Plasmodium Falciparum

1133 WordsApr 22, 20155 Pages
Plasmodium falciparum is a protozoan parasite. It is unique of the class of Plasmodium that is the foundation and cause malaria in individuals. There are other Plasmodium species that can cause malaria in humans. Nevertheless P. falciparum is the most common, virulent, and deadly. P. falciparum communicable by the female Anopheles mosquito. P. falciparum life cycle is comprised of two hosts. A P. falciparum carrier female Anopheles mosquito injects sporozoites into the human, infecting their liver cells. Once there infection and damage to red blood cells is critical to the parasites survival. Because red blood cells transport oxygen all over the body, their destruction by P. falciparum causes basic functional devastation to the host.…show more content…
falciparum, whereas in most other countries with malaria transmission, other, less virulent plasmodial species predominate. Almost every malarial death is caused by P. falciparum.[ Malaria is caused by an infection with protozoa of the genus Plasmodium. The name malaria, from the Italian mala aria, meaning "bad air", comes from the linkage suggested by Giovanni Maria Lancisi (1717) of malaria with the poisonous vapours of swamps. This species name comes from the Latin falx, meaning "sickle", and parere meaning "to give birth". The organism itself was first seen by Laveran on November 6, 1880 at a military hospital in Constantine, Algeria, when he discovered a microgametocyte exflagellating. Patrick Manson (1894) hypothesised that mosquitoes could transmit malaria. This hypothesis was experimentally confirmed independently by Giovanni Battista Grassi and Ronald Ross in 1898. Grassi (1900) proposed an exerythrocytic stage in the life cycle, later confirmed by Short, Garnham, Covell and Shute (1948), who found Plasmodium vivax in the human liver. Epidemiology of the major disease/organism. Around the world, malaria is the most significant parasitic disease of humans, and claims the lives of more children worldwide than any other infectious disease. Since 1900, the area of the world exposed to malaria has been halved, yet two billion more
Open Document