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- 2.) How can these pathological factors listed below affect drug effects? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfunction1) A patient with heart failure, hypertension and hyperlipidemia is taking furosemide, captopril, atenolol, and simvastatin. During a scheduled physical examination, about a month after starting all the drugs, the patient reports a severe, hacking and relentless cough. Which of the following is the most likely cause of the cough? An expected effect of the captopril An allergic reaction to the statin Dyspnea due to captopril’s bronchoconstrictor action Hyperkalemia caused by an interaction between furosemide and captopril Excessive doses of furosemide, which lead to hypovolemia 2) Flecainide and propafenone are in Vaughan-Williams (antiarrhythmic) Class IC. What is the clinically relevant “take home” message about this class of drugs? Are only given for arrhythmias during acute myocardial infarction (MI) Are particularly suited for patients with low ejection fraction or cardiac output Are preferred drugs for relatively non-severe ventricular arrhythmias Have a significant…1.) How can these physiological factors listed below affect drug effects? Explain each. - diurnal rhythm - acid-base balance - hydration - electrolyte balance
- 5. What conditions should not be used with Cetirizine?1.) How can these physiological factors listed below affect drug effect? Explain each. - diurnal rhythm - acid - base balance - hydration - electrolyte balance 2.)1.) How can these pathological factors listed below affect drug effect? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfuntion1. What is the medication LIDOCAINE's mode of action?
- 9 Give four therapeutic functions that aspirin (acetyl salicylic acid) has. Explain each in details.1.) How can these physiological factors listed below affect drug effects? Explain each. - diurnal rhythm - acid-base balance - hydration - electrolyte balance 2.)1.) How can these pathological factors listed below affect drug effects? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfunction3. why is amiodarone (Cordarone) use for dysrrhythmia?
- 4. What pathologies are treated with hydrochlorothiazide?ACE-I are known renoprotective (protect the kidney) Is BB (beta blocker) is renoprotective,, yes or NO and Why?? Is CCB (calcium channel blocker) is renoprotective?, yes or no and Why?? Pathophysiology and pharmacologest1. Explain the difference between Toxicokinetics and Pharmacokinetics. 2. How is Absorption, Distribution, Metabolism, and Elimination an inter-related process.