Epilepsy Drug Therapies

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This paper will focus on the history of epilepsy, the causes of the disease specifically its genetic link and the evolution of drug therapies. My interest in this topic stems from working with people with developmental disabilities in a group home setting, many of whom suffer from seizure disorders. I understand that the disease carries a stigma and many people still hide that they have the condition which why it’s important to educate people about it.
According to Lewis, Dirksen, Heitkemper and Bucher, in the United States, it is estimated that more than 3 million people have active epilepsy, with 200,000 new cases diagnosed each year (2014, p. 1419). This is why it is an important disease to understand. According to Lewis et
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He had major developments in the study of epilepsy. First, he pioneered the idea that epilepsy did not just involve convulsions but also affected other bodily functions. Secondly, according to Millett, Galen integrated the four basic humors of the human body with newer concepts of brain structure and emphasized the importance for various psychological structures. Thirdly, Galen came up with the first ever classification of seizure disorders, idiopathic and sympathetic. Lastly, he identified that the initial symptoms of a seizure, such as numbness, tingling and abnormal movements resulted from the propagation of abnormal “pneuma (a life sustaining substance that was created in the lungs and acquired “psychic” properties in the cerebral…show more content…
This period was not without supernatural beliefs, so Epilepsy existed between these two worlds. However, researchers proved that theories of the effect of Epilepsy on brain function were more than just superstitious beliefs. Several different types of seizures were seen in this period. English Neurologist John Hughlings Jackson best known for his research in Epilepsy, discovered “a correlation of these focal motor seizure onsets and their associated brain lesions in laying the foundation of modern epileptology.”(392). in 1772, Swiss Neurologist Samuel August Tissot gave the first detailed definition of absence seizures which were mainly seen in children. Patients with chronic epilepsy were taken to clinics or asylums for observation which brought awareness to the variety of seizures and by the second half of the 19th century, there were a number of dedicated facilities built to care for people with Epilepsy. In these facilities, terms such as absence, petit mal and grand mal were introduced which are still used to date. (392). It was also in this time period that the first treatment, bromide, was discovered by Charles Locock in the late
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