The Role Of Irritable Bowel Disease ( Ibd )

The relationship between the human gut microbiome to health and disease is strong. Human physiology, metabolism, nutrition, and immune function are all affected by the composition of the gut. If the composition of the gut microbiome is altered in a way that any of these functions are negatively affected, this can lead to disease. The developments of the microbiome, its complexity, and its functionality in health and disease have been extensively studied. In addition, the way in which it is altered has many implications in the cause of diseases, such as bowel disease, obesity, diabetes and cancer.

Crohn’s disease (CD) is a systemic auto-immune disease that is marked by abnormal inflammation of the gastrointestinal (GI) tract, it affects any part of the GI tract from mouth to anus. CD mainly presents in three areas: the small intestine, the colon, and the perianal region. CD mostly occurs between the ages of 15 and 30 years, or between the ages of 60 and 80 years of age. The exact etiology of Crohn’s disease is unknown. As stated by Mazal (2014) “Genetic predisposition—especially familial aggregation—seems to be the strongest independent indicator of which individuals will develop Crohn disease” (p.298). An increase diet in milk protein, milk protein and polysturated fatty acids is also a possible factor in disease incidences. Smoking may also double the risk of developing CD.

The sheer diversity of the microbiota means that bodily disorders associated with the gut region (encompassing the stomach and intestines) are difficult to diagnose, and even harder to find the source of the disorder. Intestinal Bowel Disease (IBD) is a large category of bodily disorders associated with the gut. IBD most commonly manifests itself in two forms – Crohn’s Disease, and Ulcerative Colitis [1]. Crohn’s disease is arguably a more severe form of the disease, as the diseased tissue tends to go deeper into the intestines. Ulcerative Colitis, while still very detrimental and pain causing, causes inflammation of tissue at more of the surface level. The diseases affects a significant portion of the population, with a high rate of new cases discovered - between 20,000 and 100,000 people are diagnosed with types of IBD annually in North America [1]. The role of the microbiota in inducing intestinal diseases has been suspected.

There are major effects in the United States and Europe to help identify the role of microbial communities in the human body. The colon requires a balance of microbial agents that assist with various functions of the body. An imbalance can lead to C.diff., irritable bowel disease (IBD), irritable bowel syndrome (IBS), neurological disorders, and obesity just to list a few. Many of these problems have grown to an epidemic proportion. Both the United States and Europe have started projects aimed at the microbial communities of the body and their roles in our health.

Crohn’s disease is a chronic inflammatory bowel disease that is characterized by inflammation of the digestive, or gastrointestinal tract. It can affect any part of the GI tract, including the mouth and anus. However, Crohn’s most often affects the end of the small intestine (Crohn’s & Colitis, 2016). Crohn’s disease does not have a cure and there is no exact cause for the occurring disease. “Since the exact cause of Crohn’s disease is unknown, it has been linked to a combination of environmental factors, immune function and bacterial factors, as well as a patient’s genetic susceptibility to developing the disease” (History Cooperative, 2014).

Ulcerative colitis is the result of an abnormal response by your body's immune system. Normally, the cells and proteins that make up the immune system protect you from infection. In people with IBD, however, the immune system mistakes food, bacteria, and other materials in the intestine for foreign or invading substances. When this happens, the body sends white blood cells into the lining of the intestines, where they produce chronic inflammation and

This review will explain Crohn’s disease and Ulcerative colitis, two types of inflammatory bowel disease that affect millions of people. These diseases are chronic that affects certain parts of the intestine gastrointestinal tract. People who has this disease are troubled with a variety of side effects that they will have to live with for the rest of their lives. To this day, there are no medical cure for these diseases, however there are several treatment options that are helpful. These diseases are still being studied for researchers to fully understand the causes, possible preventions, and cure for IBDs. Countless researches and studies are still under development, there have been many discoveries thus far, but nothing concrete.

A study of 20 patients with Crohn’s disease, conducted by Jones et al, took part in a controlled trial in which remission was maintained by either an unrefined carbohydrate fibre rich diet or a diet which excluded specific foods to which a patient was intolerant. They found that 7 out of the 10 patients on the exclusion diet remained in remission for 6 months compared with none out of the 10 on an unrefined carbohydrate fibre rich diet [7].

Crohn’s Disease is a chronic inflammation of the gastrointestinal (“GI”) tract that can occur anywhere along the alimentary canal from the mouth to the anus. It is the second most common form of Inflammatory Bowel Disease (“IBD”) after Ulcerative Colitis and can be hard to distinguish from it due to the overlapping signs and symptoms. They are not, however, the same. With Crohn’s Disease the inflammation most often occurs in the small intestine at the end of the ileum and continues into the beginning of the colon, but inflammation may be found in multiple places along the digestive tract at the same time with normal, unaffected areas in between the distended areas. Furthermore, the disease will spread through every

Crohn’s disease (CD) involves the entire alimentary tract and is characterized by focal exacerbations, with intermittent activity throughout the patient’s life. The etiology of Crohn’s disease (CD) remains largely unexplained, but there have been major advances in recent years concerning the pathogenic mechanisms underlying intestinal inflammation. There is a multifactorial character of the disease, in which a genetic predisposition, the external environment, intestinal microbial flora, and the immune system are all involved. Systemic symptoms include unexplained fever, weight loss, and extraintestinal symptoms such as arthralgias and perianal abscess. Delays by the patient in seeking medical help and by the physician to identify the disease

Crohn’s Disease is an inflammatory disease that affects the digestive system. According to an international team of researchers, it is now believed that a fungus in the gut helps develop the disease. Researchers found that those with Crohn’s were more likely to have one type of fungus (Candida Tropicalis) and two types of bacteria in their body. It was found that the fungus and bacteria work together to create a bacteria that sticks to the intestines and cause it to become inflamed.

To conclude, irritable bowel syndrome (IBS), that affects 5-15% of the world inhabitants, is a gastrointestinal indisposition which impacts the bowel function. IBS is universal, but more prevalent in women than men. The definite origin of IBS has not been labeled, but researchers have concluded that it is a blend of bad dieting, hormones,

Inflammatory bowel disease (IBD) can be defined as the chronic condition (it is persistent/ long-standing disease) resulting from inappropriate mucosal immune activation. Inflammatory bowel disease (IBD) can start at any age. However, it is frequently seen among teenagers And also among young adults in their early twenties, both genders can be affected by this disease. There are two conditions that traditionally comprise inflammatory bowel disease (IBD): Ulcerative colitis and crohns disease. Comparison between Ulcerative colitis and crohns disease are clinically useful, because distinguishing between the two conditions allow specialists to choose the right management way. Comparison between Ulcerative colitis and crohns disease are

This study was conducted because Irritable Bowel Syndrome (IBS) is the most common of the functional gastrointestinal disorders (Ljótsson et al., 2010). This problem leaves many people with a debilitating health condition that affects their daily lives, along with their mental health. The goal of this study, conducted by Ljótsson and colleagues, was to use mindfulness and exposure therapy techniques to reduce experiential avoidance because it increases IBS inconveniencies. Mindfulness techniques in this study consisted of having the subject be involved in “in the moment” mental states. Then, exposure techniques are used to have the subject combat the feelings to an aversive stimulus, and to feel the anxiety rather than using avoidance to alleviate

The term Inflammatory Bowel Disease (IBD) is a general name given to a few disorders that all fall under the category of inflamed intestines (they become red and swollen.) This is usually due to a reaction the body causes against its own intestinal tissue. The two most common types of Inflammatory Bowel Disease are Ulcerative Colitis (UC) and Crohn’s Disease (CD). Crohn’s disease can affect any part of the gastrointestinal tract; however, it more commonly affects the small intestine or colon.