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- Construct a map for the genes d,e,f. Assume that: d and e = 3%; e and f = 5%. Give 2arrangements of the genes/maps.2. You are making a genetic map and use a cross to measure the distance between genes H and J as 40cMand the distance between J and M as 20cM. When you measure the distance between genes H and M, you get 50 cM. Do the following (A-C). (A) Draw and label a map of genes H, J, and M. (B) What is the genetic distance between genes H and M? How do you know? (Answer in 1 sentence) (C) Complete the table (right). For each pair of genes, write “yes” or “no” to indicate whether the pair of genes are“linked genes” and/orpart of the same“linkage group”.4. Marfan syndrome is a genetic trait caused by in a dominant allele. The trait causes a weakening of the aorta that can be fatal. A teenager whose mother has the syndrome (but whose maternal grandfather was not affected), and whose father was unaffected, is concerend that she may have the trait. a. What is the phenotype of each of her parents? Genotype? b. What is the chance that the teenager has Marfan syndrome?
- 1. Discuss the basic structure and function of DNA as the genetic material. 2. Give the function of DNA in the transmission of trait from parent to offspring3. Discuss how Mendel formulated the Law of Inheritance in his pea plant experiment1. There are two different variations at STR locus THO1. Where did these variations come from? b) The STR locus D21S11 only has one variation. Why?6.8 Define a map unit and explain why map units best reflect the real distances between two genes only when the genes are relatively close together.
- 1.Why are punnet squares a useful model for studying traits and genetic disorders? 2.Make a dihybrid cross Punnett square for the dihybrid cross YyRr and yyrr.1. Given the karyotype shown here, is this a male or a female? What would the genotype/phenotype of this individual be?1. Why is the relationship P=p2 used for homozygous loci?
- 1) By convention, the recessive trait will determine the abbreviation used to track crosses if it is a mutant condition, since it stands out in contrast to the rest of the population. For example, if pea pods are typically green in color, a mutant condition might result in yellow pea pods; therefore, the lowercase letter ‘y’ would be used to depict the mutant state, yellow, while uppercase ‘Y’ would depict the wildtype (wt) condition, green. Remember that the mutant condition is not necessarily always recessive. 1 A) . If green is dominant wt (Y) and yellow is a recessive mutant condition (y), depict a Yy father mated with a YY mother in the Punnett. 1B) Considering the dominant allele, what colors are the parents in the cross above? Yy = _____________________ YY = _____________________ 1C) What colors are the offspring in the cross above? 1D) What is the phenotypic ratio of the offspring? 1E) What is the genotypic ratio of the offspring? (Remember, the genotypic ratio is based…1) Perception of a bitter taste from phenylthiocarbamide (PTC) is dominant (T) to not being able to taste PTC. Albinism is recessive to normal pigmentation (A). The genes controlling these traits are on separate chromosomes. a. A normally pigmented woman who cannot taste PTC has a father who is an albino taster, marries a many homozygous for normal pigmentation who is a PTC taster, but whose mother did not taste PTC. What are the genotypes of the woman and man listed here? b. Assuming the man and woman in the above section have children, what percentage of these children will be albino? c. What percentage of these children will have the same phenotype as their mother?1. Make a diagram / illustrate and explain the sample study of Mendel to show the occurrence of the following: a. incomplete dominance b. overdominance c. co-dominance
