Endodontic Therapy

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Results: We found 20 articles that matched our inclusion and exclusion criteria and 7 of them lake the clear description of the outcomes and method so we excluded them. The Clinical Indications for Pulp Regeneration: The pulp of teeth repeatedly undergoes irreversible disease caused by caries, trauma, congenital abnormalities, or as a complication of previous dental procedures (7). Endodontic therapy aims to an effective and specific treatment for the irreversibly diseased pulp, with preferable short- and long-term outcomes (7,8). However, endodontic prognosis studies have conclusively shown that the presence of pre-operative infection, generally determined by lack of response to vitality tests and the presence of a radiolucent periapical lesion, reduces the long-term outcomes of treatment by about 15-20%, compared with cases with vital pulp (8). While the prognosis of endodontic treatment in these cases remains favorable, the situation is more complicated incases with young immature teeth. Root canal instrumentation, disinfection, and sealing are more technically difficult to performing these cases (9-11). Perhaps more importantly, the tooth remains weak and is therefore susceptible to fracture due to functional stresses or minor trauma, an outcome that has been determined to range from 28-77%, depending on the degree of root maturation (13).This distinction is important, given that calcium hydroxide is rarely used long-term today, because of the availability of apexification techniques that rely on these of…show more content…
They maintain their self-renewal, and produce pulp-like tissue, bone-like tissue, odontoblast-like cells if transplanted in animal models, which indicates their important role in regenerative cell based therapy
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