Malignant Neoplastic Disease

Solid tumors can be either malignant or benign. Malignant solid tumors are cancerous, while benign solid tumors are not. The names of solid tumors vary depending on the cells or tissues that from them. Examples of solid tumors include sarcomas (connective tissues e.g. fat cells, muscles, nerves, tendons etc), carcinomas (begin in tissues that lines the internal surface of the body and body organs e.g. breast, lung, prostrate, and colon), Lymphomas (affects the immune system).

Over the past decade breast cancer has become one of the most predominant diseases in the United States. Breast cancer starts out as a malignant tumor in the tissues of the breast which is formed from the uncontrolled growth of abnormal breast cells. Breast cancer is the most common cancer in women, but it can also appear in men. (Stephan, 2010)

This type of breast cancer begins in the milk ducts of the breast. At first, there are normal cells, but then a mutation occurs. Some kind of carcinogen damages and changes a couple of genes. The mutated genes associated with breast cancer are Genes BrCA1 and BrCA2. The

Malignant Melanoma is also called Melanoma or Cutaneous Melanoma. Melanoma is a type of cancer that usually starts with on type of skin cell. The main three skin cells are squamous cells, basal cells and melanocytes. Melanoma starts in the melanocytes. The tumors of melanoma is usually black or brown due to the cells still make melanin. Sometimes it does not make melanin so it will be white, pink, or tan. This cancer can develop on any part of the skin, it is commonly on the chest and back for males and legs for women. The neck and face are other common areas. Having very dark skin can help lessen the risk of getting melanoma in these common areas, but anyone can get it in their nails, bottoms of their feet ,and the palms of their hands. These

A female breast consists of fatty and fibrous connective tissues. The interior of the breast is divided into about twenty different sections called lobes. Each of the lobes is further divided in to lobules, which are structures that contain small milk-producing glands. These glands place the milk into tiny ducts. These ducts take the milk through out the breast and store in a chamber located below the nipple.

Being ambushed by an abrasion on our skin whether it be a pimple, a scar, or something with greater depth such as malignant melanoma can cause quite the adrenaline rush. Diseases of the integumentary system are just as life threating but can be even more mind boggling than a disease occurring internally. For a person to actually see the change in their skin while taking steps to cure it on their own with home remedies and skin care treatments just to find out that the disease is beyond just a simple “break-out” or rash can cause other problems such as stress and insecurity. The integumentary system fights as a barrier to protect the skin and also excrete waste, diseases sometimes hinder this system from doing its main job; which is defending

Cancer occurs when cells in the human body create irregularities and start to duplicate at anomalous quick rates. The outcome is the development of tumors in or on the surface of the body and organs. Tumors might be generous (not destructive) or threatening (harmful). Since ordinary cell improvement and duplication is a moderate procedure which is well controlled, it is evident when cells duplicate so rapidly.

Propelled malignancy is growth that has spread to far off parts of your body. This can incorporate your liver, brain or bones. Treatment relies on upon your general wellbeing and how best in class the growth is. It might be conceivable to hold the tumor under control by surgery or chemotherapy. Radiotherapy and chemotherapy can both help control side effects by contracting a disease with the goal that it doesn't bring about weight and torment and moderates its development. This is called palliative treatment.

Another cause of osteomalacia, although very uncommon, is tumor induced, also know as oncogenic osteomalacia (Kaul et al., 2007). The most common tumor form is phosphaturic mesenchymal and this tumor releases excess fibroblast growth factor-23 (FGF23). The release of FGF23 results in hypophosphatemia, or low phosphate levels in the body by decreasing small intestine and renal resorption of phosphate (William et al., 2011). FGF23 also inhibits 1α-hydroxylase which prevents the formation of the active form of vitamin D. In normal conditions, the bones increase the release of FGF23 when phosphate levels are high, so one can imagine how severe osteomalacia can result from the body being told it has too much phosphate when

Breast cancer is a malignant tumor in the glandular tissues of the breast. Such tumors, also called carcinomas, form when the chemical processes that control normal cell growth break down, enabling a single abnormal cell to multiply at a rapid rate (Hickman). Carcinomas,

“Cancer” is the name for a group of diseases that start in the body at the cellular level. Even though there are many different kinds of cancer, they all begin with abnormal cell growth with the potential to invade or spread to other parts of the body. These abnormal cells lump together to form a mass of tissue or “malignant tumor”. Malignant means that it can spread to other parts of the body or Metastasize . If the breast is the original location of the cancer growth or malignant tumor, the tumor is called breast cancer. (American Cancer Society, 2014, as cited in cbcf.org)

Breast Cancer is made up of glands also known as lubes. In a women breast the small tubes (lobules) carry milk to the nipples (ducts) . Breast cancer begins in the cells that are in the in the ducts. It can also start in other cells of the breast tissues. There is a pathway in the breast called lymph. Lymph causes the cancer to spread throughout the breast. The vessels that carry clear fluid instead of blood connect lymph.

Patients with primary immunodeficiency (PID) are at an increased risk of malignancy compared with the normal population [1-4]. After infections, malignancy is the second most common cause of death in these patients [1]. According to the Immunodeficiency Cancer Registry (ICR) database on immunodeficiency-associated cancer at the University of Minnesota, the most common types of malignancies among PID patients are NHL, which account for 48.6 percent of cancers seen in PID patients. (UPTODATE). NHL is frequently caused by infection with the ubiquitous EBV. The infection of B-cells by EBV provokes a marked activation of immunoregulatory T-cells and requires restoration of immune homeostasis during convalescence. This is accomplished with difficulty in an individual with significant immune defects. (PAAM). It is not surprising, therefore, that immunodeficient individuals are at great risk of developing immunoregulatory disturbances and lymphoproliferative diseases when confronted by EBV. Patients,

Soft tissue sarcomas are a rare form of tumour, accounting for less than 1% of all cancer and arise from mesenchyme. Low-grade fibromyxoid sarcoma (LGFMS) is a form of fibrosarcoma which has a high tendency to metastasise1. It commonly occurs in the deep soft tissues in the lower limbs but can also be found in the trunk, groin and upper limbs. Its peak incidence is in 20-50 year olds with no gender predilection and it commonly presents as a firm, painless, slow-growing tumour 1 2. Evan’s first described this tumour as ‘bland-appearing fibroblastic spindle cells in a predominantly fibrous but partly myxoid matrix’ 3.

The lymphatic system helps to protect us from infection and disease. It’s part of the body’s immune system. Lymph fluid passes through lymph nodes which are connected by a network of lymph vessels. The nodes are found throughout the whole body. My understanding of the lymphatic system is that it is a one-way drainage process that transports fluid from your body’s tissues into the blood circulation, it fights infections and gets rid of waste products produced by your cells. Lymph fluid normally flows through the network of lymph vessels that connect to a group of lymph nodes. The nodes, which are about the size of a baked bean and are located in specific parts of your body act as a filter, destroying or trapping anything harmful that the body