ZIKV Response Paper

Decent Essays
Great concerns have been made by the public on the outbreak of Zika virus (ZIKV), a mosquito-borne flavivirus, on the influences it may bring to human fetal. Numerous research have been made analysing the impact on human fetal if their mothers are being infected by ZIKA virus during pregnancy and there are still more to be revealed. Freitas et al. (2016) reports the ocular findings in infant with microcephaly (birth defect with abnormal smallness of head) while Mlakar et al. (2016) reveals the consequences of ZIKA with microcephaly.

Driggers et al. (2016)
Calvet et al.(2016)

This annotated bibliography will discuss how the Zika virus contributes to the increased risk of congenital microcephaly.

This article examines the ocular abnormalities of infants in connection with microcephaly, that may be caused by speculated inborn ZIKA virus infections. The research was done by involving twenty-nine infants that suffered from microcephaly, suspected to be due to inborn ZIKA infections. Together with their mothers, they underwent ophthalmologic evaluations using a wide-field digital imaging system. ZIKA infection symptoms were presented during pregnancy of 23 out of 29 mothers. Furthermore, 17 eyes of 10 children, out of 29 infants (58
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The research aimed at detecting and sequencing ZIKA virus from amniotic fluid of fetuses with microcephaly in Brazil. It is done by involving two pregnant women whose fetuses were detected with microcephaly. Serum, urine, and amniotic fluid samples of the two women were collected for series of examinations and tests. Zika symptoms including fever and rash were observed from the two women at 18 week and 10 week of pregnancy. Zika virus genome has been detected in both women’s amniotic fluid but not in any of their urine or serum. ZIKA virus is shown to be able to cross the placental barrier and cause impacts on human
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