1. Eli Lilly Corporation produces human insulin from genetically engineered E. coli bacteria. The insulin must be carefully purified through several protein purification steps before it can be injected by diabetics to manage their blood glucose concentration. Through each step in the purification, the concentration of insulin can be monitored very specifically but it is also important to keep track of the total protein concentration. Explain why.
1. Eli Lilly Corporation produces human insulin from genetically engineered E. coli bacteria. The insulin must be carefully purified through several protein purification steps before it can be injected by diabetics to manage their blood glucose concentration. Through each step in the purification, the concentration of insulin can be monitored very specifically but it is also important to keep track of the total protein concentration. Explain why.
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter47: Animal Nutrition
Section: Chapter Questions
Problem 13TYK
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Here it is said that genetically modified E. coli bacteria are used by Eli Lilly Corporation to create human insulin. Before people with diabetes may infuse insulin to control their blood glucose levels, the insulin must be purified. We must determine why monitoring the total protein concentration during this procedure is also necessary.
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