Essay On Macular Edema

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The current study was conducted to investigate the changes in choroidal thickness within the macular area in eyes with various types of diabetic macular edema, by comparing the measured values with those of healthy normal subjects and of subjects with diabetic retinopathy without diabetic macular edema and to correlate the sub-foveal choroidal thickness measurements with the central macular thickness. Patients and methods: A prospective, nonrandomized, observational study was conducted to evaluate the central macular thickness (CMT) and the choroidal thickness (CH-T) in eyes with treatment-naïve diabetic macular edema. One hundred forty two eyes of 96 subjects were enrolled in the study. The current study included eyes of patients with…show more content…
The studied eyes were chosen if the eye met both the inclusion and exclusion criteria. If both eyes of the same subject were qualified, both were selected. Central Macular thickness measurement: The fast macular thickness OCT scan protocol was performed with measurements from 20 x 20-degree raster scans (consisting of 25 scans). The mean thickness of the central 1-mm zone of the 1, 3, 6 mm Early Treatment Diabetic Retinopathy Study (ETDRS) grid thickness map was measured by the program incorporated in the Spectralis OCT software. Choroidal thickness measurement: To obtain the choroidal image, Heidelberg Spectralis SD-OCT-EDI button in the Spectralis software was used. The white-on-black image color was used for better contrast between the choroid and the sclera. The choroidal thickness was measured manually, using the caliper tool in the Heidelberg Spectralis OCT software, as perpendicular line, from the outer portion of the hyperreflective line corresponding to the RPE to the choroidoscleral interface. The choroidal thickness was measured from vertical and horizontal scans centered on the fovea. The CH-T measurements were obtained from the subfoveal and parafoveal areas at an interval of 500 μm up to 1500 μm from the center of the fovea (nasal, temporal, superior and inferior). All measurements were performed at the same time of the day from 1PM-3PM for the diurnal variation of the choroidal thickness.

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