1. Create a flowchart for the synthesis and purification of phenacetin. Draw out your steps for the extraction process and label the organic and aqueous layers in your diagrams. Indicate where the product is in each step.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter23: Amines
Section: Chapter Questions
Problem 23.52P
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1. Create a flowchart for the synthesis and purification of
phenacetin. Draw out your steps for the extraction process
and label the organic and aqueous layers in your diagrams.
Indicate where the product is in each step.
2. Draw the mechanism for the deprotonation of the phenol
group of acetaminophen by potassium carbonate. Label the
acid, base, conjugate acid and conjugate base. How do you
know potassium carbonate is a strong enough base to do
this deprotonation?
Transcribed Image Text:1. Create a flowchart for the synthesis and purification of phenacetin. Draw out your steps for the extraction process and label the organic and aqueous layers in your diagrams. Indicate where the product is in each step. 2. Draw the mechanism for the deprotonation of the phenol group of acetaminophen by potassium carbonate. Label the acid, base, conjugate acid and conjugate base. How do you know potassium carbonate is a strong enough base to do this deprotonation?
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