Hakaru Hashimoto Research Paper

Hashimoto’s Disease is a chronic Lymphocytic thyroiditis also known as autoimmune thyroiditis. It is due to chronic inflammation; the disease is a failure of the thyroid gland. Hashimoto’s disease is the most common inflammatory disorder of the thyroid and the leading cause of having hypothyroidism. The name of the disease came from a Japanese surgeon named Hashimoto Hakaru. Hakaru first described the chronic disease as Struma Lymphomatosa in a pathology report in the year 1912. Hashimoto’s Disease is a genetic trait and found to be more common in women then in men; and commonly found in women between the ages of thirty to fifty years of age. Hashimoto’s Disease can be found in children too; in the first-degree relatives that have the disease is found to have an increased incident.

Eerikki Harou was a jarl born in a village in Scandinavia which is now modern-day Aarhus, Denmark. He was nicknamed “Eerikki the Bonesmasher.” Eerikki also was a pagan who worshipped warlike gods such as Odin, the god of war and death. He was known for leading numerous pillages against monasteries in Anglo-Saxon England. Sources say he and his men usually ambushed the monks, killed them swiftly, looted everything valuable out of the monastery, and left the site with many bloody corpses in his trail. His brutal and intuitive tactics caused fear among all people of Europe. This lead to a new prayer in many churches: “Save us, O God, from the fury of the Northmen.” In 878 AD, Eerikki fought with the Great Heathen Army led by Guthrum in the Battle

Primary causes include iodine deficiency and the autoimmune disease named after Hashimoto (NIDDK, 2013). As stated earlier iodine deficiency occurs in countries that do not have iodine in their water supply. Hashimoto’s disease occurs when there is a problem with the immune system that causes white blood cells to accumulate on the thyroid gland that results in loss of thyroid function (NIDDK, 2013). Other causes of primary hypothyroidism include: thyroidectomy, thyroid ablation, inflammation of thyroid gland, not enough medication and some medications (NIDDK, 2013). Causes of secondary hypothyroidism include: pituitary cancer, Sheehan syndrome, injuries of the brain, brain cancer, radiation, administration of growth hormones, and brain hemorrhages (NIDDK, 2013). The numerous symptoms of hypothyroidism include: weight gain, decreased activity, fatigue, constipation, intolerance of cold conditions, pain in the muscles and joints, dry, course hair with or without hair loss, depression, problems with memory, bradycardia, problems in women with menstruation (NIDDK, 2013). People may experience any of these symptoms. People that have hypothyroidism for prolonged period of time have symptoms that may include: loss of taste, hoarse voice, edema, slow speech, thin eyebrows and thick skin (NIDDK, 2013). Diagnosis of this disease is not always easy because these

Hashimoto Thyroiditis also known as Hashimoto’s disease named after Hakarum Hashimoto back in 1912, is an Autoimmune Lymphocytic infiltration of the thyroid gland by antithyroid autoantibodies. It is highly likely for a person to develop Hypothyroidism as a result of the autoantibodies attacking the thyroid and keeping the thyroid from producing the amount of hormones our bodies need. As stated in the Ear, Nose and Throat Journal “Approximately 5% of the general population has hypothyroidism, with Hashimoto thyroiditis the most common cause.”(2) The journal also goes on to say how women are affected disproportionately with a ratio of 10:1. While there is not a definite cause of Hashimoto’s it has been researched that majority of people who have the disease have a family member who also suffer from thyroid disease, suggesting that it could be genetic.

Hashimoto's thyroiditis is an autoimmune disease where the body sees the thyroid tissue as an antigen, and therefore attacks the tissues which results in inflammation and eventual destruction of the thyroid gland (Burkhart, 2013). Hypothyroidism (an underactive thyroid gland) is one of the first clinical symptoms that lead doctors to diagnose Hashimoto’s (Mayo Clinic Staff, 2016). Other symptoms can include fatigue, weight gain, hair loss, and joint pain, among other things. As diet in America gets worse, autoimmune disorders rise. The food we eat is negatively affecting our bodies, so much so that they are becoming inflamed and rejecting those foods in the form of allergies. Nutrition plays such a vital role in

Other symptoms may include constipation, dry skin, and thinning hair. A masklike expression and puffiness in the face is noted with hypothyroidism. The voice may be low-pitched and hoarse. Some women have reported irregular menses also. Numbness and tingling unrelieved by position changes, and edema in the extremities is reported. The patient I observed with hypothyroidism complained of fatigue and tiredness. She kept her room air warm to prevent chills. Her face presented with puffiness in the cheeks and around her eyes. She had slight non-pitting edema in the distal portion of her lower extremities and her ankles. She also mentioned working to keep her weight healthy with a healthy diet because it was easy for her to retain

It can go undiagnosed for many years causing mental, emotional, and physical stress on individuals and the people around them. The cause of hypothyroidism is primarily due to insufficient TH production from the thyroid gland. This pathology of the thyroid gland can be a problem from birth or develop from iodine insufficiency, autoimmune disorders, or even iatrogenic interventions. The symptoms of hypothyroidism change from individual to individual. While some objective findings may be noticeable right away other subjective symptoms require the use of health assessment skills. Once a person has hypothyroidism they cannot be cured and if not treated hypothyroidism can eventually lead to death. However, proper use of hormone therapies allows many individuals who suffer from hypothyroidism to drastically diminish the symptoms and signs of the disorder and to live a healthy life with normal life expectancy. More research is needed to identify the appropriate guidelines for treatment of subclinical hypothyroidism and how these individuals can reach optimal health

The thyroid is unique in a way that it absorbs iodine from blood. The hormones secreted from the thyroid gland are used regulate metabolism in the body. These thyroid hormones control the conversion of absorbed nutrients into energy that is used throughout the entire body. By doing so, these hormones are responsible for controlling metabolism in cells from all parts of the body. If a dysfunction of the thyroid gland were to occur, this could cause a change in the amount of hormones produced and secreted by the thyroid, which would then in turn, affect the body’s ability to regulate the metabolic

V.G.’s current symptoms of fatigue, difficulty concentrating, a weight gain of 10 pounds and irregularity noted to her menstrual cycle along with lab findings of an elevate TSH and a decreased T4 level are consistent with hypothyroidism. The condition is more common in women and is associated with an increased risk of heart disease (Woo & Wynne, 2012). Individuals with hypothyroidism present with clinical findings which may include bradycardia, anemia, dyspnea, decreased appetite, constipation, weight gain, hyperlipidemia, dry skin, brittle hair, difficulty with reproduction, memory impairment, hearing loss and changes in vision (Woo & Wynne, 2012). These clinical manifestations are secondary to changes in metabolic demands and blood flow secondary to the thyroid hormone (Woo & Wynne, 2012). With this wide array of potential symptoms V.G.’s physical exam would involve a thorough head to toe exam carefully evaluating her current cardiovascular status including blood pressure, heart sounds, rhythm and rate with perfusion assessment to identify bradycardia and risks of heart failure. In addition, a careful examination of her neck would be

Composer Hans Hansen once said, “It takes nothing to join the crowd, but it takes everything to stand alone.” To be successful, one must do what they want, not what the rest of society wants. Shigeru Miyamoto is a Japanese concept artist born in 1952. He entered the field of video game design in hopes of expressing his inner artist (“Shigeru Miyamoto,” 2004). Miyamoto created some the most popular video game titles of the current age, innovating ways to overcome not designing games in the modern style of game design, and illuminating the world by progressing recreational entertainment through art.

There are mainly two types of hypothyroidism in adults, primary hypothyroidism and secondary (central) hypothyroidism. In primary hypothyroidism, the thyroid tissue gets affected and losses functionality leading to diminished production of TH. Some causes of primary hypothyroidism are endemic iodine deficiency, autoimmune Hypothyroidism (Hashimoto’s thyroiditis), loss of thyroid function due treatment of hyperthyroidism, medications and radiation therapies around head and neck. On the other hand central hypothyroidism is caused by pituitary malfunction and hypothalamic malfunction. Congenital hypothyroidism occurs in newborns where they lack the presence of thyroid gland or has genetic disorder in TH synthesis. If not identified and treated this can severely effect child’s

Hashimoto’s disease or also known as chronic lymphocytic thyroiditis is directly correlated to the thyroid gland: meaning that it is autoimmune deficiency disease. The thyroid is apart of the endocrine system

Hypothyroidism is the most widely recognized clinical disorder of thyroid function. It is frequently caused by a disorder of the thyroid gland,

Hashimoto’s disease is also known as chronic lymphocytic thyroiditis-or- Hashimoto’s Thyroiditis. This disease was named after the Japanese doctor; Hakaru Hashimoto.5 This is a condition where your immune system creates antibodies that can damage your thyroid gland. The autoimmune disease creates inflammation with an increase in destruction and fibrosis of the thyroid gland. Your thyroid is a gland in your neck that secretes hormones.4 Hashimoto’s disease can sometimes lead to an underactive thyroid which can result in hypothyroidism. This is also the most common cause of hypothyroidism. 2

My mom has had hyperthyroidism because she has Hashimoto’s disease and three nodules on her thyroid. She got very sick and lost a lot of weight, lost a lot of hair, had to go to the ER for anxiety attacks. The extra hormones made her body shake, and gave her headaches and stomach aches. The doctors scheduled surgery to remove her thyroid. We ended up moving so she didn’t get the surgery, but now she is taking iodine and some other pills to feel better. She has Hashimoto’s disease so the symptoms may come back later but for now she is okay. Thyroid problems are very common but most people have the opposite problem called hypothyroid disorder, which is where the thyroid doesn’t make enough thyroid hormone. Hyperthyroidism is harder to treat and has many negative consequences, but it’s not as common. As you can see Hyperthyroidism can be very painful and