Methicillin Research Paper

Methicillin-resistant Staphylococcus aureus, or more commonly, MRSA, is an emerging infectious disease affecting many people worldwide. MRSA, in particular, is a very interesting disease because although many people can be carriers of it, it generally only affects those with a depressed immune system; this is why it is so prevalent in places like nursing homes and hospitals. It can be spread though surgeries, artificial joints, tubing, and skin-to-skin contact. Although there is not one specific treatment of this disease, there are ways to test what antibiotics work best and sometimes antibiotics aren’t even necessary.

Describe methicillin resistant Staphylococcus aureus (MRSA) and its implications for patients who are diagnosed with this.

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Staphylococcus aureus (S. aureus) is a spherical bacteria which is known to produce a cytotoxin called Panton-Valentine leucocidin (PLV) which destroys leukocytes, and kills tissue (Lina et al., 1999). Five percent of strains of Staphylococcus are known to produce the disease-causing toxin (Lina et al., 1999), but though the amount of PLV-producing strains is somewhat small, the strains which produce PLV are apparently resistant to vancomycin, an antibiotic commonly used to treat staph infections (CDC, 2002). The first recorded case of S. aureus resistance to vancomycin was a reduction in sensitivity to the antibiotic observed in Japan, and has since spread to the United States (CDC, 2002). The most common source of infection of these drug-resistant bacteria are actually in hospitals, wherein the patients are exposed to the bacteria and subsequently infected (CDC, 2002).

In today’s society it has become apparent that “antibiotic-resistant superbugs are the world’s greatest threat to humans now, and into the future. (UQ contact, 2015). In recent years’ bacteria and superbugs have adapted to resist multiple antibiotics including the last line drugs, causing large concern among the medical industry. Staphylococcus aureus, otherwise known as golden staph is a fine example of an antibiotic resistant superbug. Golden staph is becoming more excessively resistant to the most powerful of antibiotics, due to the excessive use of antibiotics the bacteria has mutated drug resistant strains, causing havoc among Australian hospitals.

MRSA (Methicillin Resistant Staphylococcus Aureus) is one of the most recent superbugs to become a health problem. MRSA is a species of Staphylococcus Aureus that is resistant to the antibiotic methicillin and antibiotics like it. Doctors are struggling to find proper treatment because of its resistance to the beta-lactam ring, the core of most antibiotics. The most lethal strain is the CC398 strain, most commonly found on livestock. There are approximately 80,000 invasive MRSA infections and 11,000 deaths every year. (CNN.com)

Methicillin-resistant Staphylococcus aureus (MRSA) is a drug resistant pathogen abundant in healthcare settings and the second most common overall cause of healthcare associated infections (HAIs) reported to the National Healthcare Safety Network (NHSN) (Jernigan & Kallan, 2010). The prevalence of MRSA is a significant problem found amongst many Intensive Care Units (ICUs) in the United States (US); critically ill patients are at higher risk for hospital-acquired infections. Acquisition and infection of MRSA may significantly prolong duration of hospital stays, increase healthcare costs, and contribute to higher mortality rates. According to national data, MRSA accounts for nearly 70 percent of Staphylococcus aureus strains isolated from

Staphylococcus aureus, a microorganism, is the leading cause of today’s infection in the hospital setting in the US. The optimal growth conditions consist of moist, warm, dark environments. On humans, it is usually found in the nares, groin, and axilla. In 1941, the antibiotic penicillin was discovered and was used to treat S. aureus infections. This

Methicillin-resistant staphylococcus also referred to as MRSA is a type bacterium that becomes immune to many antibiotics used to treat even the most common infection. MRSA has become an issue in hospitals around the globe as it is known to constanly change over time. Methicillin-resistant staphylococcus (MRSA) usually occurs in day care home, hospitals and other related health care facilities. It was reported that in 2005 the majority of all infection related cases came from an antibiotic-resistant bacterium, resulting in a high rate of death (Tacconelli, et al 2007). In 1961 (Enright, et al 2002) methicillin-resistant staphylococcus (MRSA) was first discovered in the United Kingdom and later made its way to Asia and after to the United States.

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When penicillin was released to the public in 1944, it was a miracle drug. Infections that had been killers were suddenly treatable. Doctors recommended it generously, both for illnesses that needed it and illnesses that didn’t. Before long, however, it took much stronger doses to see penicillin’s effects. When the antibiotic arms race began in 1944, most physicians assumed that new antibiotics would be discovered or created to keep up with the evolving resistance in bacteria, but the bacteria are constantly evolving new defenses and doctors are starting to run low on antibiotic ammunition. MRSA, methicillin-resistant Staphylococcus aureus, is one of many types of bacteria

Methicillin-resistant Staphylococcus aureus, or MRSA is a source of major concern for public health. MRSA is no longer a sole property of inpatients’ infections, but spreads quickly in the community, responsible for more deaths in the US than AIDS. It demonstrates increasing prevalence not only among people with weak immune systems, but also among those who we consider to be the healthiest.

Methicillin-resistant Staphylococcus aureus, also known as MRSA, is a “bacteria that are resistant to many antibiotics. Staph and MRSA can

Methicillin resistant Staphylococcus aureus (MRSA) has been a type of multidrug resistant organism and staph bacteria known to cause serious infection that can lead to long hospitalizations and death. It can begin as a simple infection on skin or in the lungs, and if left untreated, can lead to traveling to the bloodstream and causing sepsis (“Methicillin-resistant Staphylococcus aureus (MRSA), 2015”). The Centers for Disease Control and Prevention reports that 33 percent of individuals carry the staph bacteria intranasally and two percent of individuals carry MRSA (“Methicillin-resistant Staphylococcus aureus (MRSA), 2015”). Even though this is a serious issue among healthcare settings all over the country, the number of people affected

Take for example MRSA (Methicillin-resistant Staphylococcus aureus), a S. aureus strain that was discovered in 1961 to be resistant to the antibiotic methicillin. Webmd indicates that MRSA has now grown its resistance from methicillin to “amoxicillin, penicillin, oxacillin and many other common antibiotics” (MRSA). This increase in resistance of a methicillin-resistant strain of S. aureus can be attributed to the increasing use and overuse of antibiotics, not only in the doctor’s office but also in agriculture. MRSA is only one of many antibiotic resistant strains of bacteria. New resistant strains are evolving rapidly. According to Dr. Ed Warren, “there are high levels of antibiotic resistance in bacteria causing common infections (e.g. urinary tract infections, pneumonia, bloodstream infections) in all regions of the world” (21).