Scheduling of Pharmaceutical Industry
Abstract
Scheduling of pharmaceutical industry is more challenging due to greater complexity of processes. An overview on main time framework used in the basic structure of mathematical programming formulations for the production scheduling. The models are based on continuous or discrete time representation. In this paper I study only importance of these time representation and how to use for the scheduling of processes. I also describe the regular and non-regular production scheduling for the multipurpose batch plants.
Keywords: Process scheduling; Multipurpose plants; Discrete time model; Continuous time model; Constraints.
Nomenclature
Indices
i/i^' order j machines k systems t time slots
Sets
I set of order, i ∈ I and
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Therefore it is important to improve production schedules in order to higher utilization of resources, increased flexibility, reduced response time as well as cutting down the cost of production.
Literature Survey
I review mainly two Journal on the topic related to the scheduling of pharmaceutical industry as given by "Discrete and continuous time representations and mathematical models for large production scheduling problems: A case study from pharmaceutical industry".
In this literature, I found that the choice of time representation is an important parameter in the structure and character of a mathematical model for scheduling. There are two types of time representation - Discrete and continuous. I also learned about the Decomposition algorithm which is used when the complexity of the problems are high. I understand and try to formulate the problem given for continuous and discrete time formulation for the comparison of two models, results and
Akveld, M., & Bernhard, R. (2012). Job shop scheduling with unit length tasks. RAIRO -- Theoretical Informatics & Applications, 46(3), 329-342. Retreived from http://search.ebscohost.com.ezproxy.liberty.edu:2048/login.aspx?direct=true&db=iih&AN=85410818&site=ehost-live&scope=site
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In the aggregate planning module we have added a model to create a transportation problem. For assembly line balancing we have added a display that summarizes the results when using each of the methods. For decision tables we have added an output display for various values of alpha when computing the Hurwicz value. Our most exciting new addition is that in decision analysis we now have an easy-to-use graphical user interface to create the decision tree. In addition, we have added a new model for creating decision tables for one period inventory (supply/demand) problems. In forecasting, we have added a model that allows the user to enter the forecasts in order to run an error analysis. In addition, we have added the MAPE as standard output for all models and added forecast control with computation of the tracking signal. In inventory we have added the reorder point models for both normal and discrete demand distributions. In job shop scheduling, for one machine sequencing we have allowed for inclusion of the dates that jobs are received and we have added a display that summarizes the results when using all of the
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