Persuasive Essay Sample Research Paper

Over 7,500 animals are killed in zoos because they are deemed surplus, as stated by Liz Tyson an animals rights activist. This giraffe in particular sparked a huge controversy. HIs name was Marius, he was homed at the Copenhagen Zoo and was 2 years old when the staff killed him with a bolt gun. Marius was then dissected and fed to lions in front of ongoing zoo goers. What got people fuming is that he was a healthy, young giraffe. Therefore I believe the killing of Marius should not be justified.

Like most diseases there are treatments and drugs used to treat the cancer. These treatments include chemotherapy, radiation, surgery, medicinal therapy used to target specific cells, and biological therapy used to help strengthen the immune system. Medicine that is used during the stages of melanoma are “Vemurafenib (Zelboraf), dabrafenib (Tafinlar) and trametinib (Mekinist) are targeted therapy drugs used to treat advanced melanoma.” (Mayo Clinic Staff 2016). More test such as biopsies are taken after targeted therapy to analyze how well the drugs are helping diminish the cancerous

can be used in two ways to treat cancer. The first has only been in

While researching in depth Ocular Melanoma, there has been a consistent theme persisting there is not enough research done to find a way to decrease metastasis percentage and increase survival rate. The current attempts at decreasing metastasis and increasing survival rate have stayed the same throughout the course of 4 decades. The current drug, LS2616, is being used to treat Ocular Melanoma patients, but it is used to late to feel the full impact of the drug. Research and Development laboratories are working on a faster-acting drug, but nothing has been tested on mice or released to the public. If new drugs could be created, the survival rate of Ocular Melanoma would increase drastically.

By maintaining Mr. Ryan in the control group and withholding PLX4032, we realize that this decision would only cause Mr. Ryan to suffer, and to die prematurely. Despite dacarbazine being one of the few FDA approved chemotherapy drugs, and thereby labeled the standard form of care in the treatment of metastatic melanoma for over 3 decades, we see that historically this intervention has proven to be ineffective (Bhatia, Tykodi, & Thompson, 2009). Through a pooled analysis, research indicates that this drug has only a 15.3% objective response rate, with only 2% of patients living past 6 years (Bhatia et. al., 2009). Likewise, the side effects implicated with toxic treatment are inevitable with dacarbazine, so subjecting Mr. Ryan to this regimen of treatment causes needless suffering. Even doctors involved in the study, including Dr. Keith Flaherty of Massachusetts General Hospital, have expressed their hatred toward dacarbazine by stating that they would prefer to never give a dose again in their life, and by lobbying for chemotherapy patients worsening in the trial to be positioned in a new trial headed by PLX4032’s competitor

Treatment with this drug has been shown to work already, and approval has been given for its use in combination with another drug, Ipilimumab (Yervoy), which has a similar effect to Opdivo, but by blocking another receptor called CTLA-4. Usually acting as an off switch, by hiding the protein, it further boosts the immune response, comparable to removing the brakes from the immune system. A randomised control trial involving 945 people with advanced skin melanoma was conducted by researchers from a number of international centres (such as The Royal Marsden Hospital and South West Wales Cancer Institution in Swansea) , investigated the potential for this drug combination. Each patient had late stage cancer that was inappropriate for surgical removal, and they all were placed randomly into one of three groups: one for each drug Ipilimumab and Nivolumab alone, and another for a combination. Treatment took place for a year, and assessed the ‘progression-free survival’ of each patient, meaning it looked at how long a patient lives without the disease causing further degeneration, or death. It was found that the average progression-free survival was noticeably greater for people taking both drugs, than either alone: 11.5 months compared to 2.9 months for Ipilimumab and 6.9 months for Nivolumab

Cutting the blood flow off as early as possible provides the best method for controlling growth and eliminating the tumor. As one of the leading causes of death worldwide, NSCLC has very few methods to treat the illness (Koepany, Smyth, and

According to our results a single one-day session SRS with 35.0 Gy is sufficient to treat small and medium stage melanoma (Furdova et al.

et al., 2002). This excited oxygen is very reactive and begins to disrupt cell membranes, especially those of the organelles such as the mitochondria (Barr, H. et al., 2002). A critical threshold of the excited oxygen must be reached to destroy the cells (Barr, H. et al., 2002). In areas surrounding the tumour, the critical state is not reached because the light is targeted onto the tumour, and photodegredation occurs, destroying the photosensitiser (Barr, H. et al., 2002). Photodynamic therapy is most easily applied to cancers of the skin and the throat, such as basal cell carcinoma (Brown & Ibbotson, 2009, p. 252). Photodynamic therapy is also being used to treat precancerous conditions, such as carcinoma in situ and actinic keratosis (Brown & Ibbotson, 2009, p. 252). Photodynamic therapy is also often used in palliatively advanced diseases, for example, photodynamic therapy is used on advanced cases of esophageal cancers, where patients have lost the ability to eat as a result of their disease (Koprowski, 1995). In this case, a fibre optic cable is placed in the patient’s throat, allowing the light of a laser to reach the tumour (Koprowski,

When designing an anti-cancer drug, the results that were found in this experiment need to be considered. It was found that the cells were more likely to uptake the drugs at a higher temperature. In particular the uptake of LDL and transferrin was the most successful at 37°C. This temperature is noted as the body temperature. These results make sense because tumors grow in the human body, so the anti cancer drugs need to be the most effective at this body temperature.

The issue that has arisen is that the results in leukemias are especially promising, with up to a 90% response rate. Lymphomas have also responded well, with up to 40% or 50% of patients responding to treatment. This has resulted in high demand, but a limited number of patients that can currently be treated because of the tedious and

“Your assignment is to write a persuasive essay and present it to the class in a week. You will be graded based on how convincing it is. Today we will be choosing topics,” announced Mr. Bowerbank, my 7th grade English teacher and ruler of classroom 110. My class simultaneously groaned at the prospect of work. I simply lifted my head with intrigue as it was already May and about time we had our first essay. He then proceeded to give examples of topics we could choose and gave us some time to think before we had to tell him our topic. My classmates were already rushing to tell the teacher their idea lest someone else steal it. That meant the usual abortion, death penalty, or drug use topics were out. I really couldn't think of anything and the teacher was slowly making his way through the remaining students like an executioner beheading criminals in a line. I have always thought that he would make a marvelous supervillain if he had a curly mustache, a tophat, and a cape. Eventually my name was called. I slowly dragged myself over to his desk. Even sitting down, he still seemed to tower over me. “What is your topic Cindy?” As usual in such desperate times, my mind turned to food. “Waffles are better than pancakes.” I figured that a waffle was just a differently shaped pancake with a nicer texture. “Hmm. Excellent topic. I look forward to your essay!” I survived to live yet another day.

To gain a better understanding and overall appreciation for the creation and implementation of targeted therapies, it is important to look at previous standards of care for the treatment of cancers and tumors. Conventional chemotherapy, when directed in the direction of specific cells in the body, does not do a very good job at being able to discriminate between normal, healthy dividing cells and tumorigenic cells. This can lead to many different toxic side effects ranging from fatigue and anemia to excessive vomiting, hair loss and in some

Why spend money that is really needed for other things? Why live uncomfortably? Why be trapped in this hole called a home that belongs to another person? Why not live free and peacefully? When a person rents he or she usually throws away money that could be used to purchase something that belongs to them. Money is not easy to come by so why pay out hundreds toward something that is not benefit to the person paying it out. There is no good explanation for making a decision like this. The best option in a situation like this is to buy a house. Buying a house is a better option than renting an apartment.

Having escaped rule from a tyrannical British government, the United States was founded on ideals of freedom and equality for all people. These fantasies of universal egalitarianism turned out to be merely that: fantasies. American history is full of stories of the oppressed struggling to get the rights they deserve and of the controversy over these issues that consequently ensues. “The Hypocrisy of American Slavery” by Frederick Douglass and “We Shall Overcome” by Lyndon B. Johnson are two speeches made confronting two of these issues. Douglass’s speech, delivered in 1852, condemns the institution of slavery and maintains that slaves are men and are therefore entitled to freedom. Johnson’s speech, on the other hand, was written in 1965 and discussed the civil rights movement. In it, he implored local governments to allow all American citizens, regardless of race, to vote. Despite the significant gap in time between these two addresses, both speakers use similar persuasive techniques, including ethos, pathos, and parallelism, to convince their audience that change needs to be implemented in America.