the current understanding of a form of progressive dementia that used to be classified as punch drunk syndrome in boxers as early as the 1920s all the way up until the 1950s and 1960s 6. What makes this disease so elusive is its difficulty to be detected until postmortem autopsies are conducted 6. As a consequence, several professional athletes experiencing head injuries were unaware of the fatal consequences of participating in sports involving major blows to the head like boxing, hockey, and second most notoriously, American football 3,6. In fact, clinicians have noted a positive correlation between time spent playing football and pathological CTE in the postmortem analysis of brain tissue in ex-football players 2. Other causes of traumatic brain injury (TBI) that could lead to CTE through events unrelated to sports include assault, vehicular mishaps, and even domestic violence 1.
Active areas of research include identifying the origin(s) of pathology for CTE 3, imaging techniques to find microstructural changes in the brain that can give indication to progression of the disease 6, utilizing tau immunohistochemistry to identify possible protein deformations contributing to the disease 1, and identifying the variability associated with the progression of the disease 4.
Pathogenesis and Pathophysiology of CTE
The origin of the pathophysiology of CTE can be quite complex, so other forms of traumatic brain injury have…
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