square values were 0.920239319 and 0.846840404 respectively. As illustrated in table 5 the five highest predicted inhibitory activities of un-synthesized phenylguanine analogues were pentafluoroethyl, phenoxy, pentafluorothio, phenylazo, trifluoromethylthio. This was due to their balanced values of each of the parameters allowing them to not only cross the phospholipids bi-layer but also dissolve in the hydrophilic bloodstream and affects its targeted site. Introduction The Herpes simplex virus or HSV is a member of the herpes virus family. HSV
This can be contacted from another person after direct skin-to-skin contact, mouth contact, or sexual contact. When the virus is first caught, it does not always show up on the skin, but can lie dormant within special parts of the sensory nerves. Later in life, the virus can become active again and appear as herpes simplex on the skin. Areas which are most commonly affected by herpes simplex are the lips (as cold sores) and the genital area (as genital herpes).
Herpes Herpes is one of the common of more than 30 different sexually transmitted diseases (STD’s) in America today. Herpes is an infection that is caused by one of two closely related viruses, herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). Both of which are very easily caught, have similar symptoms, and can occur on different parts of the body. Even though it is most common to see the virus HSV-1 appear as oral herpes and to see the virus HSV-2 appear as genital herpes.
Introduction I. (Attention Getter) The Center for Disease Control reports that 100% of sexually active men and women contract genital HPV
Herpes, from the ancient Greek meaning to creep or crawl, is the name of a family of viruses of which herpes simplex virus 1 and herpes simplex virus 2 (HSV-1 and HSV-2) are the most serious human pathogens. HSV-1 is normally associated with orofacial infections and encephalitis, whereas HSV-2 usually causes genital infections and can be transmitted from infected mothers to neonates. Both viruses establish latent infections in sensory neurons and, upon reactivation, cause lesions at or near point of entry into the body.
HSV-1 is generally transferred from one person to another by kissing.... HSV-2 is usually transferred by vaginal intercourse or anal intercourse. Yet in the same way HSV-1 may invade the genitals and then trigger genital HSV simplex virus, HSV-2 will transfer from a single person's genitals to one other person's
REACTION PAPER ON HERPES
Advances in treatments and health care have made Herpes infection in the western world a chronic disease. Currently, quality and life expectancy of people with Herpes could be compared to that of many other people. However, changes in the social perception of Herpes have been less significant. Routes of transmission, its implications regarding the mandates of more traditional gender and their association in the social imagination to socially excluded groups are because of the stigma associated with infection and ground of discrimination in various
Communicable Disease: Genital Herpes Virus (HSV-2) Introduction Genital herpes is reported as a "common and highly contagious infection usually spread through sex." (WebMD, 2012) Herpes is an infection resulting from the herpes simplex virus-2 (HSV-2) which is similar to herpes simplex virus-1 (HSV-1) which is the virus that causes cold sores. Individuals infected with the herpes virus have recurrent outbreaks in fact 90% of individuals infected with the herpes virus report repeated outbreaks with some reporting only two outbreaks each year. However, some individuals report up to eight outbreaks per year with the herpes virus. (Shiel, 2011, p.1)
Herpes Simplex I & II Rigo Hernandez Period 4 3-5-16 Herpes simplex 1 also known as oral herpes, it's scientific name is simplex virus. Herpes simplex 1 is a bacterial disease. Herpes simplex 1 is passed with children if the parents carry it. This type can also be carried by kissing, drinking from the same cup from a person that carries it, and any other physical contact with someone that carries it. The cause of the disease can be found on/in the mouth. HSV-1 has a few types of functions: cold sores and/or fever blisters around the mouth and on the face. HSV-1 can be spread much faster when an infected person is having an outbreak. The disease can be spread to any age group, especially if you -have a weekend immune system, having multiple sex partners, being a female, having another sexually transmitted infections- this also goes for Herpes simplex 2 (HSV-2).
There is a old misconception Herpes Simplex 1 only infects "above the belt" by manifesting as cold sores. Herpes Type 2 was previously considered "below the belt" and caused genital lesions. However, the medical profession has found oral-genital contact can spread either, so that types of herpes have become virtually insignificant.
Herpes is an STD that can be caused by one of two viruses, Herpes Simplex Type 1 and Herpes Simplex Type 2. In the United States, herpes is quite common as every one out of six people ages 14 to 49 years old have herpes. You can spread the disease by having vaginal, anal, or oral sex with someone who has the disease, and getting into contact with fluids found in a herpes sore. Herpes has periods where you are really susceptible to spreading it and periods where you aren’t, and the symptoms one gets during these periods to indicate a flare up, such as itching and tingling, and sores are called Prodromal Symptoms. Between outbreaks, herpes can still be spread, and this is called Asymptomatic Transmission. Many people catch herpes from one who is infected during these periods and also by people who don’t know they are infected. If you recognize your symptoms, you are much less likely in spreading the virus when the lesions are present. To prevent spreading during asymptomatic periods and periods when you do have lesions, regularly using sexual barriers and condoms or avoiding sexual contact is advised. During flare ups, do not touch the sores, as you risk spreading the disease to other people and other places, and if you do, promptly wash your hands thoroughly with soap and water.
Herpes Simplex Viruses 1 and 2 Oates states that "the herpes virus [HSV1 & 2] is a roughly rounded particle, with its protein coat made up of a large number of hollow protein units. The whole is surrounded by a loose, 'baggy' envelope and measures about 100 nanometers ... “(p. 22). The herpes virus is transferred through body-to-body contact, most commonly when sores are present. However, the virus can be spread when there are no signs or symptoms of an outbreak. HSV usually infects the mucous membranes around the mouth or genital areas, but sores can form anywhere on the body. Once inside a living cell HSV takes over and the cell
The first thing to do with a situation like this would be to first find out all the needed information about the gene you can. The first important thing would be the size of the gene on the chromosome, because viruses only have a certain amount of DNA/RNA they can hold inside their virus particle. The gene is found on chromosome 20 and is 15,438 bp in length (NCBI). So, the only type of gene therapy vector that would be able to carry a gene that large would be the Herpes Simplex Virus. HSV has a carrying capacity of over 30kb, so this would more than fit the entire length of the gene in the virus particle. It also is a good fit because after looking up information on PRPc, because it is a cell-surface copper-binding glycoprotein expressed
Genital Herpes Facts The Sexually Transmitted Disease Genital herpes (to creep) is very common in most Americans especially adolescents. Genital herpes is transmitted through sexual contact and other physical contact with an infected person. Herpes is a viral infection caused by the Herpes Simplex Virus. Once a person is infected with the virus it stays in their body for life. Once you have contracted this virus it is easy to pass it on to someone else even if the virus is not active. The