preview

History Heartworms are a parasitic nematode of mammals and have first been observed in Italy in

Better Essays

History Heartworms are a parasitic nematode of mammals and have first been observed in Italy in 1626 (3). Later the parasite was introduced to the Americas by European immigrants leading to the earliest recorded heartworm finding in the United States in 1847 published in The Western Journal of Medicine and Surgery (3,5). In 1995 the intracellular Gram-negative bacterial endosymbiont Wolbachia, belonging to the order Rickettsiales, was identified to reside in the heartworms tissue (4).Today heartworm infections have been reported in all states except Alaska and the number of incidents are increasing at an alarming rate (5). Risk Factors Several types of mosquitos have been identified as the vector and intermediate host of dirofilaria …show more content…

Figure 1: Geographical distribution of heartworm infections in the U.S. in 2007 (5) Biology and Life Cycle Infection of mosquitos with dirofilaria immitis microfilariae occurs when the mosquito is feeding on blood of heartworm positive dogs infested with reproducing adult worms (5). Within the mosquito the microfilariae develops into a stage 1 larvae (L1) followed by molting into stage 2 and infectious stage 3 larvae (5). Stage 3 larvae migrate to the mouthpart of the mosquito and rupture the end of the labrum as the mosquito feeds on an animal to enter the new host in a drop of hemolymph via the bite site (5). Stage 3 and stage 4 larvae migrate between the muscle fibers of the host until young worms are brought to the lungs and heart by the host’s vascular system (5). Six to nine month after infection dogs develop a latent infection as sexually differentiated adult worms are able to reproduce (5). At that point new microfilariae are shed into the blood and new mosquitos can be infected. Depending on worm load dirofilaria immitis parasites occupy pulmonary arteries, lungs, and with very large worms loads even the right atrium and ventricle of the dog’s heart (5). Figure 2: The life cycle of dirofilaria immitis (5) Symptoms and Diagnosis During the early stage of dirofilaria

Get Access