The Medicines Company Case

As the brand manager for Allround cold medicine, there were many decisions regarding product formulation, strategy, line extensions and product launches over the company’s last 10 periods. The brand was focused on remaining a profitable, mature product family within the cold medicine category, but also maintaining a premium brand image.

Angiomax is considered as a potential substitute for heparin. It has 3 major advantages when compared with Heparin. First, the effects of Angiomax are more accurate and more predictable. Second, it works better among patients at risk for bleeding, where heparin often proves problematic. Third, the product works faster than heparin and patients do not need to wait for 2 – 3 hours to identify the results. The major disadvantage of Angiomax is its high production cost against Heparin. As Heparin has a very long history dated back in 1916, the price is only $2 per unit while the production cost of Angiomax takes nearly $40 per unit.

Defendants, Mark and William Schenkly, have not satisfied the elements required to invoke the shopkeeper’s privilege defense. Conduct by the suspect which lead a shopkeeper to believe that the suspect is attempting to steal is enough to establish reasonable cause. In assessing reasonable cause to detain, Arizona courts consider whether appearances are sufficient to justify a shopkeeper’s belief is reasonable. Kon v. Skaggs Drug Center, Inc., 563 P.2d 920, 922 (1977); Gau v. Smitty’s Super Valu, Inc., 901 P.2d 455, 459 (1995). Defendant Mark Schenkly did not see Mr. Flynn take beer from the cooler, nor did he observe that the beer was missing from the cooler. The statute setting forth the requirements for asserting the shopkeeper’s privilege provides that detainment may only take place for the sole purposes of questioning or

Drug courts have historically been the preferred way to treat drug users/offenders. What are the requirements for an offender who participates in drug court? How does this differ from the LEAD program?

The funding is to be used solely for the development of X and may not be used for any other purposes

f I had to choose only one comprehensive treatment option to fund in New Jersey, I would choose drug courts. Drug courts would be a viable choice because it's already been proven as a valid post-trial method. I would leave drug courts in the post-trial timeline because it naturally seems to make the most sense for rehabilitation. Drug court allows offenders who are non-violent to avoid jail time to receive the specific individual treatment needed. This aspect is why I think drug court is such an important choice, for it treats the offender through a custom like plan designed with their needs in mind. Drug court is an intensive program that has the ability to positively overhaul a persons life. Yet it maintains that the offender being treated,

1. Do pharmaceutical companies have a responsibility to distribute drugs for free or at low cost in developing countries? What are the main arguments for and against such an approach? What are the advantages and disadvantages of giving drugs for free versus offering them at low no-profit prices?

The California Court of Appeals’ decision in Coleman v. Medtronic has made it easier for plaintiffs to pursue medical products liability claims. In the landmark 2014 decision, the court held that the state law tort claims asserted by the plaintiff were not federally preempted. The decision is part of a growing body of medical products liability law regarding the circumstances under which a state law claim can impose "parallel" requirements to those under the Food, Drug & Cosmetics Act (FDCA) and, therefore, avoid federal preemption.

Considering cephalin is most prevalent in the brain, searching and sampling other organs with lower cephalin content might yield these unknown molecules unbound to cephalin and suitable for study. He began studying heart and liver cephalin to test his theory; the liver cephalin was named heparphosphatide, which lead to the name heparin. While studying the deterioration of cephalin in the batches he had prepared, he discovered the exact opposite of what he was expecting, which was anticoagulation activity as opposed to coagulation. Ultimately, this paved the way for further testing on heparin as an anticoagulant and its’ future use the medical sector. Unfortunately, McLean never got to receive the appreciation he deserved for his discovery due to an unfortunate

Pharmaceutical Society of Great Britain v Boots cash chemist (Southern) Ltd was a Court of Appeal decision on the nature of an offer. The court held that a display of an item in a store with a price tag is not enough to constitute an offer. Such a display would be a mere invitation to treat.

Heparin, also known as a blood thinner is given to people to help reduce and stop blood clots that have yet begun to form. It is one of the most common medications given to help thin blood by entering the thrombus and speeding up the activity of one of the body's natural anticoagulant by 2000 times. Heparin may also be given to people who about to undergo surgeries such as: open heart, heart transplant, lung

is another company that has a promising portfolio of drugs for obesity treatment. They recently merged with Mariel Therapeutics so as to enlarge their drug portfolio. The company was formerly known as Adipothermics Inc. and then changed its name in 2011. They were founded by Third Rock Ventures with $34 million investment, but had to shutdown in December 2014.

The drug belongs to a class of low molecular weight heparin (LMWH). Enoxaparin inhibits factor Xa which catalyzes conversion prothrombin to thrombin. As a result, thrombin level decreases and fibrin clot is not formed. It thwarts the progression of a fibrin

Pharmed First Inc. is a widely successful chain pharmaceutical company with 85 drugstores located in Canada’s Atlantic provinces. George Brenner is one of the 6 regional managers and Angela MacFee is a store manager in a mall located in Dartmouth. One of MacFee’s loyal customers have purchased 9 packages of Diet Magic on September 2011 however wanted to return them on May 2012. Subsequently, MacFee reacted hastily and defensively, arguing with Johnston in spite of Pharmed First Inc. return policy (Figure 1). As a result, Johnston wrote a letter to Frank Chen, the president of Pharmed First Inc. and told Brenner to deal with it. He proposed that the company gives Johnston a $500 voucher and that MacFee apologizes. However, MacFee remained inflexible as she also challenged Brenner’s authority.

Heparin is usually identified for its anticoagulant properties, so industrially developed heparin counting the unfractionated heparin (UFH) and low molecular weight heparin (LMWH) are recently being employed in medication and prevention of thrombotic events like deep vein