muscular dystrophy has many forms and therefore symptoms can vary between the variations. Overall symptoms include the weakening of skeletal muscles and the defect and death muscle tissues. Duchenne muscular dystrophy is the most common and affects young boys such as Eddie.
Eddie is an 11 year old boy and has been diagnosed with Duchenne muscular dystrophy. The symptoms appeared at the age of 5 and had led to the weakening of his leg and arm muscles and the eventual need of a wheelchair. Some of these symptoms include:
• Frequent falls
• Awkward manner of walking
• Fatigue and low endurance
• Loss of motor skills (jumping, running)
• Eventual loss of ability to walk
While Eddie is able to move around
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Additionally, contractures, which hinder the movement of joints, may occur along with the inability to bend the elbows. Heart problems will also occur and by the age of 20, they will become more common. If left untreated, the patients affected will eventually suffer a stroke and die. Emery-Dreifuss patients will also experience abnormal heartbeats that can lead to even slower one. However, the insertion of pacemaker can easily aid to these problems and be lifesaving. Limb-girdle muscular dystrophy is a type of muscular dystrophy where the muscles affected are the hips and shoulders, which are also known as the limb girdle muscles. Some symptoms of Limb-girdle are muscle weakness/atrophy, myoglobinuria, myotonia, elevated serum CK, and in a fifth of the cases, cardiomyopathy. The symptoms continue to get worse over time and sometimes they can get worse very quickly. The symptoms tend to appear around the age of 10 or 12, and the person may lose mobility within 20-30 years. Limb-girdle is not a fatal disease, and death usually is caused by a secondary disease. But in the most severe cases the lifespan is shortened to about 20-30 years. Facioscapulohumeral muscular dystrophy affects the face, scapula and upper arms. Symptoms develop early in childhood and will progress throughout the years and by the age of 20, almost all people who are affected will show symptoms of Faciosapulohumeral
Muscular dystrophy is a degenerating disease, in which the skeletal muscles degenerate, lose their strength, and cause increasing disability and deformity. Muscles attached to the bones through tendons are responsible for movement in the human body, however, in muscular dystrophy the muscles become progressively weak. As the muscle fibers
According to the " Muscle Diseases" by Patrick F.Chinnery in the Goldman's Cecil Medicine, 24th Ed 2012, "Duchenne Muscular Dystrophy affects about 1 in 3500 males. About one third of the cases arises from a de novo mutation without a family history."
Listener Relevance: Duchenne Muscular Dystrophy (DMD), is more common than people think and chances are sooner or later you will know of or see somebody affected by this disease.
Duchenne muscular Dystrophy (DMD) is the most common out of nine types of muscular dystrophy. This genetic disorder causes progressive muscular weakness, and deterioration due to the lack of a protein called Dystrophin. This protein keeps the muscles in tack, so when it's missing, the muscles slowly break down. (MDA, 2015)
According to Green (2014) the (DMD) gene for dystrophin, which is a protein that is present in muscles, is the second largest gene. A deficiency of dystrophin results in the damage of muscle fibres, resulting in a loss of muscle functioning. This disorder affects mainly the legs and pelvic region of the body. However it could also affect the heart, the respiratory system, as well as rarely the brain. Duchenne
Ben has Duchenne Muscular Dystrophy (DMD). DMD is a degenerative disease of the muscles. When someone has this disease their muscles do not produce enough dystrophin to stay together. This causes the muscles to deteriorate over time. With proper care, the rate of muscle degradation can be slowed down. Duchenne muscular dystrophy is a genetic disorder characterized by progressive muscle degeneration and weakness. Muscle weakness can start as early as age three. It first affects the hips, pelvic area, thighs, and shoulders. This disease is still fatal and will be until further studies and research are done to find ways to cure this disease.
This rare disease affects 1 in 3,500- 6,000 males. A key indicator a child has Duchenne is muscle weakness. This means a child may have difficulty getting up after sitting down and difficulty walking. Often times kids with Duchenne are walk on there toes and can
Limb-girdle muscular dystrophy is a form of the disease that affects both boys and girls equally and appears in the teenage years all the way into adulthood. It usually progresses slowly over time and within 20 years walking will become difficult or impossible, eventually a wheelchair
Overall, the lack of dystrophin in DMD individuals causes many problems in different aspects of metabolism. It has a massive effect on muscles, affecting the shoulders, hips, calves, thighs, pelvic area first. Like other muscular dystrophies, DMD affects the voluntary muscles first and then will progress into other muscles. Limb-girdle muscular dystrophy is another type out of the many that affect voluntary muscles. Specifically, it targets the hips and shoulders.
Duchenne Muscular Dystrophy (also referred to as DMD) is a type of muscular dystrophy that weakens the muscles that we need to support our body, body weight, to stand, and to move around. It also can cause you to have scoliosis. Some of the main causes for DMD are genetic disorders, mutations, and DMD has to be passed down throughout everyone in that family for generations. The symptoms you can have if you have DMD are weak muscles, lack of strength, and difficulty walking. DMD is a negative mutation because it affects your muscles horribly bad that you can get a disability of walking and even moving. You need to tell your doctor immediately if you experience any symptoms. If you don't tell your doctor, you may find yourself in a very difficult situation where you can't get up or can't get something you need. When you do talk to your doctor, you will have an advantage of getting the help you need.
Even though the annual telethon is over, muscular dystrophy—all nine forms—still exists. MD presents with a combination of muscle weakness and muscle wasting.
Muscular dystrophy (MD) is a genetic disorder caused by incorrect or missing genetic information that leads to the gradual weakening of the muscle cells. Various causes lead to weak and deteriorating muscles depending on the type of muscular dystrophy the patient was affected by. However, there are many causes for muscular dystrophy due to the fact that there are thirty forms of muscular dystrophy, which are categorized under several categories. All are ultimately caused by autosomal recessive, autosomal dominant, sex-linked, and random mutations in very rare cases.
Muscular dystrophy is a rare disease. 349 out of 2.37 million males aged between five and twenty-four had Duchenne or Becker muscular dystrophy in 2007. Males are more likely to be affected. It is very rare for females to have the disease.
In most cases it is an X-linked genetic disorder that is carried by the mother but only manifesting in sons. It is caused by a mutated gene and results in low levels of dystrophin. Whereas normal muscles have dystrophin to help keep their shape and strength, those who suffer from MD tend to lack proper levels of this protein or will not be able to produce it at all. According to the Muscular Dystrophy Association, there are nine types of DM, with the two most common types being Duchenne and Becker. The symptoms of each type tend to differ, but Duchenne and Becker have similar signs: muscle weakness in the extremities, difficulty walking, lordotic posture, and enlarged calf muscles. The most easily recognizable sign of MD is a “toe gait,” which is characterized by the patient walking on his/her toes and walking with an abnormal forward curvature of the spine in the lumbar region. This gait is the result of the lower leg muscles compensating for upper leg muscles that no longer function, and the lordotic posture is due to a tilted pelvis caused by weakened muscles around the
Muscular dystrophy is a disease with different versions that effect most body systems. The main systems are the heart, eyes, spine, brain, nervous respiratory, musculoskeletal and endocrine system. The main purpose of all nine major types of muscular dystrophy is ongoing condition that makes your muscles weak resulting in loss of mass/functions. A person with muscular dystrophy lifestyle would be affected depending upon what type they have. It will have a huge effect on activated due to muscle weakness but for the most part they should be