Sickle Cell Anemia Complications

Sickle cell anemia is a hereditary disorder that mostly affects people of African ancestry, but also occurs in other ethnic groups, including people who are of Mediterranean and Middle Eastern descent. More than 70,000 Americans have sickle cell anemia. And about 2 million Americans - and one in 12 African Americans - have sickle cell trait (this means they carry one gene for the disease, but do not have the disease itself).

Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia.

In conclusion, sickle cell anemia and the sickle cell trait are more common in African-Americans and people who live in places where malaria is common. Individuals with the trait seem to live normal and healthy lives, however individuals who have the trait and experience high altitudes or vigorous exercise tend to feel unwell because of the lack of oxygen getting into the cells causing them to sickle. In addition, the sickling of the cells can be reversible to a certain extent in people with the trait, however people who have sickle cell anemia the sickling of the cells is irreversible due to the severity of the disease.

Sickle cell anemia is an anemia that is inherited and mostly affects people whose heritage can be traced back to places where malaria was prevalent. There are approximately 100,000 Americans that have the disease and many more with the trait. Several of my family members are afflicted by this medical condition that causes red blood cells to take on an irregular shape.

Sickle cell disease is an inherited form of anemia. This means both parents must pass on the defective gene for a child to be affected. The gene is more common in families that come from Saudi Arabia, Africa, Mediterranean countries, India, the Caribbean islands, and North, South, and Central America of African descent.

It has always been assumed that genetics and lifestyle play a major role in the presence of health disparities and health care issue that affects African-Americans. This paper provides a historical background to a key disease more prevalent in the African American community, Sickle Cell Anemia, the history behind the disease, genetic mechanisms that influences once probability of inheritance and in-depth treatment on how to manage, prevent and sustain a healthy lifestyle when dealing with sickle cell anemia. Sickle cell anemia is a hereditary disease that alters important aspects of the body physiologically and can be inherited via genes. Sickle cell disease (SCD) was first identified in 1910 and has existed in the continent of Africa for five

The red fluid that circulates in our veins and arteries is none other than blood! Is blood important? But of course it is! Blood’s main function is to act as the body’s transport system and also plays a major role in the body’s defense system against infections (America’s Blood Centers, 2012). Among many things, blood contains red blood cells, the component that carries oxygen to cells, and carbon dioxide away. (ABC, 2012). However, blood disorders pose a threat to the health of the body, sometimes requiring the host to have blood transfusions in order to survive (National Institute of Health, 2012). A particular blood disorder of interest is sickle cell anemia, a condition that affects 300,000 people born every year!

Last semester in clinical, there was a patient with sickle cell anemia and he automatically sparked an interest in me. The patient was quite young and was in so much pain that he could not even bear to be touched by the nurse and reported a pain level of 8. Before my encounter with this patient, I did not know much about sickle cell anemia and decided to do some research on this disease. In my research, I learned that a majority of these patients go through acute pain episodes that occur chronically. After learning this and thinking about the young boy in the hospital, I wanted to discover more about how the pain in these patients are managed and controlled.

Limiting certain substances in the diet can help prevent the buildup of potentially toxic substances that are normally broken down by the enzyme. In some cases, enzyme replacement therapy can help compensate for the enzyme shortage. These treatments are used to manage existing signs and symptoms and may help prevent future complications. For other genetic conditions, treatment and management strategies are designed to improve particular signs and symptoms associated with the disorder. These approaches vary by disorder and are specific to an individual's health needs. For example, a genetic disorder associated with a heart defect might be treated with surgery to repair the defect or with a heart transplant. Conditions that are characterized by defective blood cell formation, such as sickle cell disease can sometimes be treated with a bone marrow transplant. Bone marrow transplantation can allow the formation of normal blood cells and if done early in life, may help prevent episodes of pain and other future complications, according to the United States National Library of Medicine (NIH

Sickle cell anemia is a blood disorder that happen very commonly in the African descent.

Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body. A gene causes the bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia. Older children and adults with sickle cell disease may experience a few complications, or have a pattern of ongoing problems that shorten their lives. The most common and serious complications of sickle cell disease are anemia, pain, fatigue, and organ failure. Today there are many alternatives and opportunities that a sickle cell patient may consider. One outlined in this paper is the Hydroxyurea method.

At first, I would like to say Taina not worry about getting dropped from the team since it should not happen. Even if she is a carrier of sickle cell anemia, the coach would not drop her nor the scholarship. Practice plans for sickle cell anemia carriers would change to less intensive, and the coach could teach them how to control the breath. Sickle Cell anemia is about Oxygen circulation in one’s body, so you should be fine if we can balance it after finding it. Sickle cell anemia is caused by genetic disorders of hemoglobin that is responsible to transport Oxygen to other parts of our body. Red blood cells of patients with this genetic disease become sickle-shaped when the oxygen concentration is low. Lack of O2 results all of the symptoms

Anemia: According to National Heart, Lung and Blood institute, anemia is the most common blood disorder in the United States affecting over 3 million individuals (2015). It develops when the blood lacks oxygen. It is a condition whereby ineffective DNA synthesis occurs as a lack of hemoglobin nutrients. Clinical manifestations develops as a response in the body due to tissue hypoxia and are manifested as dyspnea on exertion, fatigue- as a result of the heavy workload of the organs in the system not functioning properly; dyspepsia with nausea, shortness of breath, dizziness, pale skin, cold hands or feet’s, chest pain and headaches, depending on the severity of the disease and comorbidity. There are different types of anemia: sickle cell anemia,

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. A person that is diagnosed with sickle cell anemia, their blood cells start to become clogged, causing blood clots, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.

Sickle cell disease (SCD) patients undergo episodic or chronic blood transfusions to treat anemia and prevent life-threatening complications. Although blood transfusions provide benefits to SCD patients, there are also associated risks. The risks of transfusion include infectious disease transmission, circulatory overload, acute hemolytic transfusion reactions, iron overload, hyperhemolysis, red blood cell alloimmunization and delayed hemolytic transfusion reactions (DHTR). Alloimmunization and DHTR are one of the biggest challenges and occur in 25-30% of SCD patients. Only those patients who are responders will become alloimmunized. The number of units transfused, the limited or extended phenotypically matched red blood cell transfusion,