1. During a study of metanephric (definitive) kidney development in an experimental animal, a mutation is induced in the Wilms tumor suppressor gene (WT 1) so that it is no longer expressed in the metanephric mesenchyme. Results show that the mesenchyme fails to respond to inductive signals. This mutation is most likely to direclly affect development ol which of the following? A) Calyces  B) Collecting ducts C) Proximal tubule D) Renal pelvis E) Ureters

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