Skip to main content
What Is the Difference between Alpha and Beta Glycosidic Bonds?

Answer – The main difference between alpha and beta glycosidic bonds lies in the orientation of the anomeric carbon atoms involved in bond formation.

Explanation: 

Alpha and beta glycosidic bonds are covalent bonds formed between carbohydrate molecules and other molecules. An alpha-glycosidic bond occurs when both carbons involved have the same stereochemistry, while a beta-glycosidic bond forms when the two carbons have different stereochemistry. These bonds are commonly found in disaccharides, such as sucrose, lactose, and maltose, where they link monosaccharide units together in either the alpha or beta orientation. 


In an alpha glycosidic bond, the hydroxyl group attached to the anomeric carbon is below the plane of the sugar ring, while in a beta glycosidic bond, this hydroxyl group is above the plane of the sugar ring. This distinction in orientation affects the overall structure and properties of the glycosidic bond, influencing how carbohydrates interact and function in biological processes.

Structure of sucrose
Glycosidic linkages are covalent bonds between carbohydrates and other molecules.

SHOW MORE TEXTBOOK SOLUTIONS+