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Superbug: The Fatal Menace Of MRSA Summary

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A Review of Maryn McKenna’s Superbug: The Fatal Menace of MRSA When penicillin was released to the public in 1944, it was a miracle drug. Infections that had been killers were suddenly treatable. Doctors recommended it generously, both for illnesses that needed it and illnesses that didn’t. Before long, however, it took much stronger doses to see penicillin’s effects. When the antibiotic arms race began in 1944, most physicians assumed that new antibiotics would be discovered or created to keep up with the evolving resistance in bacteria, but the bacteria are constantly evolving new defenses and doctors are starting to run low on antibiotic ammunition. MRSA, methicillin-resistant Staphylococcus aureus, is one of many types of bacteria …show more content…

She begins with the discovery of the strain S. aureus phage type 80/81, a precursor to MRSA, in 1953, less than a decade after penicillin was released to the public. From there, she describes the emergence of MRSA strains first in hospitals and later in the general population. McKenna continues with the emergence and rise to dominance of the virulent and potentially deadly strain of USA 300. She includes the spread of MRSA to pets, pigs, and even an elephant. She additionally addresses the problems faced by schools and prisons in limiting MRSA’s spread. The history of MRSA includes over sixty years of outbreaks, discoveries, and setbacks. Superbug explicates this long and convoluted history so that it is both understandable and interesting to students interested in …show more content…

The main hospital strains are already partially or fully resistant to the effects of commonly used antibiotics. Resistance is also emerging to last resort drugs like vancomycin. The more virulent community strains of MRSA are infiltrating hospitals while the more resistant hospital strain is leaking into the community. The history of MRSA as described in Superbug shows how quickly bacteria can evolve when we add a strong selective force like antibiotics. Around the world, species of bacteria are becoming “superbugs” that are resistant to conventional treatments. Pharmaceutical companies are cutting research on new antibiotics in favor of more profitable investments. We are quickly running out of options for treating multi-drug resistant bacteria. As we move toward a “post-antibiotic” world, there are valuable lessons to be found in the history of MRSA, one of the first superbugs. Students in Emerging Diseases should read Superbug to learn about the complex emergence of

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