Hiv-1 Essay

Antivirals are the treatment for HIV and presently there is no known cure. Treatment most often involves combinations of different drugs to avoid creating strains of the virus that are immune to single drug treatments (Mayo Clinic, 2013). The number of CD4 or T cells monitors treatment response. The viral load should be undetectable while undergoing antiviral therapy. The count is checked when treatment starts and usually monitored every 3-6 months. Even if someone has an undetectable viral load, the spreading of HIV is still a possibility.

The term Human Immunodeficiency Virus is commonly known as (HIV), which is a virus that attacks the immune system of humans by destroying the amount of CD4 cells in their bodies. Without CD4 the human body is unable to fight against diseases, which can lead to Acquired Immune deficiency syndrome known as AIDS for short. The first case of the HIV/AIDS virus in the U.S. occurred in the early 1980’s. The first spark of the virus was found in San Francisco with couple of homosexual Caucasian American males. Today African Americans account for the largest proportion of HIV and AIDS in this country, represent approximately 13% of the U.S. population, but accounted for an estimated 44% of new HIV infections in 2010(the last year a study was

Human Immunodeficiency Virus is HIV that develops into AIDS, which is Acquired immunodeficiency syndrome. This virus starts to break down white blood cells, as a result the immune system starts to deteriorate and our greatest shield cannot fight any longer (Mayo Clinic, 2016). The CDC (2015) states, that over 1.2 million people live with HIV in the United States and most who are infected are oblivious of their disease. Healthy people 2020 has declared HIV a public health crisis in the United States, and continues to sweep the nation with more than 500,000 new cases each year (HealthyPeople2020,2016).

CD4 is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. HIV infects cells of the immune system called T lymphocytes (T cells) and macrophages. HIV has an envelope and contains two copies of single-stranded RNA as the genome. Within the viral capsid are important viral enzymes called reverse transcriptase, integrase, and protease. The HIV virus has a spike protein that is called gp120, and the host cell receptor is CD4+. HIV belongs to a class of viruses called retroviruses. Retroviruses are RNA viruses, and to replicate or reproduce, they must make a DNA copy of their RNA through transcription and translation. It is the DNA genes that allow the

Recent studies suggested that CD4 domain specific monoclonal antibody such as mAb (15A7) and Ibalizumab have a great revolution in HIV-1 treatment area. The majority of previous mentioned treatments constitute to either restore the immune response or decline the plasma vireamia, however, this type of treatment is more likely to interfere with the HIV-1 structure. Before explaining how this category of drugs works, it is necessary to clarify the reaction between HIV-1 glycoproteins and CD4. Once the virus enters the body, HIV-1 envelope glycoprotein (gp120) attaches to a cellular CD4 receptor. As CD4/gp120 is formed, it allows gp120 to attache to chemokine receptor-5 (CCR5) or CX chemokine receptor-4 (CXCR4) allowing gp41, another viral envelope molecule, to insert into the target cell membrane leading to fusion the viral envelope and cellular membrane (Christopher et al., 2010). Ibalizumab is CD4 domain-2 monoclonal antibody using as an effective treatment to enhance the CD4 counts. In a study which set out to determine the antiviral efficacy of Ibalizumab on HIV-1 positive patients not on (ART), (Christopher et al., 2010) found that the CD4 counts increase after one day of drug initiation even before the viral load decline. This suggested that the rise of CD4 counts is possibly due to redistribution of CD4 cells from lymphoid tissues rather than regeneration of these cells. Notably, niegher

recognize a protein that is present on the surface of all HIV strains and neutralize the effects of the

HIV is a sexually transmitted disease that attacks the body’s immune system by diminishing CD4 cells that help prevent and fight illnesses. HIV is a virus, more specifically a retrovirus that transcribes its RNA into the host cell’s DNA, and is spread by a transfer in bodily fluids namely drug injection and condomless sex. As the disease progresses into acquired immune deficiency syndrome (AIDS), the virus continues eliminating CD4 cells until the immune system becomes virtually ineffective [5]. Scientists first identified HIV in 1985 in response to the AIDS crisis plaguing the United States [6]. With no cure yet available, those affected with HIV must rely on antiretroviral drug therapy to decrease their chances of developing AIDS [7].

HIV stands for human immunodeficiency virus and can lead to acquired immunodeficiency syndrome (AIDS) if not treated (About HIV/AIDS, n.d). Unlike some other viruses, the human body cannot fully rid itself of HIV completely, even with treatment. Simply put, once you contract HIV, you have it for life. This disease attacks the body’s immune system, specifically the CD4 cells (T cells), which help the immune system stave off infections. When left to its own devices, HIV reduces the number of CD4 cells (T cells) in the body, making the person more likely to

What is HIV? It is a virus that attacks the body’s immune system that can lead to acquired immunodeficiency syndrome or AIDS if not treated. The Kaiser Family Foundation (2008), states that HIV attacks the body’s immune system, specifically the CD4 cells (T cells), which help the immune system fight off infections. If left untreated, it reduces the number of T-Cells in the body, making the person more likely to get other infections. Also noted is the fact that HIV destroys so many of these cells that it renders the body helpless in fighting off the infections, while it takes advantage of the weaker immune system. This occurrence is part of the

Description: HIV, also known as human immunodeficiency virus, attacks the immune system allowing the patient's body to not be able to protect itself. “HIV attacks and destroys the infection-fighting CD4 cells of the immune system. The loss of CD4 cells makes it difficult for the body to fight infections and certain cancers. Without treatment, HIV can gradually destroy the immune system and advance to AIDS” (National Health Institute). The disease was believed to originated in the Congo during the 1900’s, but now is present

“HIV stands for human immunodeficiency virus. If left untreated, HIV can lead to the disease AIDS (acquired immunodeficiency syndrome). HIV attacks the body’s immune system, specifically the CD4 cells (T cells), which help the immune system fight off infections” (AIDS.Gov, 2016).

Human Immunodeficiency Virus, also known as H.I.V is a virus with a self-explanatory name, if we understand the meaning behind each word. Humans are the only ones affected with this particular virus. When a person becomes infected their immune system becomes impaired due to the fact that the virus destroys the T cells. These T cells help the body to fight disease. The only way for the virus to replicate is through taking control of the cells in the body of the host.

during the window period, an interval of three weeks to six months between the time of HIV-1

HIV is the human immunodeficiency virus that causes AIDS. A member of a group of viruses called retroviruses, HIV infects human cells and uses the energy and nutrients provided by those cells to grow and reproduce. AIDS (acquired immunodeficiency syndrome) is a disease in which the body's immune system breaks down and is unable to fight off certain infections, known as "opportunistic infections," and other illnesses that take advantage of a weakened immune system. When a person is infected with HIV, the virus enters the body and lives and multiplies primarily in the white blood cells. These are the immune cells that normally protect us from disease.

HIV, or the Human Immunodeficiency Virus, is a virus which damages and kills cells of the immune system. It attacks the T-cells, key cells of the immune system, and uses them to make copies of itself. After being infected with the virus it progressively interferes and eventually destroys the immune system's ability to fight the anti-genes. HIV may develop into the syndrome AIDS, the Acquired Immunodeficiency Syndrome. HIV is an STD - a sexually transmitted disease - and therefore most commonly it is spread through sexual contact, and the virus mainly enters the body through the penis, mouth, lining of the vagina or vulva during sexual activity. HIV can also be spread through sharing syringes or needles with someone who is infected with the