Hypothyroidism : Understanding Thyroid Function And Treatment Essay

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Laboratory Report/ Brent Good/ Homeostatic Imbalances of Thyroid Function/ Thomas Redenbaugh/ 12.09.2014/ Page [3] of

Starting during prenatal development and continuing throughout life, thyroid hormones pay an important role in the cardiovascular system, the relationship in which has been seen to change in the case of thyroid dysfunction. The relationship between the heart and the thyroid has been demonstrated through a series of experimental and clinical studies and the results determined that in the case of hypothyroidism parameters such as blood volume and heart rate have been seen to decrease from 100% and 72-84bpm to 84.5 % and 60-80bpm respectively. The regular measurements of both the patients cardiac output and systemic vascular resistance have also been seen to change, shifting from 4.0-6.0 L/min and 1500-1700 dyn·sec/cm-5 to <4.5 L/min and 2100-2700

Central Idea: The thyroid controls so many things in your body and if not well taken care of can cause major damage to a person or their life.

The thyroid stimulating hormone receptors are G-protein linked and are found extracellularly in the thyroid glands. When activated, synthesis of hormonally active iodothyronines T3 (triiodothyronine) and T4 (thyroxine) begins (Park and Chatterjee, 2005). This process begins with iodide is transported into the thyroid gland by the sodium iodide symporter found in the membrane of thyroid follicular cells (Park and Chatterjee, 2005). The iodotyrosine residues monoiodotyrosine and diiodotyrosine are then formed through iodine organification where the iodide is oxidised using hydrogen peroxide and then bound to tyrosine in the thyroglobulin (Park and Chatterjee, 2005). The residues then bind together to form the hormonally active iodothyronines aforementioned (Park and Chatterjee, 2005). Many catalytic enzymes mediate this process and are needed to ensure proper thyroid hormone synthesis. Failure in any steps of the synthesis process leads dyshormonogenesis and could be the result of genetic defects. Adequate synthesis of active thyroid hormone is necessary for the regulation of many developmental processes (Richter, C. et al.,

Hyperthyroid can be treated with a pill called beta blockers. Beta blockers slow down your heart rate to make you feel better, though this does help it does not work forever and it is not as safe as medication to treat hyperthyroidism. Radioactive Iodine is also another pill taken orally and will ablate the thyroid making you hypo as will a thyroidectomy( a thyroidectomy is the surgical removal of the thyroid gland ). In either of the two potions you will become hypo requiring you to take daily medication to replace

The thyroid may be very small and seem insignificant in the grand scheme of things, but it plays a very important role in the function of the body. The thyroid gland takes iodine (which is found in many foods) and it converts it into thyroid hormones. These hormones are thyroxine (t4) and triiodothyronine (T3). Thyroid cells are the only cells in the body which can absorb iodine. Hyperthyroidism and hypothyroidism are two conditions that stem from the thyroid malfunctioning. This paper will go into the about the two conditions, the similarities, and the differences.

The aim of the hypothyroid treatment is to reverse clinical progression and correct metabolic derangements which can easily attained in the majority of the patients by the daily oral administration of the synthetic thyroxine (T4). The thyroid

A link to hear the pronunciation of hypothyroidism is: https://www.merriam-webster.com/dictionary/hypothyroidism. You can click on the red speaker button to the right of the word to hear the pronunciation.

If Hypothyroidism is not treated mental retardation occurs. Treatments should be given to hypothyroidism to prevent from anemia, low body temperature and heart failure. Hypothyroidism is treated by replacing the thyroid gland to function properly by releasing thyroid hormones. The hormonal replacement therapy is life long medication. Regular monitoring of the hormone level with physicans diagnosis is required to improve the condition. (Medscape, 2017)

2. In 1891 a man by the name of Murray treated a myxedematous patient with sheep thyroid extract and notices clinical improvements. In 1927, the hormone was synthesized by George Barger and Charles Harington. Synthetic thyroxine became available in the 1950’s although not under FDA approval. However, it wasn’t until the 1960’s that the usage of Levothyroxine became the standard in the treatment of hypothyroidism. In 2007 the FDA announced that

Hypothyroid is evaluated and is diagnosed by a physician; usually an endocrinologist or your primary care doctor. Symptoms, signs and several factors are taken in to consideration when the hypothyroidism is being diagnosed – all of which help identify the cause and severity of the disease. Symptoms alone cannot determine if a patient has hypothyroidism. Many of the symptoms of hypothyroidism are common complaints found in patient with a normally functioning thyroid gland. So, it is hard to decipher if the symptoms relate to the patient’s thyroid. After thorough review of the patient’s symptoms, medical and family history, risk factors, physical examination, and most effectively, a blood test, a diagnosis is reached. There are several types

Hypothyroidism and hyperthyroidism Although correspond to diseases of the thyroid glands, it is very different versions. The thyroid gland is located at the front of the neck and is the one that regulates almost all metabolic processes of the organism, that is when the production of this hormone affects the entire body ends having symptoms and conditions requiring

Misdiagnosis is the number one reason doctors overlook Hasimoto’s Disease. It has proven itself costly over the years. Many patients have suffered their entire lives receiving treatment for the wrong disease. “The vast majority of hypothyroid cases are being treated inappropriately

It is a known fact that it is a lot easier to prevent a disease than to treat it. It is the same when it comes to thyroid dysfunction. You must be very careful if you notice any changes in your body, in order to go and see a doctor as soon as possible. In order to be well-informed regarding this aspect, you must take a look at the following early signs of thyroid dysfunction.