Systemic Lupus Erythematous Research Paper

     Lupus is a potentially life threatening disease that effects about 1.5 million Americans. Lupus can effect many different parts of the body. Lupus is a type of autoimmune system disorder in which the body cannot distinguish the difference between foreign antibodies and its own organs. So basically what happens is that the body ends up attacking its own organs thinking they are foreign substances. (The Lupus Foundation of America)

Lupus is a lifelong, autoimmune disease. This means that the immune system of a person with lupus cannot tell the difference between its own cells and what is foreign. This leads to the immune system attacking healthy tissue throughout the entire body.

Most know Systemic Lupus Erythematosus (SLE) as simply lupus. It is difficult to diagnose and treat but the symptoms can be mentally and physically devastating for any patient. Many may not realize the extent to which a person with SLE is affected on a day to day basis. It is important for healthcare professionals to understand the disease process, including the cause, signs, symptoms, and treatment of SLE. By understanding the aforementioned, healthcare professionals can assist with reporting signs and symptoms to the patient’s doctor to further reach a correct diagnosis, but to provide holistic care to the patient. SLE is a heterogeneous autoimmune disease which means the body’s immune system fallaciously attacks healthy tissues and various organs, in this case, primarily the skin , joints, kidneys, and brain of both men and women.

Description: Lupus is an autoimmune disease which attacks the healthy body immune system. This immune disorder attacks the brain, kidneys, joints, skin, and other organs in the body.

Lupus is a disease that can damage any part of the body, whether skin, joints, or organs inside the human body. Having lupus means something goes wrong with the immune system, which is the part of the body that fights off viruses, bacteria, and germs. Autoimmune happens and your immune system cannot tell the difference between these foreigners, nor your body’s healthy tissues and creates autoantibodies that attack and destroy healthy tissue. Autoantibodies cause inflammation, pain, and damage in various parts. Lupus is also a disease that my reappear after curing and is not contagious through sexual contact and is not like or related to cancer. Lupus can become life-threatening and should always be treated by a doctor and most people with lupus can lead a full life, “research estimates that at least 1.5 million Americans have lupus.” Anybody can get infected with lupus, any race and ethnic groups

Inflammation of the Kidneys is one of the most serious symptoms of Lupus. When the Kidney are not working properly they leak protein and is eliminated through urination with the lack of protein causes fluid retention and causes swelling or Edema in the lower extremities. This symptom is one of the first signs of lupus nephritis. Lupus affects the kidney functions to remove waste products and excess fluids from the body. A biopsy is used to determine the extent and severity of kidney disease. The tissue gathered is then examined through a microscope to determine inflammation and scarring. Once all the factors are gathered such as amount of protein in the urine, reduction of kidney function, and the Biopsy of the kidney drug therapy may be used to control inflammation and suppress the activity of the immune system. Although high dose of medications may have many side effects when used at high does it is needed to get the inflammation under control and then can be tapered down to a low does with lower side

Lupus is when your tissues and organs are attacked by your immune system without recognizing that they are doing it, and it will continuously do so.Lupus means wolf in latin and it was chosen to because of the red skin inflammation that affects you when you have this chronic disease. It was during the 19th century that this name was chosen. Lupus is a genetic disease, and people who have it genetically may get it activated by the environment. There is no clear cause, but there might be a few things that will give you Lupus symptoms. Being in sunlight may give you skin damage similar to the lupus ones. Sunlight can also give your body an internal response. Infections may start Lupus or bring it back to those who already have it. Anti-seizure medicines may also give you Lupus

Systematic lupus Erythematous (SLE or Lupus) can affect any organ in the body and may cause a wide range of symptoms. SLE symptoms can vary from person to person and can change over time. Lupus affects 1.5 million Americans and millions more worldwide lupus.org (N.d) 2016. The cause of lupus is unknown some research have found genetics and hormones are to play a role. The majorities of people with lupus 90% are female, and they seemed to develop signs and symptoms of the illness between the ages of 15 and 44 (2016). Children are affected with lupus. Approximately 5,000 to 10,000 of the million Americans with lupus are diagnosed while under the age of 18 (2016).African American women are three times more likely than Caucasian women to get lupus

This research paper will explain what lupus is to help others get a better understanding of this diseases. It will cover the history ,and tell us how many people are affected by this silent killer. There are several different types of lupus in this paper we will discuss Systemic Lupus Erythematosus which effect different organs.One will learn which part of the body this disease affects,the signs and symptoms, even the treatment and the side effects.

Elsa lives in the North of England. After she found out she had Lupus for a period of six years, the doctor consultant advised her that her pregnancy was safe. In 2008, following the birth of her daughter, her kidney malfunctioned. She had not known the impact of the disease on her life. She says that the illness made her long hair thick, which gradually fell off her head. This traumatized her also because of the way people treated her when they learnt she was suffering from Lupus. Elsa felt so damaged physically and physiologically, and made her feel uncertain of plans of having more children. Her future seemed unpredictable (Samsom, 2010).

Systemic Lupus Erythematosus, or Erythematous, also known as SLE, is a chronic inflammatory, autoimmune disease that transpires when the body’s own immune system assaults, with “variable manifestations”, it’s own tissues and organ systems throughout the itself1,2,3. This can also include joints, heart, lungs, skin, brain, blood cells, etc1. Systemic Lupus Erythematosus is known to have an impact on the organ network involved with immune complexes and multiple antibodies, especially antinuclear antibodies, or ANAs, an abnormal antibody that is targeted to cause certain edemas throughout the body and different tissues4.

“The most common symptoms of lupus include painful or swollen joints (arthritis), unexplained fever, and extreme fatigue. Because many people with lupus are sensitive to sunlight (called photosensitivity), skin rashes often first develop or worsen after sun exposure”(National Institutes of Health). “Chest pain, hair loss, anemia (a decrease in red blood cells), mouth ulcers, and pale or purple fingers and toes from cold and stress are also other symptoms of SLE.” “New symptoms may continue to appear years after the initial diagnosis, and different symptoms can occur at different times” (National Institutes of

Systemic Lupus Erythematosus is an autoimmune disorder that cause the body to attack its own connective tissue. The diseases effects patients largely in the skin and is thought to be named after the fact that some patients have rashes that resemble a wolf. Lupus also is a disease that is uncommon, appearing in 0.1% of the population and a 9:1 ratio in retrospect of women to men who have the disease. A study of the disease was done by the university of Iowa in 2006 that compared the levels of protein in the blood of patients with Lupus to that of patients who didn’t. To go further, there were 30 participants in the trial and half of those thirty were patients without Lupus.

Systemic Lupus Erythematosus (SLE) is a genetic disorder. SLE is a type III hypersensitivity or an autoimmune hypersensitivity (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). Meaning that the body is attacking itself. In SLE a large number of autoantibodies circulate through the body (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). These autoantibodies are deposited into the connective tissue all over the body (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). These autoantibodies activate the complement system and cause inflammation and necrosis of the tissue that the autoantibodies are near (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). This usually takes place in many systems in the body. In order to be diagnosed at least four body systems have to be affected.

Lupus, also referred to as systemic lupus erythematosus (SLE), is a chronic autoimmune disease that is caused when the body’s immune system attacks its own tissues and organs. Common symptoms include rashes, fevers, skin lesions, organ damage, and stiffness and swelling in muscles and joints. These symptoms cause patients physical pain, which has been shown to increase psychological distress. In other words, lupus patients that experience pain also experience high levels of depression, anxiety, and stress. It was hypothesized that lupus patients may feel a sense of helplessness over their disease in response to the fluctuating degrees of pain. Researchers tested this hypothesis by using Martin Seligman’s learned helplessness model, which states learned helplessness is a feeling of powerlessness as a result of persistent past failure. In this study, the patient’s level of continuous pain would