1. Eli Lilly Corporation produces human insulin from genetically engineered E. coli bacteria. The insulin must be carefully purified through several protein purification steps before it can be injected by diabetics to manage their blood glucose concentration. Through each step in the purification, the concentration of insulin can be monitored very specifically but it is also important to keep track of the total protein concentration. Explain why.

Biology: The Dynamic Science (MindTap Course List)
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Chapter47: Animal Nutrition
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1. Eli Lilly Corporation produces human insulin from genetically engineered E. coli bacteria. The
insulin must be carefully purified through several protein purification steps before it can be
injected by diabetics to manage their blood glucose concentration. Through each step in the
purification, the concentration of insulin can be monitored very specifically but it is also
important to keep track of the total protein concentration. Explain why.
Transcribed Image Text:1. Eli Lilly Corporation produces human insulin from genetically engineered E. coli bacteria. The insulin must be carefully purified through several protein purification steps before it can be injected by diabetics to manage their blood glucose concentration. Through each step in the purification, the concentration of insulin can be monitored very specifically but it is also important to keep track of the total protein concentration. Explain why.
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Here it is said that genetically modified E. coli bacteria are used by Eli Lilly Corporation to create human insulin. Before people with diabetes may infuse insulin to control their blood glucose levels, the insulin must be purified. We must determine why monitoring the total protein concentration during this procedure is also necessary.

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