Plavix (Clopidogrel)
The drug that will be discussed in this paper is Plavix. Plavix saves peoples veins and arteries from clotting, so it saves people’s lives every day. The pharmaceutical Drug Plavix is a blood thinner. Blood thinners are used to prevent heart attacks most commonly. Plavix is a blood thinner, which means it prevents the formation of blood clots in arteries, or veins. They do not get rid of existing clots, but they prevent them from getting any bigger. When blood thinners are taken with a drug called Aspirin, they prevent the platelets, or a type of blood cell, from sticking together and forming clots. Taking Plavix with Aspirin can also relieve chest pain. Although Plavix can help prevent heart attacks and blood clots, there
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The chemical formula is C16H16ClNO2S•H2SO4 and its molecular weight is 419.9. The molar mass for this drug is 321.82 g/mol. Normally, a person should take 300 mg, unless prescribed more or less. Even though Plavix is usually taken in 300 mg. dosages, it is sold to many patients in 75 mg. as well as 300 mg. tablets. The address of the manufacturer of Plavix is Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership Bridgewater, NJ 08807. Plavix’s website is http://www.bms.com/pages/default.aspx. The manufacturers names are Bristol-Myers Squibb and Sanofi Pharmacueticals. If someone is pregnant, there is no known risk if you take this drug. But, if you drink alcohol and take this drug at the same time, there could be fatal consequences. Lastly, even though it is called a blood thinner, it does not actually make your blood thinner. It just prevents clots. In conclusion, Plavix is a drug that is also a blood thinner. It is taken by mouth and it reacts with platelets. By reacting with these platelets, it prevents clots. But, there are some side effects, some of which could be fatal. And lastly, you can buy this drug from Bristol-Myers Squibb and Sanofi Pharmacueticals. That is why Plavix saves people’s lives every
He should have been taking a blood thinner. This will decrease the blood’s ability to clot. This keeps the existing clots from getting
Warfarin requires the blood be checked regularly to monitor how effective the drug is, i.e. is the blood becoming too 'thin', which could cause an internal bleed or if the Warfarin dose is not effective enough leaving the patient at risk of blood clots.
many different medicines are used to treat coronary heart disease. Usually they aim to reduce blood pressure or widen your arteries. For example antiplatelet are a type of medicine that can help reducing the risk of a heart attack by thinning your blood and preventing it from clotting. However there are also side effects after taking the medication like dizziness, diarrioah, nose bleeds and abdominal pain.
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Product liability laws allow drug users to sue the manufacture, not the FDA, for any adverse drug reactions and side effects. While the FDA oversees drug safety, they do not ensure it. To avoid the costs associated with lawsuits and the risk of a bad name, drug companies do their best to fully, sometimes overly test products before release. “When product liability law attempts to ensure safety already assured by the FDA, prices may be inefficiently high due to liability costs that do not deter manufacturers from producing unsafe products” (Philipson & Sun, 2008, p. 86).
Where does medication come from? How does it get distributed? How do people know how to take it properly? That is all a pharmacists job. Well they don’t actually make the medicine, but the medication that has been made is sent out to pharmacies all over the world to get distributed to people like you.
If you have ever had chickenpox, then you have the varicella zoster virus inside your body which may activate at any time to produce shingles. Therefore, you are at risk for developing shingles later in life. While the majority of cases occur in patients 60 and over, it is possible for younger people to develop shingles. Here’s what you need to know:
As a child, Artemis asked her father, Zeus, to grant her six wishes on her third birthday. Zeus, being the father he was, happily agreed. She wished to be allowed to live her life chaste, without the complications of marriage, to have a bow and arrow like her brother, Apollo’s, a hunting costume, the job of bringing light into the world, sixty nymphs to be her companions, and all the mountains on the earth to live on.
Clopidogrel is a second-generation thienopyridine antiplatelet agent used in humans and other species including cats to reduce the risk of thromboembolic diseases secondary to cardiovascular diseases and other systemic diseases. Once it’s converted to clopidogrel active metabolite by Cytochrome P450 isoenzymes, clopidogrel irreversibly inhibits one of the platelet ADP receptors leading to an inhibition of platelet activation and aggregation. Several large clinical trials revealed that clopidogrel administration in human patients significantly reduced the platelet activation and aggregation in vivo, and decreased the frequency of developing thromboembolic events (Sabatine MS et al. JAMA 2005, Yusuf S et al. NEJM 2001, Chen ZM et al. Lancet 2005).
In the late 1950s, the Thalidomide drug was used in Europe to treat morning sickness in pregnant women among other things. This study involved manufacturing company providing samples of this drug to physicians and compensating them to study the benefits and results of this drug. Although allegedly this drug did not cause any harm to the mother the fetus suffered severe damage as a result. There were thousands of children born with
Enoxaparin is a low molecular weight heparin used to prevent thrombosis, particularly post surgery. Enoxaparin binds to antithrombin III which is responsible for inhibiting coagulation by acting on factor Xa. Enoxaparin accelerates the activity of antithrombin III therefore preventing clot formation (McKenna & Lim, 2014 p766). When a blood vessel is damaged, platelets in circulating blood stick to the site of injury and release chemicals that attract more platelets causing aggregation. There are both intrinsic and extrinsic pathways causing thrombi to form to maintain a closed cardiovascular system (Hollar, 2017). Immobility increases risk of thrombus formation as the blood becomes stagnant with gravity and decreased
Tissue plasminogen activator is a fibrinolytic drug which is used to treat thromboembolic disorders, such as ischaemic strokes. These agents initiate secondary fibrinolysis to occur; altering the haemostatic capability. The primary purpose of this agent is to clear occluded blood vessels within the systemic circulation (Bryant & Knights 2011, pp.534-536).
Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke.
NSAIDs can lead to an increased risk of adverse cardiovascular thrombotic events, including MI and stroke. Platelet adhesion and aggregation may be decreased with Naproxen, prolonging bleeding time. Hematologic side effects induced by Naproxen include platelet dysfunction resulting in increased bleeding times, decreased hematocrit, eosinophilia, granulocytopenia, neutropenia, leukopenia, thrombocytopenia, and agranulocytosis. Due to hematologic side effects, a complete blood count and coagulants must be monitored closely (Lexi-Comp,
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