African American Parents With The Sickle Cell Trait

1524 WordsOct 31, 20147 Pages
Annotated Bibliography Hypothesis: African-American parents with the Sickle Cell Trait have the greatest risk of passing Sickle Cell Anemia to their offspring. In this article, sickle cell anemia is defined as a hereditary disease that destroys red blood cells by causing them take on an elongated and rigid "sickle" shape. In addition, a different type of hemoglobin called Hemoglobin S, is the protein in red blood cells that carry oxygen throughout the body. This protein starts to wrap around other red blood cells when oxygen is lacking to form a helical shape. Once this happens the cells cluster together and elongate and the cells start to "sickle". A person who has sickle cell anemia can only get it if both of their parents carry the sickle cell trait, if only one parent has the trait then there children are at risk for having the trait. In conclusion, sickle cell anemia and the sickle cell trait are more common in African-Americans and people who live in places where malaria is common. Individuals with the trait seem to live normal and healthy lives, however individuals who have the trait and experience high altitudes or vigorous exercise tend to feel unwell because of the lack of oxygen getting into the cells causing them to sickle. In addition, the sickling of the cells can be reversible to a certain extent in people with the trait, however people who have sickle cell anemia the sickling of the cells is irreversible due to the severity of the disease. In this study,

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