Thyroxine Research Paper

Week 3 – LOM Assignment The thyroid is responsible for taking iodine and converting it into thyroid hormones which are released into the blood stream and transported throughout the body where they control metabolism.1 The thyroid is a vital part of the human body as every cell in the body depends on it for metabolic regulation. Too much or too little thyroid hormone secretion can result in hyperthyroidism or hypothyroidism. Hyperthyroidism is caused when the thyroid secretes too many thyroid hormones. Hyperthyroidism causes a rapid heart rate, elevated blood pressure and tremors. Other symptoms include increased nervousness, inability to concentrate, weakness, restlessness, difficulty sleeping, frequent bowel movements, weight loss and irregular

Incidentally, there are actually two compounds made in the thyroid that are called thyroid hormone. The most abundant is T4, also known as thyroxine, which is then converted to T3, or triiodothyronine. T3 is the active form that produces the effects on metabolism.

The health care provider ordered blood work that included thyroid-stimulating hormone, triiodothyronine, thyroxine, and radioactive iodine uptake to confirm the diagnosis of hyperthyroidism. The labs returned with an elevated level of triiodothyronine and thyroxine, while the thyroid-stimulating hormone was decreased. There was also an

The endocrine system is the second greatest control system of the body and has many effects on the tissues and organs. The thyroid gland, which is a part of the endocrine system, releases a hormone that maintains metabolism. This hormone is thyroxine. Thyroxine production is controlled by thyroid stimulating hormone, which is released by the pituitary gland. TSH stimulates the thyroid gland to produce thyroxine. In this experiment, the effects of TSH and thyoxine on metabolic rate are investigated.

The thyroid gland is the gland that makes and stores hormones that help regulate the heart rate, blood pressure, body temperature, and metabolism. Thyroid hormones are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions in the body. Thyroid hormones also help children grow and develop. The thyroid gland is located in the lower part of the neck, below the Adam's apple, wrapped around the trachea. It has the shape of a butterfly with two lobes attached to one another by a middle part called the isthmus. The thyroid uses iodine, a mineral found in some foods and in iodized salt, to make its hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine

Taking L-thyroxine is the main treatment mechanism; therefore, medication compliance is the one of the most important part in education. The clinical effect of L-thyroxine may include normalizing abnormalities associated with hypothyroidism. Optimal treatment of hypothyroidism may lead to improvement of various symptoms. In neuropsychological aspect, patients may show improved motor skills, myopathy and depression. With treatment, patient’s overall energy level may enhance constipation symptoms may improve and weight problem may lessen if thyroid balance was a main contributor. It has been shown that treatment of hypothyroidism would also improve lipid profiles in patients (Roe, 2015).

The thyroid stimulating hormone receptors are G-protein linked and are found extracellularly in the thyroid glands. When activated, synthesis of hormonally active iodothyronines T3 (triiodothyronine) and T4 (thyroxine) begins (Park and Chatterjee, 2005). This process begins with iodide is transported into the thyroid gland by the sodium iodide symporter found in the membrane of thyroid follicular cells (Park and Chatterjee, 2005). The iodotyrosine residues monoiodotyrosine and diiodotyrosine are then formed through iodine organification where the iodide is oxidised using hydrogen peroxide and then bound to tyrosine in the thyroglobulin (Park and Chatterjee, 2005). The residues then bind together to form the hormonally active iodothyronines aforementioned (Park and Chatterjee, 2005). Many catalytic enzymes mediate this process and are needed to ensure proper thyroid hormone synthesis. Failure in any steps of the synthesis process leads dyshormonogenesis and could be the result of genetic defects. Adequate synthesis of active thyroid hormone is necessary for the regulation of many developmental processes (Richter, C. et al.,

The thyroid gland is found in the front of the neck and produces two main hormones. The hormones are called thuroxine (T4) and Triiodothyronine (T3). Together these hormones regulate the body’s metabolism by increasing energy use in cells, regulate growth and development, help to maintain body temperature and aid in oxygen consumption. These two hormones are regulated by hormones produced by the hypothalamus and pituitary gland. The hypothalamus senses changes in body’s metabolic rate and releases a hormone known as thyropin-releasing hormone (TRH). This hormone then flows through connecting vessels to the pituitary gland which signals it to release another hormone. This hormone is known as thyroid-stimulating hormone (TSH). TSH then makes

In a normally functioning body, Thyroxine (T4) and Triiodothyronine (T3) are hormones produced by the thyroid gland. They help control the rate at which the body uses energy and are regulated by a feedback system. Thyrotropin or Thyroid-Stimulating Hormone (TSH) from the pituitary gland stimulates the production and release of T4 (primarily) and T3 by the thyroid. Most of the T4 and T3 circulates, bound to protein, in the blood. A small percentage is free (not bound).

The thyroid may be very small and seem insignificant in the grand scheme of things, but it plays a very important role in the function of the body. The thyroid gland takes iodine (which is found in many foods) and it converts it into thyroid hormones. These hormones are thyroxine (t4) and triiodothyronine (T3). Thyroid cells are the only cells in the body which can absorb iodine. Hyperthyroidism and hypothyroidism are two conditions that stem from the thyroid malfunctioning. This paper will go into the about the two conditions, the similarities, and the differences.

The aim of the hypothyroid treatment is to reverse clinical progression and correct metabolic derangements which can easily attained in the majority of the patients by the daily oral administration of the synthetic thyroxine (T4). The thyroid

Within the endocrine system, the thyroid gland plays an important role on daily function and activity. The thyroid gland is a butterfly-shaped gland located in front of the neck, right below the larynx. The thyroid gland produces thyroid hormones, primarily T3 (thyroxine) and T4 (triiodothyronine) (NIDDK, 2013). It is very important that the body produces the appropriate amount of thyroid hormones because these hormones affect nearly every organ in the body. More specifically, thyroid hormones regulate an individual’s metabolism such as heart rate, energy use, energy level, and protein synthesis (Family Doctor, 2014).

The thyroid, found in the throat, is a gland which produces hormones that keep your body’s engine going optimally. Too much or too little thyroid produced hormones affect every aspect of daily life. If your thyroid is out of sync with your other organs symptoms and the extenuating consequences change everything. Your gut health is important to digestion, absorption of nutrients, and require thyroid hormones to sustain a healthy body. How the thyroid controls digestion is important in understanding what to do about the problems affecting the gut.

The levels of hormones in the body can be regulated by several factors. The nervous system can control hormone levels through the action of the hypothalamus and its releasing and inhibiting hormones. For example, TRH produced by the hypothalamus stimulates the anterior pituitary to produce TSH. Tropic hormones provide another level of control for the release of hormones. For example, TSH is a tropic hormone that stimulates the thyroid gland to produce T3 and T4. Nutrition can also control the levels of hormones in the body.The thyroid hormones T3 and T4 require 3 or 4 iodine atoms, respectively, to be produced. The people lacking iodine in their diet will fail to produce sufficient levels of thyroid hormones to maintain

The study by Framingham assessed a random population of the ageing persons and got a 4.4% thyroid deficiency incidence. The verification of this study was shown by a clearly eminent serum thyrotropin level more than ten µIU/mL. Females displayed thyroid deficiency (5.9%) more frequently than males (2.3%). The serum thyroxine (T4) level wasn’t a subtle degree of thyroid insufficiency. Among those with apparently preeminent serum TSH levels, only 39%