Disease Condition
Rheumatoid arthritis is an autoimmune, systemic disease that occurs in approximately 1% of the population. There are environmental, hormonal, and genetic factors that contribute to rheumatoid arthritis, with genetic factors having an increased effect. Rheumatoid arthritis is three times more prevalent in women than in men, and also tends to progress with age. Pregnant women with rheumatoid arthritis have decreased signs and symptoms, but at postpartum the signs and symptoms will resume with marked increase due to hormonal influence (Nelson, 2011). There are no known exact causes for rheumatoid arthritis, but autoimmunity does play a role in the progression and level of chronicity. Uncontrollable risk factors are related to family history and the state of one’s immune system. Controllable risk factors are considered environmental and include, but not limited to, smoking, alcohol, excessive intake of coffee, low vitamin D levels, oral contraceptives, and low socioeconomic status (Nelson, 2011).
Since rheumatoid arthritis is a systemic disease, it can also affect other organs and tissues, but it primarily attacks the joints in a symmetrical fashion. Rheumatoid arthritis develops from an abnormal immune response caused by exposure to an antigen, in a patient that is genetically susceptible. Autoantibodies develop and attack the patient’s cartilage and synovial tissues once the antigen exposure has occurred (Nelson, 2011). One of the most common
Rheumatoid arthritis is a systemic disease that affects whole systems of body particularly cardiovascular system, nerves, respiratory system (RACGP, 2009). The causes of rheumatoid arthritis are unknown but it is hereditary which assists to have a risk of rheumatoid arthritis by 50%-60% (RACGP, 2009).
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the
Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And
Rheumatoid Arthritis has been subject of numerous studies and researches in the look for a better understanding of how it effects the individuals diagnosed with it. There is a higher incident of females diagnosed with RA than male as well as a relationship with genetic and environmental factors involved. Around one percent of the world population is affected by RA; therefore, diverse studies have been performed to understand how the lives of the diagnosed patients can be impacted by the disease. For example, how RA affects the mobility, safety and activities of daily living in general as well as the development of interventions to better approach RA. On
Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small
Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease. The disease happens when the immune system mistakenly attacks a healthy tissue as if it was a foreign invader, such as a virus or bacteria. If left untreated it can lead to permanent joint damage, decrease in quality of life, and total disability. It affects over a million people in the U.S. alone. Rheumatoid arthritis symptoms include persistent joint inflammation which causes joint pain, stiffness, and swelling. Fatigue and stiffness are usually early symptoms. Joint pain can be an early symptom in a variety of diseases. Symptoms of rheumatoid arthritis often develop slowly over a period of weeks or longer, but this is not always the case, it can have an acute
Many people all over the world may have rheumatoid arthritis. Rheumatoid Arthritis is a chronic inflammatory disorder that affects the small joints in the hands and feet (Mayoclinicorg, 2015). It is also an autoimmune disease, where the immune system sees the body as a foreign object and attacks it (Mayoclinicorg, 2015). As the chronic disorder matures, it could seep into the blood vessels and into other organs: heart, lungs, skin, and eyes (Mayoclinicorg, 2015). This chronic pain is found mostly in women around forty to sixty years old; however, men with low testosterone could also have the chronic disorder (Mayoclinicorg, 2015). Because smokers burn off certain cells to prevent infection, they are also at risk for rheumatoid arthritis. This
Rheumatoid arthritis is a chronic autoimmune disease that is characterized by inflammation and destruction of the joints (1). It usually affects joints asymmetrically, or on both sides of the body
Rheumatoid arthritis is a chronic inflammatory disease affecting the joints, most often in the hands and feet. It results in swelling, stiffness, pain, and sometimes joint, bone, and cartilage destruction. Rheumatoid arthritis usually affects joints on both sides of the body equally, meaning if a joint on one side is affected, the same joint on the opposite side is affected as well. Rheumatoid arthritis belongs to a group of diseases called autoimmune disorders that affects joints. In rheumatoid arthritis, the immune system produces antibodies that attack the soft tissues lining of the joints. Eventually the cartilage, bone, and ligaments of the joint deteriorate, causing deformity, instability, and scarring within the joint
“It occurs worldwide and, until age 65, is three times more common in women than men” (Rosdahl and Kowalski, 2012, p.1235). However, this disease is more common in the middle aged- elder adults. It is considered an autoimmune disease because the body will begin to attack its own body tissues. Rheumatoid arthritis can also cause harm to other body systems (systemic), such as the cardiovascular system resulting in issues of blood vessels, the integumentary system causing issues with the eyes and skin, and of the respiratory system which can cause problems of the lungs (Staff, 2014). Hypothyroidism is a disease that is the most closely associated autoimmune disease to rheumatoid arthritis, and its characteristics are determined by a rheumatologist to rule out and distinguish between the two diseases (Vij and Kumar,
Rheumatoid Arthritis is an inflammatory disease of unknown etiology with an autoimmune pathogenesis; it has the characteristics by arthropathy with severe bone deforming and systemic manifestations (Negrie, et
Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.
Rheumatoid arthritis is a disease that has direct involvement with the immune system. This disease is considered to be degenerative and currently the only thing that can be done is manage the painful symptoms and suppress the self targeting actions by using immune suppressing drugs. The cause of rheumatoid arthritis is mostly unknown but there is a high amount of evidence that there are genetic predispositions for the disease. This being said however there are also environmental factors to asses these include, bacteria, viruses, fungi and other environmental factors. Doctors primarily use a physical examination to first suspect R.A. then send for blood work to confirm. There are many aspects to this disease and many questions left
Rheumatoid arthritis is an autoimmune and systemic disease damaging many joints in all parts of the body. In this state, body’s immune system activates a self-regulated immunological cascade that ultimately leads to joint damage. Rheumatoid arthritis begins in synovial tissues attached to the joints and then extends towards cartilage. It is described by
So far, researchers have found genetic and environmental factors to play the largest role in the causes of Rheumatoid Arthritis. (“Early treatment of rheumatoid arthritis is important,” 2016). Researchers have found that the genetic makeup of a person can help pre-determine if a person will be diagnosed with Rheumatoid Arthritis, and even goes on to pre-determine how intense the disease will affect the individual. Although the environmental factors are still being researched, scientist are beginning to believe that there is an environmental trigger that happens to bring on the onset of Rheumatoid Arthritis in an individual. (Vital, Communications, & Liaison, 2016) It is found that hormones also play a role in the development of Rheumatoid Arthritis. Research followed this theory once Rheumatoid Arthritis began appearing more in women than in