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Summary: Acute Stroke Intervention

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As stated in Acute Stroke Intervention (Prabhakaran, Ruff, & Bernstein, 2015), one of the leading causes of death and disability in the United States are strokes. Acute ischemic stroke (AIS) results when an artery that is supplying the brain becomes blocked, this occurrence leads to cell death of brain tissue. Improving brain function after an ischemic stroke is of high priority for clinical research. General consensus shows that administration of intravenous recombinant tissue plasminogen activator (IV rtPA) therapy is helpful when introduced within 4.5 hours of ischemic stroke symptom onset. The benefit of intravenous (IV rtPA) lessens when the onset of symptoms goes beyond 4.5 hours. The use of (IV rtPA) is contraindicated when there is

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