Hypothyroidism is a complex thyroid disorder characterized by the production of thyroid hormones below normal levels, which commonly leads to the development of a broad spectrum of clinical signs and symptoms [1]. Thyroid hormones play an important role in the development and growth of organs and tissues and are essential to maintain quality of life. In addition, these hormones guarantee metabolic demands that interfere with the adjustment of flows and with the quality of digestive secretions, including those of the salivary glands [2].
Alterations in salivary gland morphology have been the subjects of many studies [4-9], which have shown that hypofunction of the salivary gland follows structural atrophy. On the other hand, the effect of hypothyroidism on the salivary glands has been little reported [1,10,11], with emphasis on salivary gland atrophy [2].
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According to Emmelin, Garrett & Ohlin (1974), myoepithelial cells accelerate salivary flow, reduce the luminal volume and contribute to the secretory pressure. Since they are well differentiated, it was believed in the past that myoepithelial cells have a low proliferative capacity [12]. However, today it is known that myoepithelial cells can proliferate and are involved in tumorigenesis [13,14]. Furthermore, studies investigating myoepithelial cells of the salivary glands have demonstrated the proliferative capacity of these cells even under adverse conditions
Hashimoto’s Thyroiditis, also called Hashimoto’s disease is an autoimmune disease in which the body’s immune system attacks the thyroid gland. It was named for the Japanese surgeon who discovered it in 1912 The thyroid is a small butterfly shaped gland in the front of the neck. The thyroid makes hormones called T3 and T4. These hormones regulate metabolism. The thyroid is controlled by hormones of the pituitary gland, which is also called the “master gland.” It is a pea-sized gland located in the base of the brain which, among others, makes thyroid stimulating hormone, or TSH. TSH stimulates the thyroid to make thyroid hormone. With Hashimoto’s disease, the thyroid cells are damaged resulting in the inability to make enough thyroid
Hashimoto thyroiditis is a common disease caused by hypothyroidism. The immune system cells attack the thyroid gland, causing inflammation and eventually destruction of the gland. This reduces the thyroids ability to make hormones. These hormones are known as thyroxine (T4) and tri-iodothyronine (T3) (Better health channel 2015).
Hypothyroidism is a lack of activity in the Thyroid (the Endocrine gland), which is located in the neck. Because it is a part of the Endocrine gland, it plays a major role in the hormonal system; which may cause complications with the pituitary (located in the brain), the ovaries or the testes.
Exophthalmic goiter, more popularly known as Graves’ disease, is an autoimmune disease where too much activity of the thyroid gland leads to the overproduction of thyroid hormones such as T3 and T4. More specifically, an autoimmune disorder is described as “the body's immune system mistakenly identifying healthy cells as foreign invaders and attacking them” (Lam, 2015). This disease affects the thyroid gland, an organ located at the base of the neck just below the Adam's apple. The thyroid gland is a crucial component of the endocrine system, which is responsible for the regulation of a person's metabolism by releasing hormones into the bloodstream. Since the disease affects the thyroid gland, hyperthyroidism is one of the most common results
Hypothyroidism is a disease where the thyroid does not make the accurate amount of hormones. If a person has Hypothyroidism they might encounter constipated, fatigue, weight gain, thinning hair, skin dryness, and or hoarseness of the voice. Peripheral neuropathy might occur after a constant untreated Hypothyroidism. The relationship is not really clear. Hypothyroidism can cause edema. MacKay-sims and Beard think Peripheral neuropathy may be a cause of olfactory disorders. Thyroxine is necessary for normal development of the Nervous System including the make of new olfactory receptor neuron. Hypothyroidism ruins the growth of the olfactory epithelium. Olfactory disorders are commonly caused by upper respiratory tract infections. It is unclear rather subjectively smell and taste is from primary hypothyroidism because a person has to special equipment. So, they decided to focus objectively focus on the relationship between the influence of hypothyroidism and
Hyperthyroidism and hypothyroidism are both disorders of the thyroid gland and both have to do with the secretion of triiodothyronine and thyroxine. The thyroid hormones are stimulated by the thyroid stimulating hormone, which come from the adenohypophysis, and controls the release of triiodothyronine and thyroxine. Hyperthyroidism, also known as Grave’s disease, means that there is means there is too much thyroid hormone in the system. Symptoms are weight loss, high basal metabolic rate, sweating, nervousness, and rapid heart rate. Hypothyroidism, also known as myxedema, is when there is not enough secretion of thyroid hormones. The symptoms are the exact opposite there is weight gain, lethargy, mental sluggishness, and reduced heart rate.
Hypothyroidism is the result of the thyroid gland not secreting adequate amounts of thyroid hormones. With this condition, all metabolic processes slow down. Hypothyroidism originates from various causes. It can be autoimmune in nature when the immune system produces antibodies that attack the body’s own tissues. A pituitary disorder in which the pituitary fails to produce enough TSH has also been reported to be the cause of hypothyroidism. There are other causes noted to result in hypothyroidism such as iodine deficiency, pregnancy, and a thyroidectomy which is the removal of the thyroid glands. During my clinical rotation in the orthopedic unit, I cared for a patient who has a diagnosis of hypothyroidism and has had a thyroidectomy in the past.
Digestion: Low thyroid diminishes the release of Gastrin, which determines the productivity of hydrochloric acid in the stomach, leading to poor protein digestion, sour belly and GERD.
The thyroid regulates your metabolism, your appetite, muscle function, blood pressure, heart rate, among other things. And a way that it interacts with the pituitary is a good example of a negative feedback loop, a method of communication that's common all over the body and especially in the endocrine system. Basically, the pituitary is like the thyroid's thermostat. It can read how much thyroid hormone is in your blood stream and when its levels are low, it spits out a tiny bit of thyroid stimulating hormone, or TSH, which travels to the thyroid. The thyroid, in turn, secretes thyroid hormone, which boosts our metabolism, and that increase in metabolism tells the pituitary to stop sending out TSH. So the effect of the pituitary secretion is
Hyperthyroidism is a disorder which is characterized by a surplus of thyroid hormones. This disease can be caused due to a benign tumour in the thyroid gland (thyroid adenoma), toxic nodular goitre, and over-activity of the thyroid gland. The disease causes unexplained weakness and increases appetite; while other indications are weight loss or gain, hair loss and anxiety, etc. A complete list of the symptoms can be found here.
“The thyroid gland is located proximal to the throat, in front of the neck, under the thyroid cartilage”. The thyroid cartilage is also referred to as the “Adam’s Apple” (“Thyroid Cancer” 1). This “gland produces several important hormones”. These thyroid hormones control body temperature, weight, and energy level. Included in these hormones is “Calcitonin, which helps the body use calcium” (“Thyroid Cancer” 1).
The thyroid gland is prone to more than a few very distinct problems, some of which are very common. "These problems can be broken down into those concerning the production of hormone (too much, or too little), those due to increased growth of the thyroid, causing compression of important neck structures or simply appearing as a mass in the neck, the formation of nodules or lumps within the thyroid which are worrisome for the presence of thyroid cancer, and those which are cancerous" (Norman, 2012).
Hyperthyroidism is a disorder also referred to as an overactive thyroid. This is a condition where the thyroid develops a growth and produces excess amounts of triiodothyronine and other thyroid hormones. The disorder occurs when the elevated serum amounts of T3 and T4 enters the glands. This is one of the most common forms of hyperthyroidism. The major causes of hyperthyroidism are an excess secretion of thyroid hormones together with increased functioning of metabolism in the peripheries of the glands. Historically, hyperthyroidism has not been known for a good amount of time. The symptoms that result in the disorder are often hard to depict. It was until the disorder was discovered among patients that the problem was studied and analyzed for treatment and prevention (Preedy et al 2009).
The thyroid gland is a butterfly shaped endocrine gland that is normally located in the lower front of the neck behind the adam 's apple and along the windpipe. The thyroid gland is very rich with blood vessels. The main purpose of the thyroid is to make, store, and release thyroid hormones into the blood which is then carried to every tissue in the body. How the works is that when you acquired iodine from the food you eat. Some food has a good source of iodine in it, for example iodine is in most foods like milk, salt, bread, etc. The Thyroid gland then takes the right amount of iodine out of your blood and uses it to make two different types of thyroid hormones. The thyroid hormones produced can be either of two different types, either thyroxine or triiodothyronine. According to the article You and Your Hormones, thyroxine is the inactive form of the thyroid hormone while Triiodothyronine is the active form of thyroid the hormone. Thyroid hormones help the body use energy, stay warm and keep the essential body organs working, for example the heart, brain, muscles and other organs. But the thyroid gland influences most of all the metabolic process in the body.
The thyroid is a butterfly-shaped gland positioned on the front of the neck. Its job is to produce thyroid hormones that the body needs for the endocrine, metabolic, and other systems of the body. Sometimes, it can be affected by cancer, infections, or disease. This will cause it to not function at its best, which means it will either produce too much or too little thyroid hormones. When it is too little, this is called “hypothyroidism.”