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Sickle Cell Disease : African Americans

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Sickle Cell Disease on African Americans Cristina Martinez Nova Southeastern University Sickle Cell Disease on African Americans Sickle cell anemia is an autosomal recessive hereditary blood disorder which causes damage to the cerebrovascular system including important organs such as the spleen and liver due to abnormal red blood cells (Scott & Scott, 1999). Sickle cell disorder is caused by mutations in the HBB gene then hemoglobin S and other abnormal beta-globin chains create a rigid consistency that is effortlessly lysed and more susceptible of sticking to the endothelial cells of the vascular system (Long, Thomas, Grubs, Gettig, & Krishnamurti, 2011). After deoxygenation causes the sickled hemoglobin to polymerize which leaves the…show more content…
The geographic regions have increased the prevalence of sickle cell among these heritages that are more prone to malaria which has led to this disproportionate impact on African-Americans (Kwiatkowski, 2005). Research shows that mood and stress have shown to be a significant predictor of health care use and work absence (Gil et al., 2004). Positive moods in same-day analyses have predicted fewer hospitalizations, less medication use, ER visits, and calls to health care providers (Gil et al., 2004). Sickle cell disease pain fluctuations have shown to be suggestively associated with daily stress and a negative mood moreover, psychosocial stress, not merely stress secondary to illness, was helpful to predicting pain (Gil et al., 2004). There is no cure for sickle cell disease at the time being but stress can easily increment an individual’s pain levels and decrease their quality of life. Psychosocial issue such as coping with stress, living with a chronic illness, depression, and an overall reduced quality of life (Thompson, Gil, Abrams, & Phillips, 1992). Stress or psychosocial processes and biological processes together have a strong impact on illness – outcome relationship (Thompson, Gil, Abrams, & Phillips, 1992). Negative outcomes can include anything from the type of sickle cell disease, the frequency of painful episodes, and the variation of complications (Thompson, Gil, Abrams, & Phillips,
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