The Common And Fatal Genetic Disease

Cystic Fibrosis (CF) is an autosomal recessive genetic disease that causes thickened mucus to form in the lungs, pancreas, and other organs. It affects a specific protein called Cystic Fibrosis Transmembrane Regulator (CFTR) that controls the normal movement of sodium, chloride, and water in and out of the cells within the body. Those diagnosed with CF have either too little or abnormal CFTR. When CFTR is absent or defective, the mucus usually secreted by the cells in the pulmonary airways, pancreatic ducts, and gastrointestinal tract become thickened, leading to obstructions, frequent infection, and loss of function in the affected organs (Cystic Fibrosis Symptoms, Causes & Risk Factors, 2018). According to the Cystic Fibrosis Foundation

A widely accepted Caucasian disease has since changed; as cases of its existence are appearing in the South Asian Population (Orenstein, Rosenstein and Stern, 2000). First discovered in 1989, Cystic Fibrosis (CF) is a genetically predetermined condition, its presences is lifelong and highly complex, which is why many CF sufferers and families develop various mechanisms in order to adapt to the condition (Tippingemail, Scholes, Cox, 2010). Cystic Fibrosis causes the body to develop thick, sticky mucus which clogs the lungs and affects other organs in the body, mainly the pancreas. The layer of mucus if untreated develops in to a chronic infection which can be detrimental. The pancreas of a CF patient is most vulnerable, once the mucus has

Cystic Fibrosis, also known as CF, is one of the most common life-threatening genetic disorders found in people. Discovered in 1938 by Dr. Dorothy Hansine Andersen, Cystic Fibrosis severely affects two parts of the human body, including the respiratory system and the digestive system. Cystic Fibrosis causes the mucus glands to secrete very thick and sticky mucus. This mucus then clogs the tiny air passages and traps bacteria in the lungs. The thick mucus also stops the release of digestive enzymes in the pancreas from reaching the small intestine. According to Cystic Fibrosis Queensland (2015) more than one million Australians carry the Cystic Fibrosis Gene, with one in every 25 people, often not realising they are carrying the deadly gene.

Cystic Fibrosis is a genetic disease which is progressive and limits breathing ability. The lungs and other organs are affected by a thick buildup of mucus. This mucus traps bacteria which leads lung damage, infections, and respiratory failure. The digestive enzymes being released is prevented, affecting the breakdown of food and nutrients being absorbed. ?More than 30,000 children and adults in the United States have Cystic Fibrosis. 70,000 people worldwide.? (Diagnosed With Cystic Fibrosis, Cystic Fibrosis Foundation) Someone who has Cystic Fibrosis have a defective gene from each parent which produces faulty protein. The CFTR gene is the gene that is mutated causing this. The channel that transports chloride in and out of cells is created by instructions that are created by CFTR gene. The regulation of chloride ions and water are prevented creating the thick mucus formed on the passageways of lungs, pancreas, and other organs. Cystic Fibrosis doesn?t cause learning problems are mobility of the person. Babies with this still develop and grow up normally. The average life expectancy is close to 40 years, and has been increasing in the last fifty years thanks to improved care. ?Chronic coughing, recurring chest colds, wheezing, shortness of breath, frequent sinus infections, and allergies that last all year, are the most common symptoms of Cystic Fibrosis.? (Cystic Fibrosis Symptoms) Since this disease is progressive

In regards to the digestive tract, organs such as the liver, small and large intestines, gallbladder, mouth, stomach, esophagus, and pancreas are prime locations of complications pertaining to mucus blockage. The pancreas, which is responsible for secreting enzymes assisting in food digestion and insulin for maintaining blood sugar levels, is mainly affected by cystic fibrosis. Thick mucus production creates a blockage within the pancreas ducts and creates a decline in the pancreas’ ability to secrete digestive enzymes to aid in digestion.

Cystic fibrosis is an acquired malady described by the development of thick, sticky bodily fluid. This bodily fluid can make harm a number of the body's organs. The most widely recognized signs and indications incorporate dynamic harm to the respiratory framework and interminable digestive framework issues. The seriousness and elements of Cystic fibrosis fluctuate amongst each influenced person. The bodily fluid that greases up and secures the linings of the aviation routes, digestive framework, the regenerative framework and different organs and tissues is unusually thick and sticky in patients with Cystic fibrosis. This can obstruct the aviation routes prompting serious breathing issues and bacterial diseases in the lungs. The bacterial

Our genetics and DNA design the entire make up of the human body. From our physical appearance to our health and mental capabilities. Parents have dominant and recessive traits that decide the genetic makeup of their offspring. More times than often the match up of the patient’s genes can pass down a genetic disorder to the offspring. One common example of an autosomal recessive disorder is cystic fibrosis. Cystic fibrosis is a genetic condition in which the lungs and digestive system become clogged with thick sticky mucus. When learning about this disorder, it is important to understand the etiology, pathogenesis, and clinical manifestations. Knowing this information will allow for an enhanced perceptive on the people who live with

Cystic Fibrosis (CF) also knows as (mucoviscidosis) is a single-gene disorders. This disorder is best described as an autosomal recessive of the exocrine glands. The disorder itself can be categorized as either pus- forming or hindering airflow. The responsible gene for this pulmonary disorder has been discovered to the be on the long part of the arm of chromosome 7 (Copstead & Banasik, 2013). Major signs and symptoms of CF will be associated with the gastrointestinal and respiratory system. We are able to diagnose CF though laboratory testing such as arterial blood measurements. Treatments for CF tend to be comprehensive including specialty physicians, nutritionists, physical and respiratory therapists and genetic counselors. Medicare

What is Cystic Fibrosis? Cystic Fibrosis is a progressive genetic disease that causes persistent lung infections that limits you the ability to breath. The first ever case of CF was in 1938 by Dr. Dorothy Anderson a Pathologist. He found the disease to be caused by malnutrition Dr. Dorothy called the disease “Cystic Fibrosis of the Pancreas”. Cases of this disease in the 1950s where difficult because people never lived long enough to make it to elementary school. With the advances of technology over the years people with CF live long enough to make a family and finish their careers. Over the years scientist and doctors still have not found a cure for CF. Lung cancer is one of the most serious side effects of getting CF because of mucus getting clogged up in the lungs.

Cystic fibrosis is a genetic disease that affects the respiratory system, digestive/endocrine, and reproductive system. A defective gene produces an abnormally thick mucus in the trachea and causes a blockage in the trachea, damages lung, and resulting in failure of the respiratory system. The mucus also interferes with the pancreas, which it prevents the secretion of digestive enzymes that help dissolve food, causing difficulty in absorbing nutrients. CF causes infertility, particularly in men. However, they are not sterile, therefore they can have children with assisted reproductive techniques. In most cases, many of them are diagnosed with CF before the age of 2 because the newborns are screened immediately after birth. On the other hand,

Cystic fibrosis (CF) is a serious disease that is life-threatening. This disease is characterized by the buildup of thick mucous in the lungs due to a defective gene within the body. It is a disease that is genetic which means that it is passed down from one’s parents. The disease is genetic because patients with Cystic Fibrosis inherit a defective gene on chromosome 7. This gene is responsible for protein production and the moving of water and salt in and out of the body’s cells. If a person inherits on faulty CF gene from each parent the chances are very high that they will develop Cystic Fibrosis. If the person inherits only one faulty gene from their parents and one normal gene they are known as carriers of CF and usually develop no symptoms of the disease and usually end up living normal lives. However they can pass the faulty gene down to their children.

Cystic Fibrosis, otherwise known as CF, is an inherited genetic disease that affects the lungs and digestive system. The disease causes a build-up of thick mucus in the lungs and other organs. Mucus clogs the airways in the lungs and “traps bacteria, leading to infections, extensive lung damage, and eventually, respiratory failure. In the pancreas, the mucus prevents the release of digestive enzymes that allow the body to break down food and absorb vital nutrients.” (#1)

Cystic Fibrosis, or CF, is a genetic disease that affects children to young adults. It occurs when a child has two defective copies of the gene that causes cystic fibrosis, one from each parent. The disease primarily affects the digestive system and it also affects the respiratory system, mainly the lungs bronchi and bronchioles. Cystic fibrosis affects the cells that produce mucus and digestive juices, as it changes the protein that regulates the movement of salt in and out of cells. Which leads to people thick and sticky mucus and digestive juices, such as pancreatic juices. Whereas people who do not have CF have thin and slippery mucus and digestive juices. The severity of the disease differs from one person to the next, yet the

Cystic fibrosis (CF) is one of the most common fatal genetic diseases in Canada. This disease is the result of a mutation of the cystic fibrosis transmembrane conductance regulator (CFTR), located on chromosome seven. CF causes the body to produce thick and sticky mucus that clogs the lungs, causes infections, and blocks the release of enzymes from the pancreas. The first such defective gene was identified by research geneticist Dr. Lap-chee Tusi in 1989 with his team at the Hospital for Sick Children in Toronto. The mutated copy of the gene is recessive, so a child must inherit both copies of the defective allele from his or her parents in order to express CF. In the past, parents realized that they were carriers only when their child was

Para 4. Cystic fibrosis has a very large toll on the patients’ everyday life. From regular hospital visits to getting a sudden blockage. Most of the time they cannot take part in regular everyday activities because of many struggles, such as a persistent cough, difficulty breathing, tiredness frequent visits to the toilet and frequent muscle cramps. Due to these symptoms majority of CF patients struggle to maintain a normal lifestyle like their peers who are not diagnosed. The parts of the body affected are the the lungs, the digestive system (pancreas & liver) and the reproductive system. In respiratory system the thick mucus clogs the tight air passages and also traps a lot of bacteria. Repeated infections can lead to severe and irreversible