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What Is The Therapeutic Index

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Hi Professor and Classmates,
Therapeutic index refers to the relationship of toxic and therapeutic dosage. According to Smith “therapeutic index of a drug is the ratio of the dose that produces toxicity to the dose that produces a clinically desired or effective response.” Therefore, the dose of the drug is a cause of the toxic and therapeutically. Drugs that are safe to use have a higher index and the dangerous drug has a lower therapeutic index. I think that the most dangerous is the with the higher index because people can overdose or they get addicted to the drug and that’s when they start using illicit drugs. The addiction to barbiturates can be serious because it is measured by the therapeutic index. An example on how phenomenon

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