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Statistical Methods Of Data Management And Statistical Analysis By Spss Software Version 13 Essay

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Statistical Methods
Data management and statistical analysis by SPSS software version 13 was used. Baseline laboratory markers were expressed as mean ± standard deviation (SD) or standard of error (SE) when appropriate. Progression free survival and overall survival were analysed by the Kaplan-Meier method. Paired t test was used to compare AFP, size and number of focal lesions after therapy. ANOVA test was used when appropriate, P< 0.05 indicating statistically significance result. Results
The baseline characteristics of 15 patients were shown in table 1. 4 patients had one focal lesion (26.7%), 3 patients had 2 focal lesions (20%), 5 patients had 3 focal lesions (33.3%), 3 patients had four focal lesions (20%). 11 patients had portal vein thrombosis (73.3%). The mean of the sum of tumoral size in its longitudinal diameter is 10.5 ± 4.1 cm, mean Child Turcotte Pugh score was 6.33 ± 0.3, MELD score 13.7±1.4, PS < 2. The patients were given the planned medications and followed up after 1 month with AFP level, abdominal USG and triphasic CT to detect the number and size of lesions. During therapy, 6 patients developed rising bilirubin (40%) to grade 3 which improved after adding ursodeoxycholic acid, worsening thrombocytopenia in 4 patients (26.7%), melena in 2 patients (13.3%) which were improved with temporary cessation of therapy. Hand and foot syndrome in 3 patients (20%).
After one month of therapy as shown in table 2; a highly significant reduction in size of lesions

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