Familial Mediterranean Fever Introduction Familial Mediterranean Fever (FMF) is a very rare disease that tends to attack individuals of the following ancestry: Turkish heritage; Arab heritage; and Sephardic (non-Ashkenazi) Jewish heritage. This paper delves deeply into what is known about the disease, what remedies if any are appropriate, and other ramifications of the disease. What is Familial Mediterranean Fever? Familial Mediterranean Fever is a disease that is inherited and when it hits a person it brings with it "…recurrent attacks of fever, inflammation of the abdominal lining (peritonitis)" along the following health issues: pleurisy, swollen joints including arthritis, and a rash on the ankle that is very typical of an FMF attack (www.genome.gov). The Genome web pages say that FMF hits roughly 1 in 200 people of the ancestry mentioned in the Introduction; the disease clearly has Mediterranean roots and FMF seems to attack Spaniards, Greeks, Japanese, Northern Europeans, Italians and Ashkenzi Jews (www.genome.gov). When was the First Known Attack? According to a book by Gordon Charles Cook, the first description of an attack that was later determined to be Familial Mediterranean Fever was discovered in 1908. It was a discovery of "…recurring attacks of a peculiar nature," Cook explains (Cook, 2009). It was a 16-year old Jewish schoolgirl without "…special neurotic inheritance" who suffered from severe abdominal pain, Cook writes. The pain consisted of
The concept of a “carrier” first emerged with typhoid fever with Mary Mallon in 1907. Mary Mallon was a working as a cook in her employer’s household, Charles Henry Warren, in New York. Working as a cook allow the bacteria, Salmonella typhi, to be transmitted to the household members through the food she was handling. George Sober, a sanitary engineer, was brought in to find the cause of illness and had proposed that it was the ingestion of freshwater clams. This was later disproven by the questioning of the infected individuals having denied they had eaten the clams. Sober then moved his suspicions onto Mary Mallon, believing she was spreading the disease as a carrier. This was a new concept at the time and was not readily accepted, especially
Yellow fever is a deadly disease caused by a viral infection that is transmitted through the bite of an infected mosquito. Although it is found to be most common in males in their early 20's, yellow fever can affect any sex, race, or age. Since yellow fever is carried by mosquitoes, it is most often found in areas such as Central America, the northern half of South America, and Central Africa where mosquitoes are abundant. The reason why it is found so often in these
The doctors that came up with the treatments for this disease were French and American. The American and French doctors were similar in many ways. They both treated yellow fever and they were both curing in the same city ,Philadelphia.
The Doctors were the only people who could treat this bilious fever. The doctors had some similar tactics or ways to treat. First of all, both of the doctors truly cared for there patients. Evidently, in the second to last paragraph, it read that “the “French Cure” is keeping their patients alive” and for the Philadelphian it reads “they had always cared for their patients”. The second comparison I can make is to feed the patient's lots of liquids. For example, in paragraph 3 it says for Philadelphian “Drink wine and take cold baths” and for French is reads “Dr. Deveze advocating giving patients plenty of fluids”. Last but not least, the two doctors (French and Philadelphian) both give out pain relievers. In paragraph 2 it says, “Take a salt of tartar in lime juice and barley water and laudanum (pain killer)” and in paragraph 12 it also says, “ Pain medications and fever-reducing medications were used to relieve symptoms of fever and aching”.
They only showed certain symptoms to be a disorder or disease such as ergotism. Which would not be enough evidence to claim that it was the cause. “There were none of the constitutional, residual effects typical of ergotism, such as weakness, strictures, or dementia. The afflicted were hale and hearty.” (Spanos and Gottlieb, 1976).Despite the seizing and weird pinching or burning, they displayed no other signs of being unhealthy. Or having any other mental defect. “The ages of the afflicted were older than other epidemics.” (Spanos and Gottlieb, 1976). For other epidemics for the common theory of ergot, they were much older than past breakouts. Which doesn’t add up. “Symptoms of the afflicted could be turned on and off, depending on the audience.” They’re weird behavior would start and act up at odd times for it to be a mental disability or even a sickness such as ergot. As usually the problems are
The first disease that stood out was hemochromatosis. This disease messes up how much iron the host’s body is producing, and how it 's distributed. Usually, hemochromatosis builds up iron to dangerous levels that can harm almost any part of the host body, and may lead to death. Some symptoms include physical difficulty, an “achy feeling”, and pain in joints. Hemochromatosis was discovered to have most likely originated with the Vikings and the Vikings kept spreading the disease as they expanded their territories over Northern Europe. Though at first, hemochromatosis wasn 't diagnosed properly (nowadays, we can diagnose hemochromatosis through blood tests), it was being treated by blood-letting (which actually did and still does work). After a recent study,
First characterized as a mild sickness characterized by adenopathy, a rash, and hardly a fever, George Maton did not think much of the disease in 1814. However, later on, a scientist by the name of Veale gave it the name of rubella in 1866. Rubella (German Measles) attracted hardly any attention before 1942, when it was discovered by Norman Gregg that birth defects were being linked with maternal rubella in the first trimester. It was until 1962 that the full gravity of rubella embryopathy remained a mystery. In that year, two different groups by the names of Neva and Weller; and Parkman, Buescher, and Artenstein; isolated and clarified rubella in a single tissue culture. (1) Utilizing the newly developed tools of the virus laboratory, several
In the 1970’s, doctors were receiving patients who were having odd symptoms. The symptoms were swollen knees, paralysis, skin rashes, headaches, and severe chronic fatigue (“History of Lyme Disease”). In the 1980’s a doctor named Willy Burgdorfer was
Introduction: Over time we come to realize a lot of things we have to live life with right under our nose and right at our door step. one of the worst and on going things we have to deal with are Viruses. there are a wide range of different types of viruses, from ones that can kill you ,to ones that we don't even know we have, some are contagious , and some are not, and also the dreaded air borne viruses. One virus that is not commonly mentioned is Valley Fever.
Lyme disease was unknown to people in the early 1970s and may still be unknown if not for two mothers in Lyme, Connecticut. The mothers both noticed their kids and others in their town had the same symptoms and started trying to figure out what was wrong. The medical field began studying the groups symptoms to try and find a cause. By the mid 1970’s the new disease was called Lyme but no one knew what was causing it. In 1981 scientist Willy Burgdorfer who studied Rocky Mountain Spotted Fever started to study Lyme disease. He found the cause of the disease in a deer tick. He had discovered a bacterium called a spirochete. In 1982 the medical field named the spirochete Borrelia burgdorferi in honor of his discovery.
The symptoms of streptococcus pyogenes have been recorded by scientists and historian for many years. Hippocrates (known as the father of medicine), was the first to records symptoms of scarlet fever and “the flesh-eating bacteria; two infections that group A Strep are now known to be involved in. Pasteur was the first to isolate the chain-forming bacteria and Rosenbach named it.
An analysis of bothersome mysteries that were left behind in the short story “A Fever in the Blood”: it being the untold reasons of why the Marchetta’s both attack Mr. Strang biting both of his ears off, his lack of customers, and his imperative loss of hearing. The strange blood curdling event when Johnny Marchetta latched his jaws onto Mr. Strang’s right ear in the alleyway for no apparent reason. He seemed to be like a rabid dog gone crazy for the thirst to bite a human, immobilizing him to finish him off. The thoughts that could be going through Mr. Strang’s could be endless; he did not know the man or the reason of led him to attack his ear.
The disease was first noted in 1786 by Caleb Hillier Parry 1755- 1822, physician from General Hospital, Bath, England. His account was published posthumously in 1825.
A 49 year old Afro-Cuban male with a history of chronic alcoholism and hypertension presented with a three day history of fever (106ᵒ F), change in mental status, and body aches in August, 2016. On admission, he was febrile 103.1ᵒ F, with a heart rate of 137 beats per minutes, blood pressure of 156/79 mm of Hg, and respiration rate of 32 breaths per minute. The patient’s laboratory results on admission included white cell count 9.2 x 103/microL, platelets 71 x 103/microL , PT 28 seconds, PTT 43 seconds, INR 2.62, albumin 3.1, Tblb (total bilirubin) 13.6 mg/dl , AST (aspartate transaminase) 133, and ALT (alanine transaminase) 56. Lactic acid was 6.2 mmol/L, and blood alcohol level checked the next day was less than 10 mg/dl. In addition, he
Ethnicity can provide individuals with wonderful traditions and celebrations of one's heritage. However, for some Ashkenazi Jews, ethnicity brings them much more than they bargained for: a rare condition causing a wide array of liver, lung, spleen, bone and bone problems. Ethnicity brings them Type I Gaucher Disease. Type II and Type III are the two other forms of this rare genetic condition, and can occur at equal frequencies in all ethnic groups. Gaucher disease was first described in 1882 by Doctor Philippe Charles Ernest Gaucher from France (2) . Type I , the most frequently seen form of the disease, can affect people of multiple ethnic backgrounds. However, its prevalence is greatest